Protein Alignment CG11828 and PH4alphaNE2

DIOPT Version :10

• Sequence 1: NP_651648.5
• Gene: CG11828 / 43416
• FlyBaseID: FBgn0039616
• Length: 458
• Species: Drosophila melanogaster
• Sequence 2: NP_733378.1
• Gene: PH4alphaNE2 / 43628
• FlyBaseID: FBgn0039783
• Length: 542
• Species: Drosophila melanogaster
• Alignment Length: 525
• Identity: 159/525 - (30%)
• Similarity: 230/525 - (43%)
• Gaps: 106/525 - (20%)

  Fly     1 MASLLQIEDELIGYMRQYAMELQHKVNTMRTFQEEW----MTRRALGPADPTSYVANPLISFPLM 61
            |..:|.:||:|:..:.:.|..|..|..|::     |    |.:|...........|||:.:|.|:
  Fly    37 MDDMLNLEDDLVSNVEKLAEALARKAKTIK-----WGVFKMMKRRQEYKSSMEIFANPIDTFSLI 96

  Fly    62 RR---------TYTDVPKLLELAREE---------FKPGPFQKFIDYDLSSISDVELETAVTGML 108
            |.         .|.:.|    :.:||         ..|..|. |||             |..|:.
  Fly    97 RHMQSNWLMWLLYLETP----VGQEELFFVDSRMPLLPKYFD-FID-------------AAEGIR 143

  Fly   109 RFQGVYGMDESEMANGKLHGKQYNSRMSAADCLAVATHLENVDKGKLACKWFKVAIDQYEEKLDP 173
            :.|..|.|..|::|.|.|.|.||||.:...||||:..||.|..:...|.:|...:|:.|::|...
  Fly   144 KMQATYQMFSSDIAKGLLDGVQYNSSLKPIDCLAIGLHLMNNSRWYAAEQWISASIEAYDQKSSQ 208

  Fly   174 VNRLLQTG--RSQIYEKLGLTLLAMHD----LPASQAAFR---------DSIGWASKEDNT--DL 221
            .:..|..|  .:.:...||...:...:    |.|.|.|.:         :......|.|.|  |:
  Fly   209 TDMELLRGPKLADLCRILGQVQMKQRNHEGALQAYQVALKLSPHDPEIYEEYRILEKRDLTLSDI 273

  Fly   222 AKHLKDKLAHMFVHVDN----------CRGKNLLP-SKSYLRCRYLRDGSPFLRMAPVKLEQLNI 275
            ....:||        ||          |.|:..:| :.|.|.|.|....||||::||:|.|.|:|
  Fly   274 EPIEQDK--------DNSHERLVLPPCCSGRCQVPRNLSNLYCVYNHVTSPFLQLAPIKTEILSI 330

  Fly   276 EPFVGLFHDAISPAEQKDLLHLTDSRLEH------RKKDSSSVEAKVDT-----------NASDH 323
            :|||.|.||.||   ||:...:..|..||      ...|:|..|.:|||           :.:|.
  Fly   331 DPFVVLLHDMIS---QKESTLIRTSSKEHMLPSATTDPDASDDETQVDTYRTSKSVWYSSDFNDT 392

  Fly   324 VRRIHQRIEDITGFDLEESEPLTVSNYGIGGQDFIHLD--CEQPKEFIGYYPKEYRSASAMFYLS 386
            .::|.:|:.|.||.|:..:|...|.|||:||....|||  ..:...|.|   ...|.|:.:|||:
  Fly   393 TKKITERLGDATGLDMNSTEFYQVINYGLGGFFETHLDMLLSEKNRFNG---TSDRIATTLFYLN 454

  Fly   387 DVQMGGYASFPDLGFGFKPRRGSALVWHNTDNSGNCDTRSLQATCPVLLGNQWVAKKWISGSGQW 451
            :|:.||...||.|.....|:.||||.|:|.|..||....||...|||::|::||..|||:..||.
  Fly   455 EVRQGGGTYFPRLNLTVFPQPGSALFWYNLDTKGNDHMGSLHTGCPVIVGSKWVMSKWINDMGQE 519

  Fly   452 RRKSC 456
            ..:.|
  Fly   520 FTRPC 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11828	NP_651648.5	P4Ha_N	1..128	CDD:462433	36/148 (24%)
		P4Hc	287..445	CDD:214780	61/176 (35%)
PH4alphaNE2	NP_733378.1	P4Ha_N	33..163	CDD:462433	36/148 (24%)
		TPR repeat	175..200	CDD:276809	8/24 (33%)
		TPR_16	176..254	CDD:433202	18/77 (23%)
		NrfG	217..>260	CDD:443378	6/42 (14%)
		TPR repeat	219..249	CDD:276809	6/29 (21%)
		P4Hc	342..513	CDD:214780	61/176 (35%)