DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-gamma and zig-8

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_499714.1	Gene:	zig-8 / 176732	WormBaseID:	WBGene00006985	Length:	268	Species:	Caenorhabditis elegans

Alignment Length:	232	Identity:	58/232 - (25%)
Similarity:	96/232 - (41%)	Gaps:	28/232 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 STLFVIL---IMATKCGSGSTQN----QHHESSSQLDPDPEFIGFINNVTYPAGREAILACSVRN 64
            |.:.|||   :.||  |.|:::.    ...|.|...:|....:..:      |...|.|.|||..
Worm     5 SNICVILFSFLYAT--GHGASEEVMACLRQERSRVENPSQTIVNVV------AENPAYLHCSVPP 61

  Fly    65 LGKNKVGWLRASDQTVLALQGRVVTHNARISVMHQDMHTWKLKISKLRESDRGCYMCQINTSPMK 129
            ..::::.|.|.||..:|....|..|.:.|..|..:..:.|.|.:.:..:.|.|||:|:||.....
Worm    62 DAEHEIAWTRVSDGALLTAGNRTFTRDPRWQVSKKSANIWVLNLRRAEQQDSGCYLCEINDKHNT 126

  Fly   130 KQVGCIDVQVP----PDIINEESSADLAVQEGEDATLTCKATGNPQPR----VTWRREDGEMILI 186
            .....:.|..|    |..:.::|:..:|...|::..|.|..|...:..    |.|.| ||..|..
Worm   127 VYAVYLKVLEPPLPSPSSLQKKSTKLMANMSGDEVVLNCTVTSTDKDEEVLDVVWTR-DGNTINF 190

  Fly   187 RKPGSRELMKVESYNGSSLRLLRLERRQM---GAYLC 220
            ... .:.::||:...|..:..:|:.:..|   |.|.|
Worm   191 NDT-EKYILKVKRDAGVVIETMRIRKATMEDDGNYAC 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	25/91 (27%)
		Ig	47..129	CDD:299845	24/81 (30%)
		Ig	140..238	CDD:299845	22/92 (24%)
		IG_like	247..355	CDD:214653
		Ig	256..351	CDD:299845
zig-8	NP_499714.1	IG_like	55..134	CDD:214653	22/78 (28%)
		Ig	55..129	CDD:143165	22/73 (30%)
		ig	158..229	CDD:278476	18/71 (25%)
		IG_like	158..227	CDD:214653	18/71 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810