DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Doa and Hipk4

DIOPT Version :9

Sequence 1:NP_001014681.2 Gene:Doa / 43415 FlyBaseID:FBgn0265998 Length:2045 Species:Drosophila melanogaster
Sequence 2:NP_001028487.2 Gene:Hipk4 / 233020 MGIID:2685008 Length:616 Species:Mus musculus


Alignment Length:429 Identity:121/429 - (28%)
Similarity:183/429 - (42%) Gaps:104/429 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly  1692 YKIMATLGEGTFGRVVKVKDMERDYCMALKIIKNVEKYR-EAAKLEINALEKIAQKDPHCDHLCV 1755
            |.|:..||:||||.|.|.........:|:||:|| :.|| ...|.|:..|..:...||...|: :
Mouse    11 YDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKN-DAYRSRIIKNELKLLRCVRGLDPDEAHV-I 73

  Fly  1756 KMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLK 1820
            :.:::|.......:|||:|..::|:|.:|||:.|.|...:|.:..|:..::..|.:..:.|.|||
Mouse    74 RFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQVLRALARLKELAIIHADLK 138

  Fly  1821 PENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHH---STIVSTRHYRAPEVIL 1882
            ||||:.||.          .|...|||     :||||||:...|..   ...:.:|.|||||::|
Mouse   139 PENIMLVDQ----------TRCPFRVK-----VIDFGSASIFSEVRYVKEPYIQSRFYRAPEILL 188

  Fly  1883 ELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARNHTLYSKTKTKYF 1947
            .|.:.:..||||:||::.||:||..|:..::..:.:..:....|     :.:.|.|::..|..:|
Mouse   189 GLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQG-----LPKPHLLHAARKAHHF 248

  Fly  1948 Y------HGKLDWDEKSSAGRYVRDHCKPL-----FLCQLSDSE--------------------D 1981
            :      .....|..||||........:||     .|..|...|                    :
Mouse   249 FKRNPHPDATNPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGGAVSRLSFPDREALAE 313

  Fly  1982 HCELFS---LIKKMLEYEPSSRITLGEALHHPFFD---------------------RL------- 2015
            |.:|.|   |||:||.:|...||:...||.|||..                     ||       
Mouse   314 HADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRSAHEATRYYQLSLRGCRLSLQVDGK 378

  Fly  2016 ------------PPHHRVGEVSNKQPL----SSGSSSRE 2038
                        ||::|:.|......|    .|||..||
Mouse   379 PPPPVIASAEDGPPYYRLAEEEETAGLGGVTGSGSFFRE 417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DoaNP_001014681.2 PKc_CLK 1679..2012 CDD:271036 108/357 (30%)
S_TKc 1692..2012 CDD:214567 108/357 (30%)
Hipk4NP_001028487.2 PKc_like 11..347 CDD:304357 108/357 (30%)
S_TKc 11..347 CDD:214567 108/357 (30%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 487..616
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0667
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.