DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11828 and PH4alphaNE3

DIOPT Version :9

Sequence 1:	NP_651648.5	Gene:	CG11828 / 43416	FlyBaseID:	FBgn0039616	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_651814.1	Gene:	PH4alphaNE3 / 326114	FlyBaseID:	FBgn0051017	Length:	481	Species:	Drosophila melanogaster

Alignment Length:	490	Identity:	139/490 - (28%)
Similarity:	214/490 - (43%)	Gaps:	87/490 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LLQIEDELIGYMRQYAMELQHKVNTMRTFQEEWMTRRALGPAD--PTSYVANPLISFPLMRRTYT 66
            |:|::.|||..:..||.::..|.:.::...:|  .|:.|..|.  ...|:.|||.||||:|..|.
  Fly    27 LMQLDVELIDNLMNYAEKIDEKASQLKRLAQE--LRQPLHSAKGREEEYLGNPLHSFPLIRHMYQ 89

  Fly    67 DVPKLLELAREEFKPGPFQ----KFIDYDLSSIS-DVELETAVTGMLRFQGVYGMDESEMANGKL 126
            |...|     |||...|..    :|:...|..:. .|:.|.|...:.|....|||...:||||.:
  Fly    90 DWRYL-----EEFMKKPVGEEEIQFLRRKLPELPWQVDTEEASVSIFRIAETYGMMPWDMANGLI 149

  Fly   127 HGKQYNSRMSAADCLAVATHLENVDKGKLACKWFKVAIDQYEEKLDPVNRLLQTGRSQIYEKLGL 191
            ...::||.:.|.||..||.........|.|.:|..::..:.:|:.           |.:||.||:
  Fly   150 DNVRFNSTLPALDCFEVAKMYFKWGYFKQALQWITISKARMKEEY-----------SGVYEVLGM 203

  Fly   192 TLLAMHDLPASQAAF------RDSIGWASKE---DNTDLAKH---LKDKL-AHMFVHVDN----- 238
            .   ..|:...||..      ||.    :.|   |..|||.:   |.|:. |:.:..:|:
  Fly   204 N---RQDVALLQARCLVELDRRDE----AHEVLLDQPDLADNSISLLDQFKANPYEAIDSSPKLG 261

  Fly   239 ------CRGKNLLPSKSYLRCRYLRDGSPFLRMAPVKLEQLNIEPFVGLFHDAISPAEQKDLLHL 297
                  || .:..|:.|.|.|||....|.||.:||:|:|::::||.:.::||.:...:.:.|:.|
  Fly   262 EGYKRLCR-SSFSPNPSKLHCRYNSTTSAFLILAPLKMEEISLEPHIVVYHDILPDKDIQQLITL 325

  Fly   298 TDSRL-------EHRKKDSSSVEAKVDTNASDHVRRIHQRIEDITGFDLEESEPLTVSNYGIGG- 354
            .:..|       :::.:..||....:.....|   .:.||:.||||..:.:..|:.:..||.|.
  Fly   326 AEPLLKPTEMFDDNKNEARSSYRTPLGGPLLD---SLTQRMRDITGLQIRQGNPINIIKYGFGAP 387

  Fly   355 ----QDFIHLDCEQPKEFIGYYPKEYRSASAMFYLSDVQMGGYASFPDLGFGFKPRRGSALVWHN 415
                .||......:.|.|      ..|.|:.||||:|...||...||.|.......||..|.|:|
  Fly   388 YTNYYDFFKKRNSESKGF------GDRMATFMFYLNDAPYGGATVFPRLNVKVPAERGKVLFWYN 446

  Fly   416 TDNSGNCDTRSLQ-----ATCPVLLGNQWVAKKWI 445
            .    |.||..::     |.|||..|::||...||
  Fly   447 L----NGDTHDMEPTTMHAACPVFHGSKWVMTAWI 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11828	NP_651648.5	P4Ha_N	1..126	CDD:285528	41/128 (32%)
CG11828	NP_651648.5	P4Hc	287..445	CDD:214780	47/174 (27%)
PH4alphaNE3	NP_651814.1	P4Ha_N	25..149	CDD:285528	41/128 (32%)
PH4alphaNE3	NP_651814.1	P4Hc	316..478	CDD:214780	49/175 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461847
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	9	8.900