Protein Alignment Doa and pom1

DIOPT Version :9

• Sequence 1: NP_001014681.2
• Gene: Doa / 43415
• FlyBaseID: FBgn0265998
• Length: 2045
• Species: Drosophila melanogaster
• Sequence 2: NP_592974.1
• Gene: pom1 / 2541889
• PomBaseID: SPAC2F7.03c
• Length: 1087
• Species: Schizosaccharomyces pombe
• Alignment Length: 1284
• Identity: 277/1284 - (21%)
• Similarity: 473/1284 - (36%)
• Gaps: 356/1284 - (27%)

  Fly   786 AISSGLSKSSSINFAQNPSSR------GAAPRLAYPSIFSQAAGE------PKLQRSISSSNMPI 838
            |:|.|...:.:: |..:.|:|      |....|..||..| |.|.      |..|.|.|:
pombe     9 AVSLGDENTDAL-FKLHTSNRKSANMFGIKSELLNPSELS-AVGSYSNDICPNRQSSSST----- 66

  Fly   839 SAPNSMRPLPTKNGLQSGSNLSLNKQLMNEFWSENLTSSQKRQTPKRTFWNYE-KICGAQLGDAG 902
            :|..|    |:.|.  |.:|:|..:|                :.....|.|.| |..|:.:.:
pombe    67 AADTS----PSTNA--SNTNISFPEQ----------------EHKDELFMNVEPKGVGSSMDN-- 107

  Fly   903 QPFKVDAKTAKKL--AIFDPTVAEAAQKELQRPQQSQVPQNQPHKLQKNASLSHLDLKVRQAVTK 965
            ....:...|...|  :.||...           :|...|:|..|:| .|.|:
pombe   108 HAITIHHSTGNGLLRSSFDHDY-----------RQKNSPRNSIHRL-SNISI------------- 147

  Fly   966 DDLYKLICNEQSPLAGSNFVSRVPVKQQFPAQQQQVLPKSM--SMTHVPGGGQPMGAPLLRTSSR 1028
                           |:|     |:  .|.:.||. .|.|:  |..|             ||||.
pombe   148 ---------------GNN-----PI--DFESSQQN-NPSSLNTSSHH-------------RTSSI 176

  Fly  1029 THIPSYMKNLPSLSRSTSNS-------------AILMTQPRKEPPPKEPLKAPAPLPAIAAPTVG 1080
            ::..|:..:|...:||:..|             .|.:||.....|.:..:.:... .|..|....
pombe   177 SNSKSFGTSLSYYNRSSKPSDWNQQNNGGHLSGVISITQDVSSVPLQSSVFSSGN-HAYHASMAP 240

  Fly  1081 KPSGVLKSSSSSCVPSPRCAAAFFRRPQEANNPQQQHHQPLQKPQQVAPIEESGPGDSASLERKS 1145
            |.||..:.::......||.|:                   :.....:.|:....|....|.:.:.
pombe   241 KRSGSWRHTNFHSTSHPRAAS-------------------IGNKSGIPPVPTIPPNIGHSTDHQH 286

  Fly  1146 EKSN--STLSTSSFTVTNCCTTHLPQLSKFTSSF--HIAP-TTATTTAATATPTPTGAATTSDQQ 1205
            .|:|  .:|:.||....|..|...|  .|.::||  .::| :..|.:......:..|:.|.|
pombe   287 PKANISGSLTKSSSESKNLSTIQSP--LKTSNSFFKELSPHSQITLSNVKNNHSHVGSQTKS--- 346

  Fly  1206 QQSGGTPAMVAANLEVPTSSSSSAATKRQ--KDVDNKLEKCLNDMLKLKTSSNNNSTSNSNNNAI 1268
             .|..||::...|..|.:.:.::..|..|  .|..|...|.....:..||    |...:.|:.|.
pombe   347 -HSFATPSVFDNNKPVSSDNHNNTTTSSQVHPDSRNPDPKAAPKAVSQKT----NVDGHRNHEAK 406

  Fly  1269 MSHSLTGEHKDPKTALEGPTSSSSSSSSKYIGESQIPVPVQLYDPQKPLLQQQQQQQRICYPIGK 1333
            ..:::..|.|..|::.:...||.....|:                                 :..
pombe   407 HGNTVQNESKSQKSSNKEGRSSRGGFFSR---------------------------------LSF 438

