Protein Alignment Doa and LOC1277360

DIOPT Version :10

• Sequence 1: NP_001014681.2
• Gene: Doa / 43415
• FlyBaseID: FBgn0265998
• Length: 2045
• Species: Drosophila melanogaster
• Sequence 2: XP_061505554.1
• Gene: LOC1277360 / 1277360
• VectorBaseID: AGAMI1_010544
• Length: 1224
• Species: Anopheles gambiae
• Alignment Length: 1241
• Identity: 425/1241 - (34%)
• Similarity: 582/1241 - (46%)
• Gaps: 329/1241 - (26%)

  Fly  1007 SMTHVPGGGQPMGAPLLRTSSRTHIPSYMKNLPSLSRSTSNSAILMTQPRKEP------------ 1059
            |.|...||..|       |::|..|......:.:|:|:.||:.:........|
Mosquito    47 SGTETAGGQVP-------TAARLQIAPLGYRVGNLARNVSNNWLSNGSNGSSPTTTTTSFAAIRQ 104

  Fly  1060 ---PPKEPLKAPAPLPAIAAPTVGKPSGVLKSSSSSCVPSPRC-----AAAFFRRPQEANNPQQQ 1116
               ...:....|:..|.....|||          ....|:.||     |.|....|.....|:|
Mosquito   105 QKISSSQEQHGPSGRPGTTTTTVG----------GKQQPTDRCAVHRAAGALAAVPPAKKLPEQ- 158

  Fly  1117 HHQPLQKPQQVAPIEESGPGDSASLERKSEKS--NSTLSTSSF-TVTNCCTTHLPQLSKFTSSFH 1178
                   |....|:.:| |...|...|..|.:  |..|:|||| ||....|:|           |
Mosquito   159 -------PIGDTPLLQS-PRIIARSARIVEPNAWNRRLTTSSFCTVAGTATSH-----------H 204

  Fly  1179 IAP----------TTATTTAATATPTPTGAATTSDQQQQSGGTPAMVAANLEVPTSSSSSAATKR 1233
            :.|          .....|..|...:|..:.|:.:........||....::..||::|::||.||
Mosquito   205 LHPHPHQQQQLPNNRFLQTPLTCRKSPGSSGTSVESIVPKYSRPAGNGGSVVEPTTTSTTAAQKR 269

  Fly  1234 ----------------------------------------------QKDVDNKLEKCL--NDMLK 1250
                                                          ..|.:.::.|.|  ::|..
Mosquito   270 TYNAHKPQLRVVSSRAHTNTTGRVGTVAKKATGPGCNAPIRTANVSPHDAEREVAKVLHQHNMRV 334

  Fly  1251 LKTSSNNNSTSNSNNNAIMSHSLTGEHKDPKTALEGPTSSSSSSSSKYIGESQIPVPVQLYDPQK 1315
            :...:||:..|......|..::   |:..|..::.|..:.......    .|.||..:.|.|.::
Mosquito   335 IDLLNNNHLQSQRGGRVIKENN---ENHQPAVSVNGGQNHQPGGKK----GSAIPQRLPLADREQ 392

  Fly  1316 PLLQQQQQQQRICYPIGKSNS------TSQLPMG-------GYQRLLQ-------HQQQQHHQQQ 1360
            |     .::.|....:|.:.|      :|:.|.|       .|:|..|       |:.::..::.
Mosquito   393 P-----TERNRRLPNVGGAGSGGSECFSSKFPNGLPFEQEFYYRRTGQDADTATLHEDKEEEEEG 452

  Fly  1361 QQQHQEQQQYPQHKRPFLNWNSFACSAMNGAS----DPFMQ----QQH--MPAHQQ--------- 1406
            :::.:|:::                 .|.|.|    |.:.:    ::|  :|..:|
Mosquito   453 EEEEEEEEE-----------------EMTGHSHLIADAYQRIRKAKKHALLPGRRQAGQIGGGVL 500

  Fly  1407 ---------QQHLPHKLQQSYSSSHVPKQAPKSGLAMFLQKNTNKENKF---------GQPMQQQ 1453
                     ||.|||:.:...||.....:..:......:::..:.|:..         .|.|:||
Mosquito   501 LAGRRVAMTQQELPHRSRSVSSSEGALHEDDRCRSVSAIEREHDDEDALYVDFTKVHDPQAMEQQ 565

