DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11828 and CG31016

DIOPT Version :9

Sequence 1:	NP_651648.5	Gene:	CG11828 / 43416	FlyBaseID:	FBgn0039616	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_001263119.1	Gene:	CG31016 / 326113	FlyBaseID:	FBgn0051016	Length:	536	Species:	Drosophila melanogaster

Alignment Length:	482	Identity:	132/482 - (27%)
Similarity:	221/482 - (45%)	Gaps:	51/482 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LLQIEDELIGYMRQYAMELQHKVNTMRTFQEEWMTRRALGPADPTSYVANPLISFPLMRRTYTD- 67
            ||:.:.|||..:..||.||..|:..::...:|:.............|::||:.|..|||:.:.|
  Fly    38 LLEKDRELIIVLDSYATELNEKIIMLKRIVKEFKQPLEKAKNREEEYLSNPIDSLSLMRQMHEDW 102

  Fly    68 --VPKLLELAREEFKPGPFQKFIDYDLSSISDVELETAVTGMLRFQGVYGMDESEMANGKLHGKQ 130
              |.|||:....:.|....:|..: ||...:|  |..|...|.|....|.::..:::.|.:.|.|
  Fly   103 EKVEKLLKKPVGQEKIALVEKMRE-DLPVEND--LMEANQAMFRILHTYDLEPKDVSAGWIDGVQ 164

  Fly   131 YNSRMSAADCLAVATHLENVDKGKLACKWFKVAIDQYEEKLDPVNRLLQTGRSQIYEKLGLTLLA 195
            |..:|||:||..:.|........::|.||...|.|...::....:.::...::.:...|..:|:|
  Fly   165 YGGKMSASDCFTMGTFSFMAGSYQIASKWLSAAKDLLVDQPRKYHEVMGITKADVTLLLARSLIA 229

  Fly   196 MHDLP-ASQAAFRDSIGWASKEDNTDLAKHLKDKLAHMFVHVDN----------CRG---KNLLP 246
            ..::. |:....||   :...|..:.|..|.........:::::          ||.   :.:..
  Fly   230 SGNVSIATDMLMRD---FMFGEAGSALTVHFLRNKPKPSINLESWESDESFNQLCRSSSRRQMGE 291

  Fly   247 SK-SYLRCRYLRDGSPFLRMAPVKLEQLNIEPFVGLFHDAISPAEQKDLLHLTDSRLEHRK---- 306
            || |.|.|||....:|||::||.::|:|:::|:|..:|:.:|.||.:.|..:....||..|
  Fly   292 SKPSRLHCRYNTITTPFLKLAPFRMEELSLDPYVIFYHNVLSDAEIEKLKPMGKPFLERAKVFRV 356

  Fly   307 -KDSSSVE------------AKVDTNASDHVRRIHQRIEDITGFDLEESEPLTVSNYGIGGQDFI 358
             |.|..::            ..:|.:..:.:.||.:||||:||.:......:....||.||....
  Fly   357 EKGSDEIDPSRSADGAWLPHQNIDPDDLEVLNRIGRRIEDMTGLNTRSGSKMQFLKYGFGGHFVP 421

  Fly   359 HLDCEQPKEF----IGYYPKEYRSASAMFYLSDVQMGGYASFPDLGFGFKPRRGSALVWHNTD-N 418
            |.|....|.|    :|     .|.|:.:|||::|..||...||.|......::||||.|||.| .
  Fly   422 HYDYFNSKTFSLETVG-----DRIATVLFYLNNVDHGGATVFPKLNLAVPTQKGSALFWHNIDRK 481

  Fly   419 SGNCDTRSLQATCPVLLGNQWVAKKWI 445
            |.:.|||:....||::.|.:.|..:||
  Fly   482 SYDYDTRTFHGACPLISGTKLVMTRWI 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11828	NP_651648.5	P4Ha_N	1..126	CDD:285528	34/124 (27%)
CG11828	NP_651648.5	P4Hc	287..445	CDD:214780	54/179 (30%)
CG31016	NP_001263119.1	P4Ha_N	31..160	CDD:285528	34/124 (27%)
CG31016	NP_001263119.1	P4Hc	333..508	CDD:214780	54/179 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461917
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	9	8.900