DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-gamma and ImpL2

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster

Alignment Length:	231	Identity:	44/231 - (19%)
Similarity:	87/231 - (37%)	Gaps:	63/231 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   154 VQEGEDAT--LTCKATGNPQPRVTW------RRE----DGEMILIRKPGSRELMKVESYNGSSLR 206
            :|:.:.||  :.|:..|:..|.:.|      |.|    |...:....|.:  :::|.|.:
  Fly    68 LQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSA--IVRVRSSH----- 125

  Fly   207 LLRLERRQMGAYLCI---------ASNDVPPAVSKRVSLSVQFAPMVRAPSQLLGTP------LG 256
            ::.....:...|.|:         ||..|.|..|.|::....: |..:.| :::.|.      :|
  Fly   126 IIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTY-PGAQKP-RIIYTEKTHLDLMG 188

  Fly   257 SDVQLECQVEASPSPVSYWLKGARTSNGFASVSTASLESGSPGPEMLLDGPKYGITERRDGYRGV 321
            |::||.|:|.|.|.....||....                    :.::.|.::.:....|
  Fly   189 SNIQLPCRVHARPRAEITWLNNEN--------------------KEIVQGHRHRVLANGD----- 228

  Fly   322 MLLVVRSFSPSDVGTYHCVSTNSLGRAEGTLRLYEI 357
              |::......|:|.|.|::.|.:|:......:|.:
  Fly   229 --LLISEIKWEDMGNYKCIARNVVGKDTADTFVYPV 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653
		Ig	47..129	CDD:299845
		Ig	140..238	CDD:299845	21/104 (20%)
		IG_like	247..355	CDD:214653	21/113 (19%)
		Ig	256..351	CDD:299845	19/94 (20%)
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	18/90 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900