DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment DIP-gamma and Prtg

DIOPT Version :9

Sequence 1:NP_651649.1 Gene:DIP-gamma / 43417 FlyBaseID:FBgn0039617 Length:413 Species:Drosophila melanogaster
Sequence 2:NP_001032740.2 Gene:Prtg / 315806 RGDID:1307157 Length:1193 Species:Rattus norvegicus


Alignment Length:337 Identity:69/337 - (20%)
Similarity:120/337 - (35%) Gaps:73/337 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    51 PAGREAILACSVRNLGKNKVGWLRASDQTVLALQGRVVTHNARISVMHQDMHTWKLKISKLRESD 115
            |.|..|..:|.:.:.....:.|  ..::|.|.:     |.::|::.:...:    |:|......|
  Rat   141 PEGGVARFSCKISSTPPAVITW--EFNRTALPM-----TMDSRVTALPSGV----LQIYDAGPED 194

  Fly   116 RGCYMCQINTSPMKKQVGCIDVQVPPDIINE----------ESSADLAVQEGEDATLTCKATGNP 170
            .|.|.|...|...|::.....:.:.|  .||          .|..::.....:...|.|.|||.|
  Rat   195 AGKYRCVAATHAHKRKSMEASLTI
VP--ANETRSFYMPTIIASPQNVTASLHQTVVLECMATGYP 257

  Fly   171 QPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLRLLRLERRQMGAYLCIASNDVPPAVSKRVS 235
            :|.::|.|.|.:.|        ::.........:|.:..::.:..|.|:|.|:.   |. ::..:
  Rat   258 KPIISWSRLDHKSI--------DVFNTRVLGNGNLIISDVKLQHAGVYVCRATT---PG-TRNFT 310

  Fly   236 LSVQFAPMVRAPS-----QLLGTPLGSDVQLECQVEASPSPVSYWLKGART--SNGFASVSTASL 293
            :::....::..||     :.|..|.....:..||.|..|||...|||..|.  |||...:..:. 
  Rat   311 VAMATLTVLAPPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRRIHSNGRIKMYNSK- 374

  Fly   294 ESGSPGPEMLLDGPKYGITERRDGYRGVMLLVVRSFSPSDVGTYHCVSTNSLGRAEGTLRLYEIK 358
                                          ||:....|.|...|.|::.||.|......||..:.
  Rat   375 ------------------------------LVINQIIPEDDAIYQCMAENSQGSVLSRARLTVVM 409

  Fly   359 LHPGASASNDDH 370
            .....||..:.|
  Rat   410 SEDRPSAPYNVH 421

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-gammaNP_651649.1 IG_like 47..139 CDD:214653 17/87 (20%)
Ig 47..129 CDD:299845 16/77 (21%)
Ig 140..238 CDD:299845 21/107 (20%)
IG_like 247..355 CDD:214653 27/114 (24%)
Ig 256..351 CDD:299845 22/96 (23%)
PrtgNP_001032740.2 Ig 32..124 CDD:416386
Ig strand A 32..35 CDD:409353
Ig strand A' 38..44 CDD:409353
Ig strand B 48..58 CDD:409353
Ig strand C 62..68 CDD:409353
Ig strand C' 70..73 CDD:409353
Ig strand D 78..83 CDD:409353
Ig strand E 85..91 CDD:409353
Ig strand F 103..110 CDD:409353
Ig strand G 114..124 CDD:409353
Ig 131..218 CDD:416386 17/87 (20%)
Ig strand B 146..150 CDD:409353 1/3 (33%)
Ig strand C 159..163 CDD:409353 1/5 (20%)
Ig strand E 183..187 CDD:409353 1/7 (14%)
Ig strand F 197..202 CDD:409353 2/4 (50%)
Ig strand G 211..214 CDD:409353 0/2 (0%)
Ig_3 230..302 CDD:404760 16/79 (20%)
Ig strand B 247..251 CDD:409353 1/3 (33%)
Ig strand C 260..264 CDD:409353 0/3 (0%)
Ig strand E 282..286 CDD:409353 1/3 (33%)
Ig strand F 296..301 CDD:409353 2/4 (50%)
I-set 322..407 CDD:400151 28/115 (24%)
Ig strand C 352..357 CDD:409353 1/4 (25%)
Ig strand C' 359..362 CDD:409353 1/2 (50%)
Ig strand D 367..371 CDD:409353 0/3 (0%)
Ig strand E 373..378 CDD:409353 2/35 (6%)
Ig strand F 387..394 CDD:409353 2/6 (33%)
Ig strand G 398..407 CDD:409353 2/8 (25%)
FN3 414..507 CDD:238020 3/8 (38%)
FN3 512..605 CDD:238020
fn3 619..694 CDD:394996
FN3 721..809 CDD:238020
FN3 816..906 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 974..1018
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1078..1193
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR12231
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.