DRSC/TRiP Functional Genomics Resources

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Protein Alignment DIP-gamma and Opcml

DIOPT Version :9

Sequence 1:NP_651649.1 Gene:DIP-gamma / 43417 FlyBaseID:FBgn0039617 Length:413 Species:Drosophila melanogaster
Sequence 2:XP_017450901.1 Gene:Opcml / 116597 RGDID:620635 Length:354 Species:Rattus norvegicus


Alignment Length:358 Identity:99/358 - (27%)
Similarity:151/358 - (42%) Gaps:54/358 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 DPEFIGFINNVTYPAGREAILACSVRNLGKNKVGWLRASDQTVLALQGRVVTHNARISVMHQDMH 102
            |..|...::|||...|..|.|.|::.: ...:|.||..|  |:|.......:.:.|:.::.....
  Rat    35 DATFPKAMDNVTVRQGESATLRCTIDD-RVTRVAWLNRS--TILYAGNDKWSIDPRVIILVNTPT 96

  Fly   103 TWKLKISKLRESDRGCYMCQINTS--PMKKQVGCIDVQVPPDIINEESSADLAVQEGEDATLTCK 165
            .:.:.|..:...|.|.|.|.:.|.  |...:|..| |||||.|:|  .|:|:.|.||...||.|.
  Rat    97 QYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLI-VQVPPQIMN--ISSDITVNEGSSVTLLCL 158

  Fly   166 ATGNPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLRLLRLERRQMGAYLCIASNDVPPAV 230
            |.|.|:|.||||.      |..|.| :..:..:.|    |.:..::|.|.|.|.|.|.|||....
  Rat   159 AIGRPEPTVTWRH------LSVKEG-QGFVSEDEY----LEISDIKRDQSGEYECSALNDVAAPD 212

  Fly   231 SKRVSLSVQFAPMVRAPSQLLGTPLGSDVQLECQVEASPSPVSYWLK-GARTSNGFASVSTASLE 294
            .::|.::|.:.|.: :.::..|..:|....|.|:..|.|.....|.| ..|.:.|          
  Rat   213 VRKVKITVNYPPYI-SKAKNTGVSVGQKGILSCEASAVPMAEFQWFKEDTRLATG---------- 266

  Fly   295 SGSPGPEMLLDGPKYGITERRDGYRGVMLLVVRSFSPSDVGTYHCVSTNSLGRAEGTLRLYEIKL 359
                     |||      .|.:....:..|...:.|..|.|.|.||:||.||....::.||||. 
  Rat   267 ---------LDG------VRIENKGRISTLTFFNVSEKDYGNYTCVATNKLGNTNASITLYEIS- 315

  Fly   360 HPGASASNDDHLNYIGGLEEAARNAGRSNRTTW 392
             |.::.:..      |.:.:...:|.|:....|
  Rat   316 -PSSAVAGP------GAVIDGVNSASRALACLW 341

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DIP-gammaNP_651649.1 IG_like 47..139 CDD:214653 24/93 (26%)
Ig 47..129 CDD:299845 21/83 (25%)
Ig 140..238 CDD:299845 35/97 (36%)
IG_like 247..355 CDD:214653 25/108 (23%)
Ig 256..351 CDD:299845 24/95 (25%)
OpcmlXP_017450901.1 Ig 44..132 CDD:416386 23/91 (25%)
Ig strand A' 44..49 CDD:409353 3/4 (75%)
Ig strand B 51..59 CDD:409353 3/7 (43%)
CDR1 59..63 CDD:409353 0/4 (0%)
FR2 64..70 CDD:409353 2/5 (40%)
Ig strand C 64..70 CDD:409353 2/5 (40%)
CDR2 71..83 CDD:409353 3/13 (23%)
Ig strand C' 72..76 CDD:409353 2/5 (40%)
Ig strand C' 80..83 CDD:409353 0/2 (0%)
FR3 84..118 CDD:409353 6/33 (18%)
Ig strand D 87..94 CDD:409353 1/6 (17%)
Ig strand E 97..103 CDD:409353 0/5 (0%)
Ig strand F 110..118 CDD:409353 3/7 (43%)
CDR3 119..123 CDD:409353 1/3 (33%)
Ig strand G 123..132 CDD:409353 3/9 (33%)
FR4 125..132 CDD:409353 2/7 (29%)
Ig_3 135..206 CDD:404760 31/83 (37%)
Ig strand A 135..138 CDD:409353 2/2 (100%)
Ig strand A' 144..148 CDD:409353 1/3 (33%)
Ig strand B 151..160 CDD:409353 3/8 (38%)
Ig strand C 165..170 CDD:409353 3/4 (75%)
Ig strand C' 171..174 CDD:409353 1/8 (13%)
Ig strand F 198..206 CDD:409353 4/7 (57%)
Ig_3 223..300 CDD:404760 22/102 (22%)
putative Ig strand A 224..230 CDD:409353 1/6 (17%)
Ig strand B 240..244 CDD:409353 1/3 (33%)
Ig strand C 253..257 CDD:409353 0/3 (0%)
Ig strand E 279..283 CDD:409353 1/3 (33%)
Ig strand F 293..298 CDD:409353 2/4 (50%)
Ig strand G 306..309 CDD:409353 0/2 (0%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 142 1.000 Inparanoid score I4382
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D265311at33208
OrthoFinder 1 1.000 - - FOG0000150
OrthoInspector 1 1.000 - - mtm8971
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 1 1.000 - - X97
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
87.870

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