  Fly  1454 PPGMMPQMYGYQAPQQQSKIGYPRTGA----PLTHSASF-------SSAQRPTALQFHQQHQQQQ 1507
                      .|..:|..:.| |:|..    .:.||:.:       |.|::..|.|.....:.:.
Mosquito   566 ----------QQRSKQHEEAG-PQTSVVEYRNINHSSYYYKFESISSHARKDPAGQRKLGQRSRA 619

  Fly  1508 HLQQQQQH-PQ-QQQHQHSSFGV-----------GMMSRNYY--NMPKQPERKPLQ--------- 1548
            ......:| |: :.::|.|..|:           |...|.||  ::..:|....|:
Mosquito   620 GADAGSEHRPELRSRYQRSRLGLNRTGTGKPDVNGNGGREYYDDDVSDEPGENGLEDHEGDGEEE 684

  Fly  1549 ----------------TFDPYAYPKPNQ---------------MQPVKY------QQQQQHPHTQ 1576
                            |:.|.....||:               :....|      |||||.| |:
Mosquito   685 DEEEEGERSTVYVAVATWVPKCNRLPNESSEHGNGNNNSICLTLATSSYGGEDIDQQQQQRP-TK 748

  Fly  1577 FQNASAGGGGGGAAGLQYDPNTNTQLFYASPASS--------------SSNKQPQQPQQQQQQQQ 1627
            ...|:........|.....|.:...:  ..|||:              ..|..|:.|
Mosquito   749 IGVAANHTAAATVAAAAVPPTSRKGV--PIPASTRHGQLNPDAGRWERERNNDPELP-------- 803

  Fly  1628 SQLQQSNSVIFNHSGQQHQPHQQQQNEMSKSALGLHFIETAKPVIQDDADGHLIYHTGDILHHRY 1692
               ..|.:.:..:.|::....|::|.|..:        :..:|.|:|||||||||..|||||:||
Mosquito   804 ---TTSRTAVPLNPGRRVTRLQRRQVEQQE--------DQKQPFIRDDADGHLIYQIGDILHNRY 857

  Fly  1693 KIMATLGEGTFGRVVKVKDMERDYCMALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKM 1757
            ||:||||||||||||||||:||::.|||||||||||||:||:|||.|||||.|.||:.:||||||
Mosquito   858 KILATLGEGTFGRVVKVKDLERNHVMALKIIKNVEKYRDAAELEIGALEKIMQLDPNLEHLCVKM 922

  Fly  1758 IDWFDYHGHMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPE 1822
            :||||||||.||.||||||||||||::|||||||::.|||::|||||:|||||::||||||||||
Mosquito   923 LDWFDYHGHTCIAFEMLGLSVFDFLKDNNYEPYPIEHVRHISYQLCYAVKFLHESRLTHTDLKPE 987

  Fly  1823 NILFVDSDYTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWS 1887
            |||||||:||:....:.|||||||..||:|||||||||||.||||||||||||||||||||||||
Mosquito   988 NILFVDSEYTTTTVPRKNREVRRVNCTDIRLIDFGSATFDDEHHSTIVSTRHYRAPEVILELGWS 1052

  Fly  1888 QPCDVWSIGCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARNHTLYSKTKTKYFYHGKL 1952
            |||||||||||:||||.|:|||.||||||||||||||||.|||||||      :|::|||.:|||
Mosquito  1053 QPCDVWSIGCIMFELYQGVTLFPTHDNREHLAMMERILGTIPYRMAR------QTRSKYFRYGKL 1111

  Fly  1953 DWDEKSSAGRYVRDHCKPLFLCQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPP 2017
            |||||||.||||||:||||..|.::|..||.:||.||:||||||||.||||.:||.||||.:||.
Mosquito  1112 DWDEKSSTGRYVRDNCKPLHRCVITDKPDHLQLFDLIRKMLEYEPSKRITLDKALRHPFFAKLPA 1176

  Fly  2018 HHRVGE 2023
            |.|:.|
Mosquito  1177 HQRLHE 1182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doa	NP_001014681.2	PHA03247	<205..634	CDD:223021
		PKc_CLK	1679..2012	CDD:271036	258/332 (78%)
LOC1277360	XP_061505554.1	None