DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-gamma and igcm-2

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001362087.1	Gene:	igcm-2 / 180913	WormBaseID:	WBGene00020130	Length:	802	Species:	Caenorhabditis elegans

Alignment Length:	349	Identity:	85/349 - (24%)
Similarity:	123/349 - (35%)	Gaps:	100/349 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 AGREAILACSVR--NLGKNKVGWLRASDQTVLA------------LQGRVVTHNARISVMHQDMH 102
            ||....|.||:.  |.....:.| |...|.:|:            ||||:    ||...:...:|
Worm    27 AGAPITLPCSISLFNEESFSLDW-RKDGQLILSAFGQEQGHVTPTLQGRL----ARDGFLGITIH 86

  Fly   103 TWKLKISKLRESDRGCYMCQIN------TSPMKKQVGCIDVQVPPDIINEESSADLAVQEGEDAT 161
            :       :.:.|.|.|.|.:.      |.|.|.....:.|.|||.||:...:|.:..:.|.|..
Worm    87 S-------VTDGDAGVYQCIVTKFSKQPTRPEKGLSAKLVVNVPPVIISPSKNAIIHKKVGADLI 144

  Fly   162 LTCKATGNPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLRLLRLERRQMGAYLCIASNDV 226
            ..|||.|.|.|.:||.|  .|.|:...|              .|.|..||....|.|.|:|.|..
Worm   145 FECKAEGAPSPEITWSR--NEQIISTSP--------------VLTLSNLEEGDKGLYTCLAVNIE 193

  Fly   227 PPAVSKRVSLSVQFA--------PMVRAPSQLLGTPLGSDVQLECQVEASPSPVSY-WLKGAR-- 280
            ..:.|   |:.|:|.        |:.:...:      ||:|...|...|..:.:|| ||...:
Worm   194 GNSTS---SIDVRFTKATILDLIPLNKTVIE------GSNVFWHCHANAQATAISYSWLFEKKPI 249

  Fly   281 --TSNGFASVSTASLESGSPGPEMLLDGPKYGITERRDGYRGVMLLVVRSFSPSDVGTYHCVSTN 343
              ||.|..|    ::.||.                          |.::....||.|.|.|.:.|
Worm   250 KTTSLGLRS----NIRSGD--------------------------LSLQDVRKSDSGWYTCEAKN 284

  Fly   344 SLGRAEGTLRLYEIKLHPGASASN 367
            |.|....:.....:...|...:|:
Worm   285 SAGETTSSTAYLHVFYPPEPLSSH 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	25/106 (24%)
		Ig	47..129	CDD:299845	23/96 (24%)
		Ig	140..238	CDD:299845	30/97 (31%)
		IG_like	247..355	CDD:214653	24/112 (21%)
		Ig	256..351	CDD:299845	24/99 (24%)
igcm-2	NP_001362087.1	IG_like	23..101	CDD:214653	21/85 (25%)
		Ig	124..200	CDD:386229	28/94 (30%)
		IG_like	214..298	CDD:214653	25/119 (21%)
		Ig_3	309..371	CDD:372822	85/349 (24%)
		Ig	389..467	CDD:386229
		FN3	476..548	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810