Protein Alignment DIP-gamma and OPCML

DIOPT Version :10

• Sequence 1: NP_651649.1
• Gene: DIP-gamma / 43417
• FlyBaseID: FBgn0039617
• Length: 413
• Species: Drosophila melanogaster
• Sequence 2: NP_001306032.1
• Gene: OPCML / 4978
• HGNCID: 8143
• Length: 354
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 101/358 - (28%)
• Similarity: 152/358 - (42%)
• Gaps: 54/358 - (15%)

  Fly    38 DPEFIGFINNVTYPAGREAILACSVRNLGKNKVGWLRASDQTVLALQGRVVTHNARISVMHQDMH 102
            |..|...::|||...|..|.|.|::.: ...:|.||..|  |:|.......:.:.|:.::.....
Human    35 DATFPKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRS--TILYAGNDKWSIDPRVIILVNTPT 96

  Fly   103 TWKLKISKLRESDRGCYMCQINTS--PMKKQVGCIDVQVPPDIINEESSADLAVQEGEDATLTCK 165
            .:.:.|..:...|.|.|.|.:.|.  |...:|..| |||||.|:|  .|:|:.|.||...||.|.
Human    97 QYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIMN--ISSDITVNEGSSVTLLCL 158

  Fly   166 ATGNPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLRLLRLERRQMGAYLCIASNDVPPAV 230
            |.|.|:|.||||.      |..|.| :..:..:.|    |.:..::|.|.|.|.|.|.|||....
Human   159 AIGRPEPTVTWRH------LSVKEG-QGFVSEDEY----LEISDIKRDQSGEYECSALNDVAAPD 212

  Fly   231 SKRVSLSVQFAPMVRAPSQLLGTPLGSDVQLECQVEASPSPVSYWLKGARTSNGFASVSTASLES 295
            .::|.::|.:.|.: :.::..|..:|....|.|:..|.|.....|.|           ....|.:
Human   213 VRKVKITVNYPPYI-SKAKNTGVSVGQKGILSCEASAVPMAEFQWFK-----------EETRLAT 265

  Fly   296 GSPGPEMLLDGPKYGITERRDGYRGVM-LLVVRSFSPSDVGTYHCVSTNSLGRAEGTLRLYEIKL 359
            |       |||       .|...:|.| .|...:.|..|.|.|.||:||.||....::.||||.
Human   266 G-------LDG-------MRIENKGRMSTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYEIS- 315

  Fly   360 HPGASASNDDHLNYIGGLEEAARNAGRSNRTTW 392
             |.::.:..      |.:.:...:|.|:....|
Human   316 -PSSAVAGP------GAVIDGVNSASRALACLW 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	Ig	47..129	CDD:472250	21/83 (25%)
		Ig strand B	56..60	CDD:409353	2/3 (67%)
		Ig strand C	69..73	CDD:409353	1/3 (33%)
		Ig strand E	104..108	CDD:409353	0/3 (0%)
		Ig strand F	118..123	CDD:409353	2/4 (50%)
		Ig	141..238	CDD:472250	34/96 (35%)
		Ig strand B	160..164	CDD:409562	2/3 (67%)
		Ig strand C	173..177	CDD:409562	2/3 (67%)
		Ig strand E	203..207	CDD:409562	1/3 (33%)
		Ig strand F	217..222	CDD:409562	2/4 (50%)
		Ig strand G	231..234	CDD:409562	0/2 (0%)
		IG_like	247..355	CDD:214653	27/108 (25%)
		Ig strand B	259..263	CDD:409358	1/3 (33%)
		Ig strand C	272..276	CDD:409358	0/3 (0%)
		Ig strand E	317..326	CDD:409358	3/9 (33%)
		Ig strand F	336..341	CDD:409358	2/4 (50%)
OPCML	NP_001306032.1	Ig	44..132	CDD:472250	23/91 (25%)
		Ig strand B	53..57	CDD:409353	2/3 (67%)
		Ig strand C	65..69	CDD:409353	1/3 (33%)
		Ig strand E	98..102	CDD:409353	0/3 (0%)
		Ig strand F	112..117	CDD:409353	2/4 (50%)
		Ig strand G	125..128	CDD:409353	0/2 (0%)
		Ig_3	135..206	CDD:464046	31/83 (37%)
		Ig	224..312	CDD:472250	28/113 (25%)
		Ig strand B	240..244	CDD:409353	1/3 (33%)
		Ig strand C	253..257	CDD:409353	0/3 (0%)
		Ig strand E	279..283	CDD:409353	1/3 (33%)
		Ig strand F	293..298	CDD:409353	2/4 (50%)
		Ig strand G	306..309	CDD:409353	0/2 (0%)