DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DIP-gamma and wrapper

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	320	Identity:	93/320 - (29%)
Similarity:	140/320 - (43%)	Gaps:	64/320 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 LKISKLRESDRGCYMCQINT-SPMKKQVGCIDVQVPPDIINEESSADLAVQE-GEDATLTCKATG 168
            |:::.::.||.|.|.|::|: |....|...|:||:.|.::.|.|  ||..|. |....:.|:|.|
  Fly    96 LQVANVQSSDTGDYYCEMNSDSGHVVQQHAIEVQLAPQVLIEPS--DLTEQRIGAIFEVVCEAQG 158

  Fly   169 NPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLRLLRLERRQMGAYLCIASNDV-PPAVSK 232
            .|||.:|||. :|.:|   :|.|      .:.|..||.|....|.|.|...|:|||.| .|||:
  Fly   159 VPQPVITWRL-NGNVI---QPQS------NTGNRQSLILEIKSRNQAGLIECVASNGVGEPAVA- 212

  Fly   233 RVSLSVQFAPMVRAPSQLLGTPLGSDVQLECQVEASPSPVSYWLK-------GARTSNGFASVST 290
            .|.|.|.|:|.|..|..::.|.|||...|||.|||:|:....|..       ||.::...:.:.|
  Fly   213 NVYLHVLFSPEVSIPQPVVYTKLGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTTHESELQT 277

  Fly   291 ASLESGSPGPEMLLDGPKYGITERRDGYRGVM--LLVVRSFSPSDVGTYHCVSTNSLGRAEGTLR 353
                                 ....|.|...:  :|||:|...:|:|.|.|.::|.:....|::.
  Fly   278 ---------------------NRSVDHYVNAVRHMLVVKSVRNADMGQYECRASNQISVKSGSVE 321

  Fly   354 LYE------IKLHPGASASNDDHLNY------------IGGLEEAARNAGRSNRTTWQPL 395
            |..      .|::||..:|....|.:            :...:..:.|..|..||.|..|
  Fly   322 LTGRPMPCLFKINPGTQSSTSHVLVWQTESLLPIMEFKLKFRQIPSNNVTRQVRTNWTEL 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	11/33 (33%)
		Ig	47..129	CDD:299845	8/23 (35%)
		Ig	140..238	CDD:299845	37/99 (37%)
		IG_like	247..355	CDD:214653	28/116 (24%)
		Ig	256..351	CDD:299845	24/103 (23%)
wrapper	NP_477404.1	Ig	41..124	CDD:299845	9/27 (33%)
		IG_like	41..118	CDD:214653	7/21 (33%)
		IG_like	145..218	CDD:214653	31/83 (37%)
		Ig	147..219	CDD:299845	31/82 (38%)
		I-set	224..323	CDD:254352	29/119 (24%)
		IGc2	236..314	CDD:197706	24/98 (24%)
		FN3	339..431	CDD:238020	8/43 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810