DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-gamma and igsf9a

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	XP_005155702.1	Gene:	igsf9a / 557459	ZFINID:	ZDB-GENE-060503-288	Length:	1619	Species:	Danio rerio

Alignment Length:	329	Identity:	85/329 - (25%)
Similarity:	133/329 - (40%)	Gaps:	70/329 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 AILACSVRNLGKNK------VGWLRASDQTVLALQGRV-----VTHNARISVMHQDMHTWKLKIS 109
            |:|.||:....|:.      :.|:|....|.:.:|..|     ..::.|:|:....    .|::|
Zfish    37 AVLPCSLPAPQKDSSASQYVIEWVRQGFDTPIFMQLGVHPRVHPDYDGRVSLFGGT----SLQMS 97

  Fly   110 KLRESDRGCYMCQI----NTSPMKKQVGC---IDVQVPPDIINEESSADLAVQEGEDATLTCKAT 167
            .|:..|.|.|.|:|    .|:......|.   :.|..|| ::.|.|..::.|..|...||.|.|.
Zfish    98 GLQLEDEGWYECRILPLDQTTEEAGSSGSWTRLSVTAPP-VLTETSPPEVEVFVGRSLTLKCAAQ 161

  Fly   168 GNPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLRLLRLERRQMGAYLCIASNDVPPAVSK 232
            |||:|.:||.: ||..|   ||..    ||:..|| |:....:.|...|.|.|..||....| :.
Zfish   162 GNPRPTITWSK-DGAPI---KPQH----KVKMVNG-SVSFHAVSREAAGQYQCYTSNSEGNA-TH 216

  Fly   233 RVSLSVQFAPMVRAPSQLLGTPLGSDVQLECQVEASPSPVSY-WLKGARTSNGFASVSTASLESG 296
            ...|.:...|::..|.......:..|.:|:||.||.|..::| |.:        ..|....::|.
Zfish   217 VTRLKIIGPPVIIIPPSDTVLNMSQDAKLKCQAEADPPNMTYVWQR--------QGVDIYHIDSL 273

  Fly   297 SPGPEMLLDGPKYGITERRDGYRGVMLLVVRSFSPSDVGTYHCVSTNSLGRAEGTLRLYEIKLHP 361
            ....::::||                .|::...:|.|.|.|.|:.||.|            .:.|
Zfish   274 KSRIKVIVDG----------------TLLISRLAPEDSGNYTCMPTNGL------------PVSP 310

  Fly   362 GASA 365
            .|||
Zfish   311 SASA 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	23/100 (23%)
		Ig	47..129	CDD:299845	21/87 (24%)
		Ig	140..238	CDD:299845	34/97 (35%)
		IG_like	247..355	CDD:214653	23/108 (21%)
		Ig	256..351	CDD:299845	22/95 (23%)
igsf9a	XP_005155702.1	IG_like	27..110	CDD:214653	18/76 (24%)
		Ig	35..111	CDD:299845	19/77 (25%)
		I-set	140..221	CDD:254352	31/90 (34%)
		IGc2	151..212	CDD:197706	27/69 (39%)
		Ig	233..318	CDD:299845	26/118 (22%)
		I-set	233..318	CDD:254352	26/118 (22%)
		Ig	<349..402	CDD:299845
		IG_like	423..502	CDD:214653
		Ig	435..498	CDD:143165
		FN3	507..602	CDD:238020
		fn3	614..696	CDD:278470
		PHA02666	1105..>1312	CDD:222914
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900