DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11828 and CG34041

DIOPT Version :9

Sequence 1:	NP_651648.5	Gene:	CG11828 / 43416	FlyBaseID:	FBgn0039616	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_001034077.5	Gene:	CG34041 / 3885583	FlyBaseID:	FBgn0054041	Length:	568	Species:	Drosophila melanogaster

Alignment Length:	325	Identity:	69/325 - (21%)
Similarity:	132/325 - (40%)	Gaps:	65/325 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SLLQIEDELIGYMRQYAMELQHKVNTMRTFQEEWMTRRALGPADPTSYVANPLISFPLMRRTYTD 67
            ::|:|::.::.|:..|...|:.|:.|:.....:..|.......|..:..::|:.|:.|:....:|
  Fly   266 NILKIQENVVKYLENYIYALETKLKTIDEALIDLATYHIQFERDKLAIASSPVASYSLIHHMQSD 330

  Fly    68 VPKLLELAREEFKPGPFQKFIDYDLSSISDV--------ELETAVTGMLRFQGVYGMDESEMANG 124
            ........:|:  ||      ..:|:|:..:        ::.....|:.:....|.|...::|||
  Fly   331 WTHWQLFLQED--PG------KDELASLMSIKKYLPTKNDISEVCHGISKMLNAYLMTAQDIANG 387

  Fly   125 KLHGKQ--YNSR-----------------MSAADCLAVATH---LENVDKGKLACKWFKVAIDQY 167
            .:.|.|  |.|.                 ||..||:|::.|   :::.:|.|   :|..|||...
  Fly   388 VILGTQTKYISSALKLEYLYMEIICNRHLMSLRDCVALSDHSMEMKDYNKSK---EWLNVAISML 449

  Fly   168 EEKL--DPV--NRLLQTGRSQIYEKLGLTLLAMHDLPASQAAFRDSIGWASKED--NTDLAKHLK 226
            |...  ||:  :..|....:::|.|.....||:           :::.:|.|.:  |..|.:..|
  Fly   450 ESSAYWDPIVPSADLYLKLAEVYVKQQNWTLAL-----------ETVEFALKSNPRNAQLIRMQK 503

  Fly   227 DKLAHMFVHVDNCRGKNL------LPSKSYLRCRY-LRDGSPFLRMAPVKLEQLNIEPFVGLFHD 284
            ....|:.:........|:      |.....|.|.| .:..:.:..:||:|.|.|.|:|.|.|:|:
  Fly   504 RLSYHILLGPPKSPKLNIENNDYRLRKNGSLYCFYDTKIRTFYSLLAPIKAEVLFIDPLVILYHE 568

Fly 285 284
Fly 569 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11828	NP_651648.5	P4Ha_N	1..126	CDD:285528	24/130 (18%)
CG11828	NP_651648.5	P4Hc	287..445	CDD:214780
CG34041	NP_001034077.5	P4Ha_N	29..138	CDD:285528
		P4Ha_N	260..389	CDD:285528	24/130 (18%)
		TPR repeat	452..491	CDD:276809	8/49 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461997
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840