DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-gamma and sdk

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001284756.1	Gene:	sdk / 31017	FlyBaseID:	FBgn0021764	Length:	2265	Species:	Drosophila melanogaster

Alignment Length:	357	Identity:	81/357 - (22%)
Similarity:	146/357 - (40%)	Gaps:	92/357 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 AILAC-SVRNLGKNKVG-WLRASDQTV------LALQGRVVTHNARISVMHQDMHTWKLKISKLR 112
            |:..| ::...|:|... |||...:|.      || |.|::    |:...|..:.:  .|.|:..
  Fly   429 AMFQCLAINEAGENSASTWLRVKTKTAKNRVKRLA-QPRIL----RVRASHAGLGS--EKGSESG 486

  Fly   113 ESDRGCYMCQINTSPMKKQVGCIDVQVPPDIINEESSADLAVQEGEDATLTCKATGNPQPRVTWR 177
            .|||.... :..::|:        :::||.        ::...:|:|||::|:|.|:|.|.:||.
  Fly   487 SSDRRKEF-RFASAPI--------MELPPQ--------NVTALDGKDATISCRAVGSPNPNITWI 534

  Fly   178 REDGEMILIRKPGSRELMKVESYNGSSLRLLRLERRQMGAYLCIASNDVPPAVSKRVSLSVQFAP 242
            ..:.:::.|..       :|:......|.:..:.....|.|:|:.:|:. .:|.....|||
  Fly   535 YNETQLVDISS-------RVQILESGDLLISNIRSVDAGLYICVRANEA-GSVKGEAYLSV---- 587

  Fly   243 MVRAPSQLLGTP------LGSDVQLECQVEASPSPVSY---WLKGARTSNGFASVSTASLESGSP 298
            :||  :|::..|      ||....|:|:|.:.|| |.|   |.:..::|...::.....:::
  Fly   588 LVR--TQIIQPPVDTTVLLGLTATLQCKVSSDPS-VPYNIDWYREGQSSTPISNSQRIGVQA--- 646

  Fly   299 GPEMLLDGPKYGITERRDGYRGVMLLVVRSFSPSDVGTYHCVSTNSLGRAEGTLRLYEIKL-HPG 362
                             ||.     |.:::...||||:|.||.|:..|......||..|:| .|.
  Fly   647 -----------------DGQ-----LEIQAVRASDVGSYACVVTSPGGNETRAARLSVIELPFPP 689

  Fly   363 ASASNDDHLNYIGGLEEAARNAGRSNRTTWQP 394
            ::..          :|.......||...:|.|
  Fly   690 SNVK----------VERLPEPQQRSINVSWTP 711

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	20/90 (22%)
		Ig	47..129	CDD:299845	20/80 (25%)
		Ig	140..238	CDD:299845	22/97 (23%)
		IG_like	247..355	CDD:214653	26/116 (22%)
		Ig	256..351	CDD:299845	22/97 (23%)
sdk	NP_001284756.1	Ig	71..157	CDD:299845
		I-set	72..150	CDD:254352
		Ig	172..245	CDD:299845
		IG_like	280..356	CDD:214653
		Ig	280..343	CDD:299845
		IG_like	375..450	CDD:214653	6/20 (30%)
		Ig	378..447	CDD:143165	4/17 (24%)
		Ig	506..587	CDD:299845	21/96 (22%)
		IG_like	506..587	CDD:214653	21/96 (22%)
		I-set	592..682	CDD:254352	27/115 (23%)
		Ig	595..682	CDD:299845	26/112 (23%)
		FN3	686..789	CDD:238020	6/36 (17%)
		FN3	798..893	CDD:238020
		FN3	901..1005	CDD:238020
		fn3	1011..1094	CDD:278470
		FN3	1108..1202	CDD:238020
		FN3	1210..1308	CDD:238020
		fn3	1317..1402	CDD:278470
		FN3	1415..1507	CDD:238020
		FN3	1513..1608	CDD:238020
		fn3	1617..1708	CDD:278470
		FN3	1722..1823	CDD:238020
		FN3	1828..1920	CDD:238020
		FN3	1927..2016	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900