Protein Alignment Doa and dyrk1a

DIOPT Version :9

• Sequence 1: NP_001014681.2
• Gene: Doa / 43415
• FlyBaseID: FBgn0265998
• Length: 2045
• Species: Drosophila melanogaster
• Sequence 2: XP_012812685.1
• Gene: dyrk1a / 779733
• XenbaseID: XB-GENE-1017105
• Length: 771
• Species: Xenopus tropicalis
• Alignment Length: 596
• Identity: 147/596 - (24%)
• Similarity: 248/596 - (41%)
• Gaps: 140/596 - (23%)

  Fly  1482 LTHSASFSSAQRPTALQFHQQHQQQQHLQQQQQHPQQQQHQHSSFGVGMMSRNYYNMPKQP---E 1543
            |..|.||.:|....|.|....|||....:||..:.||..           :..|.:..:||   :
 Frog    37 LAPSFSFHAAGLQMAGQMSHSHQQYSDRRQQNLNDQQAS-----------ALPYNDQIQQPLPNQ 90

  Fly  1544 RKPLQTF-DPYAYPKPNQMQPVKYQQQQQHPHTQFQNASAGGGGGGAAGLQYDPNTNTQLFYASP 1607
            |:..||| ||...|    ::.:.....:.:.|.                        .:::||
 Frog    91 RRMPQTFRDPATAP----LRKLSVDLIKTYKHI------------------------NEVYYA-- 125

  Fly  1608 ASSSSNKQPQQPQQQQQQQQSQLQQSNSVIFNHSGQQHQPHQQQQNEMSKSALGLHFIETAKPVI 1672
                        :::::.||.|...|:          |:..::..|:.
 Frog   126 ------------KKKRRHQQGQGDDSS----------HKKERKVYNDG----------------- 151

  Fly  1673 QDDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMERDYCMALKIIKNVEKYREAAKLEI 1737
            .||.:...|...|:....||:|.:.:|:|:||:|||..|......:|:|||||.:.:...|::|:
 Frog   152 YDDDNYDYIVKNGEKWMDRYEIDSLIGKGSFGQVVKAYDRAEQEWVAIKIIKNKKAFLNQAQIEV 216

  Fly  1738 NALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQL 1802
            ..||.:.:.|....:..|.:...|.:..|:|:|||||..:::|.||..|:....|:..|..|.|:
 Frog   217 RLLELMNKHDTEMKYYIVHLKRHFMFRNHLCLVFEMLSYNLYDLLRNTNFRGVSLNLTRKFAQQM 281

  Fly  1803 CYSVKFLHDNRLT--HTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEH 1865
            |.::.||....|:  |.||||||||..:.                 |.:.::::||||:....:.
 Frog   282 CTALLFLATPELSIIHCDLKPENILLCNP-----------------KRSAIKIVDFGSSCQLGQR 329

  Fly  1866 HSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPY 1930
            ....:.:|.||:|||:|.:.:....|:||:||||.|::.|..||...:..:.::.:..:||..|
 Frog   330 IYQYIQSRFYRSPEVLLGMPYDLAIDMWSLGCILVEMHTGEPLFSGANEVDQMSKIVEVLGIPP- 393

  Fly  1931 RMARNHTLYSKTKTKYFYHGKLD--WD-EKSSAGRYVRDHCKPLFLCQLSD-------------- 1978
                .|.|....|.:.|:....:  |: :|:..|   :...||....:|.:
 Frog   394 ----AHILDQAPKARKFFEKMPEGTWNLKKTKDG---KKEYKPPGTRKLHNLLGVETGGPGGRRG 451

  Fly  1979 ------SEDHCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPH--HRVGEVSN----KQPLS 2031
                  ..|:.:...||.:||:|:..:||....||.|.||.:....  :....||.    :|..|
 Frog   452 GESGHTVADYLKFKDLILRMLDYDAKTRIQPYYALQHSFFKKTADEGTNTSNSVSTSPAMEQSQS 516

  Fly  2032 SGSSSRERSHS 2042
            ||::|...|.|
 Frog   517 SGTTSSTSSSS 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doa	NP_001014681.2	PKc_CLK	1679..2012	CDD:271036	101/357 (28%)
		S_TKc	1692..2012	CDD:214567	98/344 (28%)
dyrk1a	XP_012812685.1	PKc_DYRK1	160..496	CDD:271128	103/360 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910