DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-gamma and Dscaml1

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001101611.1	Gene:	Dscaml1 / 315615	RGDID:	1304887	Length:	2111	Species:	Rattus norvegicus

Alignment Length:	352	Identity:	78/352 - (22%)
Similarity:	130/352 - (36%)	Gaps:	74/352 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SGSTQNQHHESSSQLDPD---PEFIGFINNVTYPAGREAILACSVRNLGKNKVGWLRASDQTVLA 82
            ||.|:..:....|..||.   |..:...::.....|....|.|:........:.||:
  Rat   263 SGETRQSNGARLSVTDPAESIPTILDGFHSQEVWTGHAVELPCAASGYPIPAIRWLK-------- 319

  Fly    83 LQGRVVTHNARISVMHQDMHTWK-----LKISKLRESDRGCYMCQI-NTSPMKKQVGCIDVQVPP 141
             .||.:..::|          |.     |.||.||..|.|.|:|:: ||....:..|.:.|..|.
  Rat   320 -DGRPLPADSR----------WAKRITGLTISDLRTEDSGTYICEVTNTFGSAEANGVLTVIDPL 373

  Fly   142 DIINEESSADLAVQEGEDATLTCKATGNPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLR 206
            .:..........:  |....|:|..||:|:..:.|.| :.|::|   ||  |.:.:...:..:|.
  Rat   374 HVTLTPKKLKTGI--GSTVILSCALTGSPEFTIRWYR-NTELVL---PG--EAISIRGLSNETLL 430

  Fly   207 LLRLERRQMGAYLCIASNDVPPAVSKRVSLSVQFAP-MVRAPSQLLGTPLGSDVQLECQVEASPS 270
            :...::...|||.|.|:.....|....:.:.....| :|.:.|:.:..| |....|.|..:.:|.
  Rat   431 ISSAQKSHSGAYQCFATRKAQTAQDFAIIVLEDGTPRIVSSFSEKVVNP-GEQFSLMCAAKGAPP 494

  Fly   271 PVSYWL--------KGARTSNGFASVSTASLESGSPGPEMLLDGPKYGITERRDGYRGVMLLVVR 327
            |...|.        .|:..:|.:      ::..|:....|.:.||:.     |||
  Rat   495 PTVTWALDDEPVVRDGSHRTNQY------TMSDGTTISHMNVTGPQI-----RDG---------- 538

  Fly   328 SFSPSDVGTYHCVSTNSLGRAEGTLRL 354
                   |.|.|.:.||:|.||...|:
  Rat   539 -------GVYRCTARNSVGSAEYQARI 558

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	22/97 (23%)
		Ig	47..129	CDD:299845	20/87 (23%)
		Ig	140..238	CDD:299845	21/97 (22%)
		IG_like	247..355	CDD:214653	26/116 (22%)
		Ig	256..351	CDD:299845	23/102 (23%)
Dscaml1	NP_001101611.1	IG	101..173	CDD:214652
		IGc2	101..168	CDD:197706
		Ig	183..276	CDD:299845	3/12 (25%)
		IG_like	195..276	CDD:214653	3/12 (25%)
		I-set	291..369	CDD:254352	21/96 (22%)
		IGc2	298..359	CDD:197706	20/79 (25%)
		IGc2	386..447	CDD:197706	18/68 (26%)
		I-set	466..560	CDD:254352	28/122 (23%)
		Ig	466..556	CDD:299845	27/118 (23%)
		IGc2	577..635	CDD:197706
		IG_like	665..744	CDD:214653
		Ig	673..739	CDD:143165
		I-set	748..843	CDD:254352
		Ig7_DSCAM	765..843	CDD:143211
		I-set	849..942	CDD:254352
		Ig	861..949	CDD:299845
		FN3	945..1039	CDD:238020
		FN3	1046..1143	CDD:238020
		fn3	1151..1237	CDD:278470
		FN3	1249..1340	CDD:238020
		IGc2	1364..1428	CDD:197706
		FN3	1442..1532	CDD:238020
		FN3	1546..1618	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810