Protein Alignment CG11828 and P4HA3

DIOPT Version :9

• Sequence 1: NP_651648.5
• Gene: CG11828 / 43416
• FlyBaseID: FBgn0039616
• Length: 458
• Species: Drosophila melanogaster
• Sequence 2: NP_001275677.1
• Gene: P4HA3 / 283208
• HGNCID: 30135
• Length: 604
• Species: Homo sapiens
• Alignment Length: 497
• Identity: 112/497 - (22%)
• Similarity: 186/497 - (37%)
• Gaps: 156/497 - (31%)

  Fly     1 MASLLQIEDELIGYMRQYAMELQHKVNTMRTFQEEWMTRRALGPADPTSYVANPLISFPLMRRTY 65
            :|..|..|..|:|.:|:|....:.::..:..|.::.::..    .|.|:.|||||::|.|::|..
Human    37 VARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKVLSLH----EDSTTPVANPLLAFTLIKRLQ 97

  Fly    66 TD---VPKLLELAR--EEFKPGPFQKFIDYDLSSISDVELETAVTGMLRFQGVYGMDESEMANG- 124
            :|   |...||.:.  ...|.| ::| ::.||.:..|  ||.|...::|.|.||.::...:|.|
Human    98 SDWRNVVHSLEASENIRALKDG-YEK-VEQDLPAFED--LEGAARALMRLQDVYMLNVKGLARGV 158

  Fly   125 ----------KLHGKQYNSRMSAADCLAVATHLENVDKGKLACKWFKVAIDQYEEKLDPVNRLLQ 179
                      .|:..:....::..||..|.                |||.|.
Human   159 FQRVTGSAITDLYSPKRLFSLTGDDCFQVG----------------KVAYDM------------- 194

  Fly   180 TGRSQIYEKLGLTLLAMHDLPASQAA---FRDSIGWASKEDNTDLAKHLKDKLAHMFVHV----- 236
               ...|          |.:|..:.|   ||.|.|....||...|...| |.||..:...
Human   195 ---GDYY----------HAIPWLEEAVSLFRGSYGEWKTEDEASLEDAL-DHLAFAYFRAGNVSC 245

  Fly   237 -------------DNCR-GKNLL---------------------PSKSYLR-------------- 252
                         ||.| .:|:|                     |:..:|:
Human   246 ALSLSREFLLYSPDNKRMARNVLKYERLLAESPNHVVAEAVIQRPNIPHLQTRDTYEGLCQTLGS 310

  Fly   253 -----------CRYLRDGSPFLRMAPVKLEQLNIEPFVGLFHDAISPAEQKDLLHLTDS------ 300
                       |.|..:.:.:|.:.|::.|.:::||::.|:||.:|.:|.:.:..|.:.
Human   311 QPTLYQIPSLYCSYETNSNAYLLLQPIRKEVIHLEPYIALYHDFVSDSEAQKIRELAEPWLQRSV 375

  Fly   301 --------RLEHRKKDSSSVEAKVDTNASDHVRRIHQRIEDITGFDLEE--SEPLTVSNYGIGGQ 355
                    ::|:|...|:.::..||..    :..::.||..:||.|:..  :|.|.|.||||||.
Human   376 VASGEKQLQVEYRISKSAWLKDTVDPK----LVTLNHRIAALTGLDVRPPYAEYLQVVNYGIGGH 436

  Fly   356 DFIHLD-CEQPKEFIGYYPKEYRSASAMFYLSDVQMGGYASF 396
            ...|.| ...|...:.......|.|:.|.|||.|:.||..:|
Human   437 YEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVEAGGATAF 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11828	NP_651648.5	P4Ha_N	1..126	CDD:285528	37/140 (26%)
		P4Hc	287..445	CDD:214780	35/127 (28%)
P4HA3	NP_001275677.1	P4Ha_N	58..159	CDD:285528	30/108 (28%)
		TPR_12	186..252	CDD:290160	20/108 (19%)
		P4Hc	356..>478	CDD:214780	34/125 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165149293
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1591
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D192165at33208
OrthoFinder	1	1.000	-	-		FOG0000199
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X129
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.750