DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-gamma and fipi

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_787975.1	Gene:	fipi / 33676	FlyBaseID:	FBgn0031627	Length:	450	Species:	Drosophila melanogaster

Alignment Length:	356	Identity:	78/356 - (21%)
Similarity:	126/356 - (35%)	Gaps:	99/356 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 HHESSSQLDPDPEFIGFINNVTYPAGREAILACSVRNLGKNKVGWLRASDQTV----LALQGRVV 88
            ||||.|....:...:.:.|       ...|:.|             |:.|..|    .:.:|.::
  Fly    21 HHESLSLSPAEHSVVRYTN-------ESLIVQC-------------RSPDPKVELHWKSPKGEII 65

  Fly    89 -THNARISVMHQDMHTWKLKISKLRESDRGCYMCQINTSPMKKQVGCIDVQVPPDIINEESSADL 152
             .|..||.:........|:..:.:..:|:|.:.|:.....:..:  ..|:.|...|...|::..:
  Fly    66 REHKGRIHIEQTSTEQLKIVFAHIALADKGNWSCEAADGSLHSK--SFDLIVYQKITFTENATVM 128

  Fly   153 AVQEGEDATLTCKATGNPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLRLL-------RL 210
            .|:|||.||:.|:..|.|||.||| ..:|:.|           ...:.:.|..|:|       ::
  Fly   129 TVKEGEKATILCEVKGEPQPNVTW-HFNGQPI-----------SAGAADDSKFRILADGLLINKV 181

  Fly   211 ERRQMGAYLC-------IASN----------DVPPAVSKRVSLSVQFAPMVRAPSQLLGTPLGSD 258
            .:...|.|.|       |||:          :..|..||...:|:::|       .:.||
  Fly   182 TQNDTGEYACRAYQVNSIASDMQERTVLMKIEHKPIWSKTPFVSLKYA-------YINGT----- 234

  Fly   259 VQLECQVEASPSPVSYWLKGARTSNGFASVSTASLESGSPGPEMLLDGPKYGITERRDGYRGVML 323
            ..|.|:..|.|.....|.   |..|...|.:..                   .|.:.|.|...:.
  Fly   235 ATLMCEALAEPPANFTWY---RKHNKLHSNNRL-------------------YTIQSDSYWSSLT 277

  Fly   324 LVVRSFSPSDVGTYHCVSTNSLGRAEGTLRL 354
            :.|.:.|..|  .|.|.:.|.||..|.|.||
  Fly   278 IHVLNTSAFD--NYRCRARNDLGTIERTTRL 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	14/96 (15%)
		Ig	47..129	CDD:299845	13/86 (15%)
		Ig	140..238	CDD:299845	30/121 (25%)
		IG_like	247..355	CDD:214653	25/108 (23%)
		Ig	256..351	CDD:299845	20/94 (21%)
fipi	NP_787975.1	IG_like	33..115	CDD:214653	15/103 (15%)
		I-set	128..202	CDD:254352	24/85 (28%)
		Ig	133..>193	CDD:299845	20/71 (28%)
		IG_like	228..307	CDD:214653	26/115 (23%)
		Ig	235..305	CDD:143165	21/93 (23%)
		FN3	312..415	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12231
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.000