DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11828 and CG32201

DIOPT Version :9

Sequence 1:	NP_651648.5	Gene:	CG11828 / 43416	FlyBaseID:	FBgn0039616	Length:	458	Species:	Drosophila melanogaster
Sequence 2:	NP_730346.2	Gene:	CG32201 / 317911	FlyBaseID:	FBgn0052201	Length:	520	Species:	Drosophila melanogaster

Alignment Length:	482	Identity:	134/482 - (27%)
Similarity:	230/482 - (47%)	Gaps:	51/482 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MASLLQIEDELIGYMRQYAMELQHKVNTMRTFQEE--WMTRRALGPADPTSYVANPLISFPLMRR 63
            :..||::|::....:.....:|..|...:|.:...  :...|:|.  :...||:||:.:|.|:||
  Fly    40 LLKLLKVEEKFTDNLLNQVDQLGEKFEALRMYLSSVGYELHRSLN--EKVQYVSNPINAFSLLRR 102

  Fly    64 TYTDVPKLLELAREEFKPGPFQKFIDYDLSSISDVELETAVTGMLRFQGVYGMDESEMANGKLHG 128
            |:.|:||..|..:|....|.....:|......:||::.:|:.|:.|.:.:|.:...::|.|.|.|
  Fly   103 THEDLPKWHEYFKEAIGEGNQSILVDLVKMVPNDVDMLSAMHGIQRIEKIYDLKIDDLAQGVLQG 167

  Fly   129 KQYNSRMSAADCLAVATHLENVDKGKLACKWFKVAID---QYEEKL------DPVNRLLQTGRSQ 184
            .|||.:::..|.:|:...:......:.|.||:::|..   :..|:|      ||...|.:.....
  Fly   168 VQYNVQLTYRDLIAMGNSMYQQSDYQTAAKWYRIACKRELENPEQLFIQILGDPSEHLHRQYIKS 232

  Fly   185 IYEKLGLTLLAMHDLPASQAAFRDSIGWASKEDNTDLAKHLKDKLAHMFVHVD------------ 237
            :: |.|.|  ......:.:.||  .:..||:|:..::...|.:....:.|..|
  Fly   233 LF-KYGST--TSEPSKSIEEAF--IMVQASQEELDNIMSDLNEPQNDVEVEKDLYQVKRSPSNCE 292

  Fly   238 -NCRGKNLLPSKSYLRCRYLRDGSPFLRMAPVKLEQLNIEPFVGLFHDAISPAEQKDLLHLTDSR 301
             .|||  |...|:.|.|||....:.|||:||:|||:::::||:.::|:.:..:|.::|...:.:.
  Fly   293 LGCRG--LYRQKTNLVCRYKSTANTFLRLAPLKLEEISLDPFMAMYHEVLYDSEIRELKGQSMNM 355

  Fly   302 LEHRKKDSSSVEAKVDT--------NASDHVRRIHQRIEDITGFDLEESEPLTVSNYGIGGQDFI 358
            :.......:..|.: ||        |.|....||:|||.|:|||:..:.|.|.::|||:|.....
  Fly   356 VNGYASQRNGTEIR-DTVVRYDWWSNTSLVRERINQRIIDMTGFNFLKDEKLQIANYGLGTYFQP 419

  Fly   359 HLDCEQPKEFIGYYPKEY-----RSASAMFYLSDVQMGGYASFPDLGFGFKPRRGSALVWHNTDN 418
            |.|....    |:.....     |.||.:||.|:|..||...||::.....|::||.|.|.|..:
  Fly   420 HFDYSSD----GFETPNITTLGDRLASILFYASEVPQGGATVFPEINVTVFPQKGSMLYWFNLHD 480

  Fly   419 SGNCDTRSLQATCPVLLGNQWVAKKWI 445
            .|..|.|||.:.||||.|::|...||:
  Fly   481 DGKPDIRSLHSVCPVLNGDRWTLTKWV 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11828	NP_651648.5	P4Ha_N	1..126	CDD:285528	32/126 (25%)
CG11828	NP_651648.5	P4Hc	287..445	CDD:214780	54/170 (32%)
CG32201	NP_730346.2	P4Ha_N	36..165	CDD:285528	32/126 (25%)
CG32201	NP_730346.2	P4Hc	341..507	CDD:214780	54/170 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461838
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	1	1.000	-	-		mtm1209
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10869
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
	9	8.900