DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Doa and clk3

DIOPT Version :9

Sequence 1:	NP_001014681.2	Gene:	Doa / 43415	FlyBaseID:	FBgn0265998	Length:	2045	Species:	Drosophila melanogaster
Sequence 2:	NP_001011462.1	Gene:	clk3 / 496952	XenbaseID:	XB-GENE-5861130	Length:	498	Species:	Xenopus tropicalis

Alignment Length:	416	Identity:	219/416 - (52%)
Similarity:	288/416 - (69%)	Gaps:	22/416 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly  1606 SPASSSSNKQPQQPQQQQQQQQSQLQQSNSVIFNH---SGQQHQPHQQQQNEMSKSALGLHFIET 1667
            |.:.|.|.:.|.:|..:.:.:....:|.:.:...|   ||.......|:..:.|::
Frog    86 SKSYSYSTRSPARPHSRDRTKTKAEKQPHKISHKHSTRSGSYSSSKSQRSTKDSQN--------- 141

  Fly  1668 AKPVIQDDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKDMER-DYCMALKIIKNVEKYRE 1731
                :::|.:|||:..||:.:..||:|:..||:||||:||:..|:.| :..:|||||:||.||||
Frog   142 ----VENDKEGHLVCRTGERIQERYEIVGDLGKGTFGKVVECLDLARGNSRVALKIIRNVRKYRE 202

  Fly  1732 AAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVR 1796
            ||:||||.||||.::|....::||.|.||||:|||:||.||:||.|.|:|.:|||:.||||..:|
Frog   203 AAQLEINVLEKIKERDQDNKNMCVLMRDWFDFHGHVCIAFELLGKSTFEFQKENNFLPYPLAHIR 267

  Fly  1797 HMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATF 1861
            |||:|||.::||||:|:||||||||||||||:|:|...||.....|.:.|||..:|::|||||||
Frog   268 HMAFQLCQALKFLHENQLTHTDLKPENILFVNSEYDICYNESKKCEEKCVKNPSIRIVDFGSATF 332

  Fly  1862 DHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILG 1926
            |||:|:|||:|||||.|||||||||||||||||:||||||.|.|.||||||||||||.|||:|||
Frog   333 DHEYHTTIVATRHYRPPEVILELGWSQPCDVWSLGCILFEYYTGFTLFQTHDNREHLVMMEKILG 397

  Fly  1927 QIPYRMARNHTLYSKTKTKYFYHGKLDWDEKSSAGRYVRDHCKPLFLCQLSDSEDHCELFSLIKK 1991
            .:|.||     :|...|.|||::|.|.|||.||.||||..:|..|...:.|||.:|.:||.|:.:
Frog   398 PLPRRM-----VYKTRKQKYFHNGSLIWDENSSDGRYVSKNCHQLMSYKSSDSAEHVQLFDLLSR 457

  Fly  1992 MLEYEPSSRITLGEALHHPFFDRLPP 2017
            |||:.|:.||||.|||.|.||..|.|
Frog   458 MLEFRPALRITLQEALEHQFFTCLKP 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Doa	NP_001014681.2	PKc_CLK	1679..2012	CDD:271036	202/333 (61%)
Doa	NP_001014681.2	S_TKc	1692..2012	CDD:214567	197/320 (62%)
clk3	NP_001011462.1	PKc_like	148..478	CDD:389743	203/334 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000672
OrthoInspector	1	1.000	-	-		otm47924
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X440
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910