DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-gamma and CG33543

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001014458.3	Gene:	CG33543 / 3346207	FlyBaseID:	FBgn0053543	Length:	468	Species:	Drosophila melanogaster

Alignment Length:	349	Identity:	75/349 - (21%)
Similarity:	118/349 - (33%)	Gaps:	99/349 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 NVTYPAGREAILACSVRNLGKN-KVGWLRASDQTVLALQGRVVTHNARISVMHQDMHTWKLKISK 110
            ::|:......|:.|  :.:.|: ...|.....||....:|||........::       .|....
  Fly    56 SITHFVNESFIIFC--QTVQKDIDTKWRDPRGQTRENTKGRVHIEKKTTGLL-------ALVFEH 111

  Fly   111 LRESDRGCYMCQINTSPMKKQVGCIDVQVPPD-------IINEESSAD-----LAVQEGEDATLT 163
            :...|||.:.|::|.:    :.|..:|.|..:       ::|::.|..     .:|:||.||.:.
  Fly   112 IALEDRGNWTCEVNGN----RNGNRNVNVEREFLASFELLVNQKISFGKTEQVQSVREGRDAMVN 172

  Fly   164 CKATGNPQPRVTWRREDGEMILIRKPGSRELMKVESYN--GSSLRLLRLERRQMGAYLCIASNDV 226
            |...|.|.|.|:| ..:||.|        ..:....:|  .:.|.:..:.:...|.|.|.|....
  Fly   173 CFVEGMPAPEVSW-LYNGEYI--------NTVNSTKHNRLSNGLYIRNVSQADAGEYTCRAMRIT 228

  Fly   227 PP-------AVSKRV----------SLSVQFAPMVRAPSQLLGTPLGSDVQLECQVEASPSPVSY 274
            |.       .:..|:          :|.||:|            .:|..|.|.|.....|.|...
  Fly   229 PTFSDSDQITILLRIQHKPHWFFNETLPVQYA------------YVGGAVNLSCDAMGEPPPSFT 281

  Fly   275 WLKGARTSNGF-ASVSTASLESGSPGPEMLLDGPKYGITERRDGYRGVMLLVVRSFSPSDVGTYH 338
            ||...:...|| ..:..|.                ||.|           |.::..:.|..|.|.
  Fly   282 WLHNNKGIVGFNHRIFVAD----------------YGAT-----------LQLQMKNASQFGDYK 319

  Fly   339 CVSTNSLGRAEGTLRLYEIKLHPG 362
            |...|.||..|..     |||.||
  Fly   320 CKVANPLGMLERV-----IKLRPG 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	18/92 (20%)
		Ig	47..129	CDD:299845	16/82 (20%)
		Ig	140..238	CDD:299845	25/128 (20%)
		IG_like	247..355	CDD:214653	23/108 (21%)
		Ig	256..351	CDD:299845	23/95 (24%)
CG33543	NP_001014458.3	IGc2	165..224	CDD:197706	18/67 (27%)
		IG_like	256..336	CDD:214653	28/123 (23%)
		IGc2	263..327	CDD:197706	20/90 (22%)
		FN3	341..445	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12231
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.000