DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-gamma and igsf9bb

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	XP_009293693.1	Gene:	igsf9bb / 569554	ZFINID:	ZDB-GENE-091112-15	Length:	1439	Species:	Danio rerio

Alignment Length:	369	Identity:	93/369 - (25%)
Similarity:	137/369 - (37%)	Gaps:	93/369 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 STQNQHHESSSQLDPDPEFIGFINNVTYPAGREAILACSV---RNLGKNKVGWLRASDQTVLALQ 84
            ||:....:.:..:..:|:|      ||..||...||.|.|   .|.....|.|.:........:
Zfish    14 STRGTAAQGAHGVREEPQF------VTSRAGETVILGCDVVHPLNGQPYVVEWFKFGVPIPFFI- 71

  Fly    85 GRVVTHNARISVMHQD--------MH-TWKLKISKLRESDRGCYMCQI-----------NTSPMK 129
                  |.|....|.|        :| ...|:|.::|..|:|.|.|::           |.|.:.
Zfish    72 ------NFRFYPPHVDPEYAGRASLHGKSSLRIERVRSEDQGWYECKVLMLEQQYHTFHNGSWVH 130

  Fly   130 KQVGCIDVQVPPDIINEESSADLAVQEGEDATLTCKATGNPQPRVTWRREDGEMILIRKPGSREL 194
                 :.|..|| ...:.....:..:||...||:|.|.|||:|.|:|.||...:        ::.
Zfish   131 -----LTVNAPP-TFTDTPPQYVEAKEGGSITLSCTAFGNPKPSVSWLREGNPV--------QDS 181

  Fly   195 MKVESYNGSSLRLLRLERRQMGAYLCIASNDVPPAVSKRVSLSVQFAPMVRAPSQLLGTPLGSDV 259
            .|.:..:| ||.|:.:.|...|||.|.|.::...|| ....|.||..|.:.:|.:.:...:..|.
Zfish   182 TKYKVSDG-SLTLVSISREDRGAYTCRAYSEQGEAV-HTTRLLVQGPPFIVSPPENITVNISQDA 244

  Fly   260 QLECQVEASPSPVSY---WLKGARTSNGFASVSTASLESGSPGPEMLLDGPKYGITERRDGYRGV 321
            ...||.||.|..::|   |    ...|.|.........|      :|:||.
Zfish   245 FFTCQAEAYPGNLTYTWFW----EEDNVFFKNDLKRRVS------ILIDGS-------------- 285

  Fly   322 MLLVVRSFSPSDVGTYHCVSTNSLGRAEGTLRLYEIKLHPGASA 365
              |::....|.|.|.|.|..:|||||.            |.|||
Zfish   286 --LIISQVKPEDAGKYTCSPSNSLGRP------------PSASA 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	26/114 (23%)
		Ig	47..129	CDD:299845	25/104 (24%)
		Ig	140..238	CDD:299845	30/97 (31%)
		IG_like	247..355	CDD:214653	26/110 (24%)
		Ig	256..351	CDD:299845	25/97 (26%)
igsf9bb	XP_009293693.1	IG_like	30..113	CDD:214653	25/95 (26%)
		Ig	41..113	CDD:143165	19/78 (24%)
		IG_like	144..223	CDD:214653	28/88 (32%)
		IGc2	151..208	CDD:197706	24/65 (37%)
		I-set	227..319	CDD:254352	31/127 (24%)
		Ig	<263..319	CDD:299845	22/91 (24%)
		Ig_2	326..414	CDD:290606
		IG_like	329..403	CDD:214653
		IG_like	424..504	CDD:214653
		Ig	440..504	CDD:299845
		FN3	509..604	CDD:238020
		FN3	620..704	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010