DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-gamma and dscama

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	XP_021334866.1	Gene:	dscama / 568643	ZFINID:	ZDB-GENE-050310-7	Length:	2025	Species:	Danio rerio

Alignment Length:	322	Identity:	79/322 - (24%)
Similarity:	128/322 - (39%)	Gaps:	35/322 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 PEFIGFINNVTYPAGREAILACSVRNLGKNKVG--WLRASDQTVLALQGRVVTHNARISVMHQDM 101
            |.||.......|..|....:.|.||: |...:.  |.:         .|:.:..:..:::.:.|.
Zfish   597 PPFIQPFEFPRYSIGHRVFVPCVVRS-GDLPISITWEK---------DGKSINASLGVTIDNIDF 651

  Fly   102 HTWKLKISKLRESDRGCYMC--QINTSPMKKQVGCIDVQVPPDIINEESSADLAVQEGEDATLTC 164
             |..|:||.|:....|.|.|  |.:.:.:|.|...| |:|||....:....|...  |:...|.|
Zfish   652 -TSSLRISNLQRVHNGTYTCIAQNDAAVVKYQSQLI-VRVPPRFKVQPQDQDGIY--GKSVILNC 712

  Fly   165 KATGNPQPRVTWRREDGEMILIRKP-GSRELMKVESYNGSSLRLLRLERRQMGAYLCIASNDVPP 228
            .|.|.|:|.:.|:...|..:...:| ......:|:.....||.:..:.....|.|||..||||..
Zfish   713 SADGEPRPTIEWKYSKGAGVPQFQPIALNSGFRVQLLGNGSLLIKHVLEEDAGYYLCKVSNDVGA 777

  Fly   229 AVSKRVSLSVQFAPMVRA-PSQLLGTPLGSDVQLECQVEASPSPVSYWLKGARTSNGFASVSTAS 292
            .|||.:.|:|:...|:.: |:..|.|. |..:::.|:.......:..|.|......
Zfish   778 DVSKSMYLNVKIPAMITSYPNNSLATK-GEKIEMSCKAHGEKPIMVRWEKEVEKEK--------- 832

  Fly   293 LESGSPGPEMLLDGPKYGITERRDGYRGVMLLVVRSFSPSDVGTYHCVSTNSLGRAEGTLRL 354
             :|....|:|.    ::.:|.:..|...|..|.:......|.|.:.|.:.||.|...|.|:|
Zfish   833 -QSHMINPDMW----RHTVTVKNVGDEVVSTLQIYPTMREDSGFFSCHAINSYGEDRGILQL 889

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	22/95 (23%)
		Ig	47..129	CDD:299845	18/85 (21%)
		Ig	140..238	CDD:299845	28/98 (29%)
		IG_like	247..355	CDD:214653	23/108 (21%)
		Ig	256..351	CDD:299845	17/94 (18%)
dscama	XP_021334866.1	Ig	124..217	CDD:325142
		I-set	236..311	CDD:254352
		IG_like	321..402	CDD:214653
		I-set	408..502	CDD:333254
		IGc2	524..579	CDD:197706
		Ig	614..679	CDD:319273	16/75 (21%)
		Ig_DSCAM	708..787	CDD:143211	24/78 (31%)
		Ig	805..898	CDD:325142	20/99 (20%)
		FN3	894..988	CDD:238020
		FN3	995..1092	CDD:238020
		fn3	1100..1186	CDD:306538
		fn3	1199..1282	CDD:306538
		Ig	1312..1377	CDD:319273
		fn3	1405..1471	CDD:306538
		FN3	1492..1563	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810