DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-gamma and CG7166

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	393	Identity:	104/393 - (26%)
Similarity:	160/393 - (40%)	Gaps:	92/393 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 DPD---PEFI--GFINNVTYPAGREAILACSVRNLGKNKVGWLRASDQTVLALQGRVVTHNARIS 95
            ||.   |:|:  |.:..|.  .|....|.|.|:|||...:.|.:.|  :||......:|.:.|..
  Fly    33 DPPTTAPKFLSRGHLYKVI--VGETIELPCKVQNLGSFVLLWRKGS--SVLTAGHLKITRDQRFK 93

  Fly    96 VMHQDMHTWKLKISKLRESDRGCYMCQINTSPMKKQVGCIDVQVPPDIINEESSADLAVQEGEDA 160
            ::..    :.|:|:.::..|.|.|:||:.....:.||..:::.|||.:.....:..:..::|...
  Fly    94 IVGD----YNLQINGVKTQDAGDYICQLGDQENRDQVHTVEILVPPTLRALPHNGQVTARKGSTV 154

  Fly   161 TLTCKATGNPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLRLLRLERRQMGAYLCIASND 225
            ||.|||:|||.|.:.|.::|    :...|       ....:.|:|.|..::|...|.|.|.|.|.
  Fly   155 TLECKASGNPVPTIFWFKKD----VFSGP-------THLSDSSTLILENVDRHHAGTYQCSADNG 208

  Fly   226 VPPAVSKRVSLSVQFAPMVRAPSQLLGTPLGSDVQLECQVEASPSPVSYWLKGARTSNGFASVST 290
            |...||..:.|::...|.:......:....|.||:|.|.|....:....|.:     |.|
  Fly   209 VKDRVSMDIQLTILSPPEITVEKSWVHASEGYDVELVCIVHGDVNSEMLWYQ-----NSF----- 263

  Fly   291 ASLESGSPGPEMLLDGPKYGITERR------DGYRGVMLLVVRSFSPSDVGTYHCVSTNSLGRAE 349
                        |||.     |:||      |.|.    |::|:|.|:|.|.|.||:.|:|||
  Fly   264 ------------LLDA-----TDRRSMYPRDDRYS----LIIRNFQPTDFGNYSCVADNALGR-- 305

  Fly   350 GTLRLYEIKLHPG-------ASASNDDHLNYIGGLEEAARNAGRSNRTTWQ----PLLAMLMLLW 403
             |.:..|:...||       |.:...||.|                 .||.    |.|..:.||:
  Fly   306 -TKKYIEVSGRPGPADFISPALSGFLDHYN-----------------LTWTIESIPPLDEIKLLY 352

  Fly   404 MRL 406
            .||
  Fly   353 RRL 355

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	23/91 (25%)
		Ig	47..129	CDD:299845	21/81 (26%)
		Ig	140..238	CDD:299845	28/97 (29%)
		IG_like	247..355	CDD:214653	31/113 (27%)
		Ig	256..351	CDD:299845	30/100 (30%)
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	23/90 (26%)
		Ig	56..116	CDD:143165	17/65 (26%)
		IG_like	144..221	CDD:214653	26/87 (30%)
		IGc2	151..209	CDD:197706	22/68 (32%)
		IG_like	232..313	CDD:214653	32/114 (28%)
		Ig	242..311	CDD:143165	29/102 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
	3	2.810