DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-gamma and sdk1a

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	XP_009297968.1	Gene:	sdk1a / 558391	ZFINID:	ZDB-GENE-081104-374	Length:	2245	Species:	Danio rerio

Alignment Length:	342	Identity:	86/342 - (25%)
Similarity:	128/342 - (37%)	Gaps:	93/342 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 FINN---VTYPAGREAIL-ACSVRNLGKNKVGWLRASDQTVLALQGRVVTHNARISVMHQDMHTW 104
            ||:|   .|...||.||| :.:|....:.:|.|.|         .|..:..:.||::..::
Zfish   214 FIDNDQRKTVTQGRAAILNSPAVSCFPRPQVTWFR---------DGYKIIPSNRIAITLEN---- 265

  Fly   105 KLKISKLRESDRGCYMCQ----------------INTSPMKKQVGCIDVQVPPD------IINEE 147
            :|.:.....||.|.|..|                :|.:..||..|..|.:.|.|      :|...
Zfish   266 QLVVLGTAASDAGRYYVQAVNEKNGENKTSPSIYLNVAANKKYRGSHDSEAPADPVAPVIVIPPR 330

  Fly   148 SSADLAVQEG-EDATLTCKATGNPQPRVT--WRREDGEMILIRKPGSRELMKVESYNGSSLRLLR 209
            ::..:|   | .:|||.|.|...|..:::  |||..              ::|.|..||..|.|.
Zfish   331 NTTVVA---GISEATLECVANARPVEKLSLVWRRNG--------------VEVASGVGSFSRRLT 378

  Fly   210 L---ERRQMGAYLC---IASNDVPPAVSKRVSLSVQFAPMVRA-PSQLLGTPLGSDVQLECQVEA 267
            :   ....:|.|:|   :..:.|.|| ..|..||:..||...| |.:.:...:...|.::||...
Zfish   379 IINPTSTDVGMYVCEALLLDSSVKPA-EARAFLSITEAPYFTAEPRRKMMGEVEKSVDIQCQARG 442

  Fly   268 SPSPVSYWLKGARTSNGFASVSTASLESGSPGPEMLLDGPKYGITERRDGYRGVMLLVVRSFSPS 332
            .|.|...|.|.|                   .|...|:.|:|.|...       |.|.||...||
Zfish   443 VPMPKLEWYKDA-------------------VPLSKLNNPRYKIISS-------MGLQVRKLQPS 481

  Fly   333 DVGTYHCVSTNSLGRAE 349
            |.|.:.|.:.||.|.|:
Zfish   482 DAGIFQCFARNSAGEAQ 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	25/111 (23%)
		Ig	47..129	CDD:299845	21/101 (21%)
		Ig	140..238	CDD:299845	28/112 (25%)
		IG_like	247..355	CDD:214653	27/103 (26%)
		Ig	256..351	CDD:299845	26/94 (28%)
sdk1a	XP_009297968.1	I-set	125..208	CDD:254352
		Ig	125..204	CDD:299845
		IG_like	222..302	CDD:214653	19/92 (21%)
		Ig	236..287	CDD:299845	13/63 (21%)
		Ig_3	322..394	CDD:290638	21/88 (24%)
		I-set	323..412	CDD:254352	26/106 (25%)
		I-set	416..505	CDD:254352	29/109 (27%)
		Ig	436..500	CDD:299845	25/89 (28%)
		I-set	510..600	CDD:254352
		Ig	527..600	CDD:299845
		I-set	605..693	CDD:254352
		Ig	610..693	CDD:299845
		FN3	697..788	CDD:238020
		fn3	800..886	CDD:278470
		FN3	901..997	CDD:238020
		FN3	1002..1090	CDD:238020
		FN3	1100..1196	CDD:238020
		FN3	1206..1301	CDD:238020
		FN3	1308..1397	CDD:238020
		FN3	1408..1501	CDD:238020
		FN3	1507..1602	CDD:238020
		FN3	1616..1722	CDD:238020
		FN3	1732..1825	CDD:238020
		FN3	1830..1919	CDD:238020
		FN3	1931..2021	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810