DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-gamma and Igsf9

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001139272.1	Gene:	Igsf9 / 93842	MGIID:	2135283	Length:	1179	Species:	Mus musculus

Alignment Length:	354	Identity:	88/354 - (24%)
Similarity:	134/354 - (37%)	Gaps:	89/354 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 PEFIGFINNVTYPAGREAILACSV----RNLGKNKVGWLRASDQTVLALQ-------------GR 86
            ||.:..:..    ||..|:|.|.:    .:...:.:.|||......:.:|             ||
Mouse    24 PEVVSVVGR----AGESAVLGCDLLPPAGHPPLHVIEWLRFGFLLPIFIQFGLYSPRIDPDYVGR 84

  Fly    87 VVTHNARISVMHQDMHTWKLKISKLRESDRGCYMCQI----NTSPMKKQVG----CIDVQVPPDI 143
            |......           .|:|..||..|:|.|.|::    ..||.:....    .:.|..||.
Mouse    85 VRLQTGA-----------SLQIEGLRVEDQGWYECRVLFLDQHSPEQDFANGSWVHLTVNSPPQ- 137

  Fly   144 INEESSADLAVQEGEDATLTCKATGNPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLRLL 208
            ..|.....|.|:|.|..||.|.|.|:|||.|||:....::       .:...:|:..|| :|.:.
Mouse   138 FQETPPLVLEVKELEAVTLRCVARGSPQPYVTWKFRGQDL-------GKGQGQVQVQNG-TLWIR 194

  Fly   209 RLERRQMGAYLCIASNDVPPAVSKRVSLSVQFAPMVRAPSQLLGTPLGSDVQLECQVEASPSPVS 273
            |:||...|.|.|.||:. ..:::....|.|...|::..|..........||.|.|:.||.|:.::
Mouse   195 RVERGSAGDYTCQASSS-EGSITHATQLLVLGPPVIVVPPSNSTVNSSQDVSLACRAEAYPANLT 258

  Fly   274 Y-WLKGARTSNGFASVSTASLESGSPGPEMLLDGPKYGITERRDGYRGVMLLVVRSFSPSDVGTY 337
            | |.:     :|......:.|:|   ...:|:||.                |.:::..|.|.|.|
Mouse   259 YSWFQ-----DGVNVFHISRLQS---RVRILVDGS----------------LWLQATQPDDAGHY 299

  Fly   338 HCVSTNSLGRAEGTLRLYEIKLH-PGASA 365
            .||.:|..             || |.|||
Mouse   300 TCVPSNGF-------------LHPPSASA 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	23/116 (20%)
		Ig	47..129	CDD:299845	22/102 (22%)
		Ig	140..238	CDD:299845	31/97 (32%)
		IG_like	247..355	CDD:214653	24/108 (22%)
		Ig	256..351	CDD:299845	23/95 (24%)
Igsf9	NP_001139272.1	IG_like	28..110	CDD:214653	20/96 (21%)
		Ig	136..223	CDD:386229	30/96 (31%)
		Ig_3	227..305	CDD:372822	24/101 (24%)
		Ig	341..404	CDD:386229
		Ig	436..500	CDD:319273
		FN3	508..599	CDD:238020
		FN3	625..715	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	767..807
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	819..842
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	942..974
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1016..1079
		PDZ-binding	1177..1179
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900