DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-gamma and iglon5

DIOPT Version :9

Sequence 1:	NP_651649.1	Gene:	DIP-gamma / 43417	FlyBaseID:	FBgn0039617	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	XP_002938252.1	Gene:	iglon5 / 100488314	XenbaseID:	XB-GENE-945713	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	341	Identity:	90/341 - (26%)
Similarity:	140/341 - (41%)	Gaps:	69/341 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 EFIGFINNVTYPAGREAILACSVRNLGKNKVGWLRASDQTVLALQGRVVTHNARISVMHQDMHTW 104
            ||:...:|.|...|..|.|:|.:.: ...:|.||..|:  :|.......:.::|:.::......:
Frog    28 EFVPPADNYTVSQGDNATLSCLIDD-KVTRVAWLNRSN--ILYAGKDKWSIDSRVQLLTNTKSEY 89

  Fly   105 KLKISKLRESDRGCYMCQINT--SPMKKQVGCIDVQVPPDIINEESSADLAVQEGEDATLTCKAT 167
            .:.|:.:..:|.|.|.|...|  .|...||..| ||||..|:|..||  :.|.||.:..|.|.|.
Frog    90 SIVITHVDVADEGLYTCSFQTEDKPHTSQVYLI-VQVPAKIVNISSS--VTVNEGSNVNLQCLAV 151

  Fly   168 GNPQPRVTWRREDGEMILIRKPGSRELMKVESYNGSSLRLLRLERRQMGAYLCIASNDVPPAVSK 232
            |.|:|.:||               ::|.:..|..|..|.:..:.|:|.|.|.|:.||.|....:|
Frog   152 GKPEPTITW---------------QQLSEGFSSEGELLEITEINRQQAGDYECVTSNGVSVPDTK 201

  Fly   233 RVSLSVQFAPMV----RAPSQLLGTPLGSDVQLECQVEASPSPVSYWLKG--ARTSNGFASVSTA 291
            :|.::|.:.|.:    .|.|     |:|....|.|:..|.|.....|.|.  .|..:|...:|..
Frog   202 KVQITVNYPPYITDVKNAQS-----PVGRPATLRCKAMAVPPAEFEWYKDEKRRLISGTEGLSIK 261

  Fly   292 SLESGSPGPEMLLDGPKYGITERRDGYRGVMLLVVRSFSPSDVGTYHCVSTNSLGRAEGTLRLYE 356
            :..|.|                         ::|..:.:....|.|.|:::|.||....:|||
Frog   262 TESSWS-------------------------VIVFSNVTSRHYGNYTCLASNKLGSFNSSLRL-- 299

  Fly   357 IKLHPGASASNDDHLN 372
              |.||      |.||
Frog   300 --LKPG------DPLN 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-gamma	NP_651649.1	IG_like	47..139	CDD:214653	23/93 (25%)
		Ig	47..129	CDD:299845	19/83 (23%)
		Ig	140..238	CDD:299845	30/97 (31%)
		IG_like	247..355	CDD:214653	23/109 (21%)
		Ig	256..351	CDD:299845	19/96 (20%)
iglon5	XP_002938252.1	Ig	31..123	CDD:299845	22/95 (23%)
		IG_like	35..123	CDD:214653	22/91 (24%)
		Ig	126..207	CDD:299845	30/97 (31%)
		I-set	128..207	CDD:254352	29/95 (31%)
		I-set	210..299	CDD:254352	24/118 (20%)
		Ig	227..298	CDD:143165	18/95 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	58	1.000	Domainoid score	I10578
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4412
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D265311at33208
OrthoFinder	1	1.000	-	-		FOG0000150
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X97
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970