Protein Alignment Doa and HIPK4

DIOPT Version :9

• Sequence 1: NP_001014681.2
• Gene: Doa / 43415
• FlyBaseID: FBgn0265998
• Length: 2045
• Species: Drosophila melanogaster
• Sequence 2: XP_006723099.1
• Gene: HIPK4 / 147746
• HGNCID: 19007
• Length: 619
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 118/393 - (30%)
• Similarity: 181/393 - (46%)
• Gaps: 71/393 - (18%)

  Fly  1692 YKIMATLGEGTFGRVVKVKDMERDYCMALKIIKNVEKYR-EAAKLEINALEKIAQKDPHCDHLCV 1755
            |.|:..||:||||.|.|.........:|:||:|| :.|| ...|.|:..|..:...||...|: :
Human    11 YDIIEVLGKGTFGEVAKGWRRSTGEMVAIKILKN-DAYRNRIIKNELKLLHCMRGLDPEEAHV-I 73

  Fly  1756 KMIDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLK 1820
            :.:::|.......:|||:|..::|:|.:|||:.|.|...:|.:..|:..::..|.:..:.|.|||
Human    74 RFLEFFHDALKFYLVFELLEQNLFEFQKENNFAPLPARHIRTVTLQVLTALARLKELAIIHADLK 138

  Fly  1821 PENILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHH---STIVSTRHYRAPEVIL 1882
            ||||:.||.          .|...|||     :||||||:...|..   ...:.:|.|||||::|
Human   139 PENIMLVDQ----------TRCPFRVK-----VIDFGSASIFSEVRYVKEPYIQSRFYRAPEILL 188

  Fly  1883 ELGWSQPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARNHTLYSKTKTKYF 1947
            .|.:.:..||||:||::.||:||..|:..::..:.:..:....|     :.:.|.|::..|..:|
Human   189 GLPFCEKVDVWSLGCVMAELHLGWPLYPGNNEYDQVRYICETQG-----LPKPHLLHAACKAHHF 248

  Fly  1948 Y------HGKLDWDEKSSAGRYVRDHCKPL-----FLCQLSDSE--------------------D 1981
            :      .....|..||||........:||     .|..|...|                    :
Human   249 FKRNPHPDAANPWQLKSSADYLAETKVRPLERRKYMLKSLDQIETVNGGSVASRLTFPDREALAE 313

  Fly  1982 HCELFS---LIKKMLEYEPSSRITLGEALHHPF--FDRLPPHHRVGEVSNKQPLSSGSSSRERSH 2041
            |.:|.|   |||:||.:|...||:...||.|||  ..:|...|   |.::...||.      ||:
Human   314 HADLKSMVELIKRMLTWESHERISPSAALRHPFVSMQQLRSAH---ETTHYYQLSL------RSY 369

  Fly  2042 SLS 2044
            .||
Human   370 RLS 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doa	NP_001014681.2	PKc_CLK	1679..2012	CDD:271036	109/359 (30%)
		S_TKc	1692..2012	CDD:214567	109/359 (30%)
HIPK4	XP_006723099.1	PKc_like	11..347	CDD:304357	108/357 (30%)
		S_TKc	11..347	CDD:214567	108/357 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810