  Fly  1334 SNSTSQLPMGGYQRLLQHQQQQHHQQQQQQHQEQQQYPQHKRPFLNWNSFACSAMNGASDPFMQQ 1398
            |.|:|::..|                .:.:|::....|.....::..:|...|..||...|...:
pombe   439 SRSSSRMKKG----------------SKAKHEDAPDVPAIPHAYIADSSTKSSYRNGKKTPTRTK 487

  Fly  1399 QHMPAHQQQQHL----PHKLQQS--YSSSHVPKQAPKSGLAMFLQKNTNKENKFGQPMQQQPPGM 1457
            ..|     ||.:    |.|.:.|  .|.|..|...|:..:.   :...::|.:..:.:...||
pombe   488 SRM-----QQFINWFKPSKERSSNGNSDSASPPPVPRLSIT---RSQVSREPEKPEEIPSVPP-- 542

  Fly  1458 MPQMY---GYQAPQQQSKIGYPR----TGAPLTHSASFSSAQRPTALQFHQQHQQQQHLQQQQQH 1515
            :|..:   |: .|||:|....|:    |...|..|.||:|:                       :
pombe   543 LPSNFKDKGH-VPQQRSVSYTPKRSSDTSESLQPSLSFASS-----------------------N 583

  Fly  1516 PQQQQHQHSSFGVGMMSRNYYNMPK-QPERKPLQTFDPYAYPKPNQMQPVKYQQQQQHPHTQFQN 1579
            ...:........:.|.:.|...:.| ..:.|.:|:.    ..:...:.||:
pombe   584 VLSEPFDRKVADLAMKAINSKRINKLLDDAKVMQSL----LDRACIITPVR-------------- 630

  Fly  1580 ASAGGGGGGAAGLQYDPNTNTQLFYASPASSSSNKQPQQPQQQQQQQQSQLQQSNSVIFNHSGQQ 1644
                             ||..||...:|.:              :.:|.::...:::.|  :|.:
pombe   631 -----------------NTEVQLINTAPLT--------------EYEQDEINNYDNIYF--TGLR 662

  Fly  1645 HQPHQQQQNEMSKSALGLHFIETAKPVIQDDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKV 1709
            :...::..:|.:.|..|.           ||..|......||.:.:||:::..||:|:||:|::.
pombe   663 NVDKRRSADENTSSNFGF-----------DDERGDYKVVLGDHIAYRYEVVDFLGKGSFGQVLRC 716

  Fly  1710 KDMERDYCMALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEML 1774
            .|.|....:|||||:|.:::...|.:|...|:||.:.||..::..|:..|.|.:..|:|:..|:|
pombe   717 IDYETGKLVALKIIRNKKRFHMQALVETKILQKIREWDPLDEYCMVQYTDHFYFRDHLCVATELL 781

  Fly  1775 GLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKI 1839
            |.::::.::.|.::..|:..::.:..||...:..|::..:.|.||||||||..         |..
pombe   782 GKNLYELIKSNGFKGLPIVVIKSITRQLIQCLTLLNEKHVIHCDLKPENILLC---------HPF 837

  Fly  1840 NREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYL 1904
                    .:.|::|||||:.|:.|...|.:.:|.||:|||||.:|:..|.||||:|||:.|:|.
pombe   838 --------KSQVKVIDFGSSCFEGECVYTYIQSRFYRSPEVILGMGYGTPIDVWSLGCIIAEMYT 894

  Fly  1905 GITLFQTHDNREHLAMMERILGQIPYRMARNHTLYSKTKTKYFYHGKLDWDEK-------SSAGR 1962
            |..||...:.:|.||.:..|.|      ..:|:|..|...|     |:.:|..       ||.|.
pombe   895 GFPLFPGENEQEQLACIMEIFG------PPDHSLIDKCSRK-----KVFFDSSGKPRPFVSSKGV 948

  Fly  1963 YVRDHCKPLFLCQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPF 2011
            ..|...|.|.  |:...:| ....|.|...|:::|..|:|..:|..|.|
pombe   949 SRRPFSKSLH--QVLQCKD-VSFLSFISDCLKWDPDERMTPQQAAQHDF 994

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doa	NP_001014681.2	PKc_CLK	1679..2012	CDD:271036	107/340 (31%)
		S_TKc	1692..2012	CDD:214567	104/327 (32%)
pom1	NP_592974.1	PKc_DYRK	685..995	CDD:271112	108/341 (32%)
		S_TKc	699..995	CDD:214567	104/327 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810