DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-gamma and igsf9ba

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	XP_009289969.2	Gene:	igsf9ba / 567389	ZFINID:	ZDB-GENE-060503-729	Length:	1475	Species:	Danio rerio

Alignment Length:	365	Identity:	86/365 - (23%)
Similarity:	137/365 - (37%)	Gaps:	83/365 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 STQNQHHESSSQLDPDPEFIGFINNVTYPAGREAILACSVRNLGKNK-----VGWLRASDQTVLA 82
            ||:....:.:..:..:|:|      ||..||...:|.|.|.:....:     |.|.:........
Zfish    14 STRGTAAQGAHGVREEPQF------VTARAGESVVLGCDVSHPLNGQQTPYVVEWFKFGVPIPFF 72

  Fly    83 LQGRVVTHNARISVMHQD--------MH-TWKLKISKLRESDRGCYMCQINTSPMKKQVGC---- 134
            :       |.|....|.|        :| ...|:|.::|..|:|.|.|::  ..:::|...
Zfish    73 I-------NFRFYPPHVDPEYAGRASLHGKASLQIEQVRSEDQGWYECRV--LMLEQQYDTFHNG 128

  Fly   135 ----IDVQVPPDIINEESSADLAVQEGEDATLTCKATGNPQPRVTWRREDGEMILIRKPGSRELM 195
                :.|..|| ..::.....:..:||...||||.|.|||:|.|||.||..::...||
Zfish   129 SWVHLTVNAPP-TFSDTPPQYVEAREGGSITLTCTAFGNPKPVVTWLREGDQLTSTRK------- 185

  Fly   196 KVESYNGSSLRLLRLERRQMGAYLCIASNDVPPAVSKRVSLSVQFAPMVRAPSQLLGTPLGSDVQ 260
              .:.:..||.:..:.|...|||.|.|.:|...|: ....|.||..|.:..|.:.:...:..:.|
Zfish   186 --YTVSDGSLTVQAITREDRGAYSCRAHSDQGEAL-HTTRLLVQGPPYIVTPPENITVNISQNAQ 247

  Fly   261 LECQVEASPSPVSYWLKGARTSNGFASVSTASLESGSPGPEMLLDGPKYGITERRDGYRGVMLLV 325
            ..||.||.|..::|.......:..|.:.....:       .:.:||                .|:
Zfish   248 FTCQAEAYPGNLTYTWYWEEDNVYFKNDLKLRV-------RIFIDG----------------TLI 289

  Fly   326 VRSFSPSDVGTYHCVSTNSLGRAEGTLRLYEIKLHPGASA 365
            :....|.|.|.|.|..:||||            :.|.|||
Zfish   290 IYRVKPEDAGKYTCSPSNSLG------------ISPSASA 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	23/113 (20%)
		Ig	47..129	CDD:299845	21/95 (22%)
		Ig	140..238	CDD:299845	31/97 (32%)
		IG_like	247..355	CDD:214653	21/107 (20%)
		Ig	256..351	CDD:299845	20/94 (21%)
igsf9ba	XP_009289969.2	IG	30..115	CDD:214652	23/97 (24%)
		I-set	139..225	CDD:254352	30/96 (31%)
		I-set	229..321	CDD:333254	26/124 (21%)
		Ig	345..415	CDD:325142
		Ig	438..503	CDD:319273
		FN3	511..606	CDD:238020
		FN3	622..706	CDD:238020
		Atrophin-1	<924..1361	CDD:331285
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810