DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-gamma and CD226

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001290547.1	Gene:	CD226 / 10666	HGNCID:	16961	Length:	336	Species:	Homo sapiens

Alignment Length:	148	Identity:	33/148 - (22%)
Similarity:	58/148 - (39%)	Gaps:	31/148 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 NVTYPAGREAILACSVRNLG-KNKVGWLR-ASDQTVLAL----QGRVV--THNARISVMHQDM-- 101
            :.:.|......|.|...::| ..:|.|.: .:.|..:|:    .|.|:  .:..|:..::..|
Human    24 HTSVPFAENMSLECVYPSMGILTQVEWFKIGTQQDSIAIFSPTHGMVIRKPYAERVYFLNSTMAS 88

  Fly   102 HTWKLKISKLRESDRGCYMCQINTSPMKK--------QVGCIDVQVPPDIINEESSADLAVQEGE 158
            :...|......|.|.|.|.|.:.|.|...        |....:..||       |::.:..:.|:
Human    89 NNMTLFFRNASEDDVGYYSCSLYTYPQGTWQKVIQVVQSDSFEAAVP-------SNSHIVSEPGK 146

  Fly   159 DATLTCKATGNPQPRVTW 176
            :.||||      ||::||
Human   147 NVTLTC------QPQMTW 158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	21/109 (19%)
		Ig	47..129	CDD:299845	20/91 (22%)
		Ig	140..238	CDD:299845	11/37 (30%)
		IG_like	247..355	CDD:214653
		Ig	256..351	CDD:299845
CD226	NP_001290547.1	Ig	31..127	CDD:299845	19/95 (20%)
		Ig	136..240	CDD:299845	10/29 (34%)
		IG_like	138..240	CDD:214653	9/27 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	297..316
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910