DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Doa and AT3G25840

DIOPT Version :9

Sequence 1:	NP_001014681.2	Gene:	Doa / 43415	FlyBaseID:	FBgn0265998	Length:	2045	Species:	Drosophila melanogaster
Sequence 2:	NP_189213.2	Gene:	AT3G25840 / 822178	AraportID:	AT3G25840	Length:	935	Species:	Arabidopsis thaliana

Alignment Length:	1021	Identity:	201/1021 - (19%)
Similarity:	390/1021 - (38%)	Gaps:	204/1021 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1089 SSSSCVPSPRCAAAFFRRPQEANNPQQQHHQPLQKPQQV---------------API-------- 1130
            ||||...:.:.:.....|..:.::.:.:||:..::..::               |||
plant    17 SSSSSDDTEKASKRHKHRHHKHHHHRHRHHRDKKRENEIPSAGDETEILDVTPAAPIVVSNGCEE 81

  Fly  1131 ---------EESGPGDSASLERKSEKSNSTLSTSSFTVTNCCTTHLPQLSKFTSSFHIAPTTATT 1186
                     ||.|.||   :..|:..|:.......|...|     ||.|.:             .
plant    82 EDVEEGEILEEDGIGD---VLMKTADSDGESGEIKFEDNN-----LPPLGE-------------K 125

  Fly  1187 TAATATPTPTGAATTSDQQQ-----QSGGTPAMVAANLEVPTSSSSSAATKRQKDVDNKLEKCLN 1246
            .......:..|..|...:::     :..|.|:...:.|......||.:.:..::..:.:...
plant   126 GRQGEEKSSNGVLTRESEREDKRWDKEAGGPSERVSKLSYDNGRSSFSPSNSRQSNEGRARS--- 187

  Fly  1247 DMLKLKTSSNNNSTSNSNNNAIMSHSLTGEHKDPKTALEGPTSSSSSSSSKYIGESQIPVPVQLY 1311
               :.|:......||.| ..|....|..|.|.|...........|..:..:|....:.....:.|
plant   188 ---RSKSHDRERETSRS-RFAEDEFSDRGRHHDSSRDYHHDRVDSVRTEERYHRRGRYEENDRQY 248

  Fly  1312 DPQKPLLQQQQQQQRICYPIGKSNSTSQLPMGGYQRLLQHQQQQHHQQQQQQHQEQQQYPQHKRP 1376
              .:.:|::.:.::|   .:.:..|.......|.:|..:...::..::::::.:.:....:.|.
plant   249 --SREVLERDRSKER---DMDREGSIRDRDSEGSKRRDKDSDRRREREREKRREIESDRERRKE- 307

  Fly  1377 FLNWNSFACSAMNGASDPFMQQQHMPAHQQQQHLPHKLQQSYSSSHVPKQAPKSGLAMFLQKNTN 1441
                                       .::::.:....::.....::..:|.:.|.:....:..:
plant   308 ---------------------------KERERSIDRDRRKEREGDYLRDRANERGRSRDRTRYNS 345

  Fly  1442 KENKFGQPMQQQPPGMMPQMYGYQAPQQQSK-----IGYPRTGAPLTHSASFSS---------AQ 1492
            :|.|    .:::..|......|.:..:.:.|     :.|    ..:.|..|.::         .:
plant   346 RERK----REKEREGEKDWERGRETQKDREKYISSDVDY----GEMRHKQSRNTRYDAVDDLEMR 402

  Fly  1493 RPTALQFHQQHQQQQHLQQQQQHPQQQQHQ----HSSFGVGMMS-----RNYYNMPKQPERKPLQ 1548
            :|.:|:.|  :.:...|::...:.::.:::    .:..|:...|     ....|..|:..||.::
plant   403 KPNSLKAH--NSKGDKLEETWANDERSRNEDGQDDNDEGLTWKSPEEEEEELLNRIKEESRKRME 465

  Fly  1549 TFDPYAYPKPNQMQPVKYQQQQQH--PHTQFQNAS------AGGGGGGAAGLQYDP-NTNTQLFY 1604
            ........||.|...:..|...:.  |.|....::      |...|.....|.:|. .....|..
plant   466 AILEKHKRKPEQQNELLTQDNGKDIVPETGAPVSTSPAVVIAANVGQAKTNLDFDTVAAKAPLIA 530

  Fly  1605 ASPASSSSNKQPQQPQQQQQQQQSQLQQSNSVIFNHSGQQHQPHQQQQNEMSKSALGLHFI---E 1666
            ..|.:.|.....::.|.|....:...:...|....|           .:...:|..|:..:   .
plant   531 GGPPTMSGISDSEKNQAQAGLGEGSPKSERSADMFH-----------DDIFGESPAGIRKVGGKG 584

  Fly  1667 TAKPVIQ-------DDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMERDYC----MAL 1720
            ...|:::       |||:|:..|..|::|..||:::||.|:|.|..||:.||::....    :|:
plant   585 DGVPMVRSGLHDNWDDAEGYYSYQFGELLDGRYEVIATHGKGVFSTVVRAKDLKAGPAEPEEVAI 649

  Fly  1721 KIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRE- 1784
            |||:|.|...:|.|:|:..|:|:|..|......||:.:..|.|..|:|:|||.|.|::.:.|::
plant   650 KIIRNNETMHKAGKIEVQILKKLAGADREDRRHCVRFLSSFKYRNHLCLVFESLHLNLREVLKKF 714

  Fly  1785 NNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNT 1849
            .......|..||..:.||..::|.|.:..:.|.|:||:|:|                 |...||.
plant   715 GRNIGLQLSAVRAYSKQLFIALKHLKNCGVLHCDIKPDNML-----------------VNEGKNV 762

  Fly  1850 DVRLIDFGSATFDHEHHST--IVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTH 1912
             ::|.|||:|.|..::..|  :|| |.||:||:||.|.:..|.|:||:||.|:|||.|..||...
plant   763 -LKLCDFGNAMFAGKNEVTPYLVS-RFYRSPEIILGLTYDHPLDIWSVGCCLYELYSGKVLFPGA 825

  Fly  1913 DNREHLAMMERILGQIPYRMARNHTLYSKTKTKYFYHGKLDW---DEKSSAGRYVRD---HCKPL 1971
            .|.:.|.:...:.|..|.:|.|......    ::|.| .|::   :|.:.:|:.::.   :.||.
plant   826 TNNDMLRLHMELKGPFPKKMLRKGAFID----QHFDH-DLNFYATEEDTVSGKLIKRMIVNVKPK 885

  Fly  1972 FLCQL------SDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPF 2011
            ....:      .|.:.......|:.||...:|..|:|:.:||.|||
plant   886 DFGSIIKGYPGEDPKILAHFRDLLDKMFILDPERRLTVSQALAHPF 931

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Doa	NP_001014681.2	PKc_CLK	1679..2012	CDD:271036	110/352 (31%)
Doa	NP_001014681.2	S_TKc	1692..2012	CDD:214567	106/339 (31%)
AT3G25840	NP_189213.2	PRP38_assoc	186..266	CDD:289628	14/91 (15%)
		DUF1777	315..>439	CDD:285811	14/133 (11%)
		STKc_PRP4	616..932	CDD:271037	107/340 (31%)
		S_TKc	617..932	CDD:214567	106/339 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810