DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-gamma and zgc:152904

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001070212.1	Gene:	zgc:152904 / 767777	ZFINID:	ZDB-GENE-060929-856	Length:	809	Species:	Danio rerio

Alignment Length:	369	Identity:	88/369 - (23%)
Similarity:	142/369 - (38%)	Gaps:	81/369 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 KCGSGSTQNQHHESSSQLD----------PDPEFIGFINNVTYPAGREAILACSVRNLGKNKVGW 72
            :|.:...:.|..|::..|:          ..|:        .:..|.:|.:.|.|.:.....|.|
Zfish    61 RCQAADAKGQSQEATVVLEIYQKLTFREVKTPQ--------EFRQGDDAEVVCDVISSPVPAVSW 117

  Fly    73 LRASDQTVLALQGRVVTH--NARISVMHQDMHTWKLKISKLRESDRGCYMCQINTSPMKKQVGCI 135
            .         .:.|.:|.  |:|..|    :.|..|:|.|:.::|.|.|.|:......    |.|
Zfish   118 F---------YKNREITSEPNSRFQV----LPTNNLQILKVGKADEGAYRCEARVEAR----GEI 165

  Fly   136 D-------VQVPPDIINEESSADLAVQEGEDATLTCKATGNPQPRVTWRREDGEMILIRKPGSRE 193
            |       |.|||.:...:.|.:......|..|.||..:|:|.|:|||..: |..|     ...|
Zfish   166 DFRDIVVQVNVPPVLSVPQQSFNATADYQESVTFTCVTSGSPDPQVTWYWK-GHAI-----EHSE 224

  Fly   194 LMKVESYNG--SSLRLLRLERRQMGAYLCIASNDVPPAVSKRVSLSVQFAPMVRAPSQLLGTPL- 255
            ...:.:.||  |:|.:..:::...|.|:|.|||....:.| ::.|.|...|.:   :||.....
Zfish   225 QYVLNTMNGGKSTLTVKNIKQTDGGPYMCRASNKAGSSES-QLFLKVFVQPHI---TQLRNVTAV 285

  Fly   256 -GSDVQLECQVEASPSPVSYWLKGARTSNGFASVSTASLESGSPGPEMLLDGPKY--GITERRDG 317
             ||...:.|..|..|.|...|   .|.|:|.:                ..||.|.  |..|.| |
Zfish   286 EGSAAMISCTAEGEPLPEISW---RRASDGHS----------------FTDGEKSKDGRVEVR-G 330

  Fly   318 YRGVMLLVVRSFSPSDVGTYHCVSTNSLGRAEGTLRLYEIKLHP 361
            ..|..:|.:.....||.|.:.|.:.:.:|..:.::.| :|:..|
Zfish   331 RHGKSMLTISGVQLSDWGRFDCEALSRIGGHQKSMFL-DIEYAP 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	23/100 (23%)
		Ig	47..129	CDD:299845	19/83 (23%)
		Ig	140..238	CDD:299845	28/99 (28%)
		IG_like	247..355	CDD:214653	26/111 (23%)
		Ig	256..351	CDD:299845	24/96 (25%)
zgc:152904	NP_001070212.1	Ig	1..81	CDD:299845	4/19 (21%)
		IG_like	2..80	CDD:214653	4/18 (22%)
		IGc2	97..158	CDD:197706	19/73 (26%)
		Ig	177..273	CDD:299845	29/102 (28%)
		I-set	184..270	CDD:254352	26/92 (28%)
		Ig	272..369	CDD:299845	28/120 (23%)
		I-set	274..367	CDD:254352	27/115 (23%)
		IG_like	385..462	CDD:214653
		IGc2	386..454	CDD:197706
		FN3	468..561	CDD:238020
		fn3	<591..650	CDD:278470
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010