Protein Alignment Doa and Clk3

DIOPT Version :9

• Sequence 1: NP_001014681.2
• Gene: Doa / 43415
• FlyBaseID: FBgn0265998
• Length: 2045
• Species: Drosophila melanogaster
• Sequence 2: XP_036010394.1
• Gene: Clk3 / 102414
• MGIID: 1098670
• Length: 507
• Species: Mus musculus
• Alignment Length: 645
• Identity: 257/645 - (39%)
• Similarity: 344/645 - (53%)
• Gaps: 163/645 - (25%)

  Fly  1390 GASDPFMQQQHM---PAHQQQQHL-----PH-----KLQQSYSSSHVPKQAPKSGLAMFLQKNTN 1441
            |.:.|.:|...:   |.|..:::.     |:     |.::|||..|
Mouse     2 GQTKPGVQMSRLLLGPMHHCKRYRSPEPDPYLSYRWKRRRSYSREH------------------- 47

  Fly  1442 KENKFGQPMQQQPPGMMPQMYGYQAPQQQSKIGYPRTGAPLTHSASFSSAQRPTALQFHQQHQQQ 1506
             |.:...|.:::||                    ||.....:|       .|....:.:::|:..
Mouse    48 -EGRLRYPSRREPP--------------------PRRSRSRSH-------DRIPYQRRYREHRDS 84

  Fly  1507 QHLQQQQQHPQQQQHQHSSFGVGMMSRNYYNMPKQPERKPLQTFDPYAYPKPNQMQPVKYQQQQQ 1571
            ...:.:::.|        |||     .:.|...:...|:           :..:..|.:.::...
Mouse    85 DTYRCEERSP--------SFG-----EDCYGSSRSRHRR-----------RSRERAPYRTRKHAH 125

  Fly  1572 HPHTQFQNASAGGGGGGAAGLQYDPNTNTQLFYASPASSSSNKQPQQPQQQQQQQQSQLQQSNSV 1636
            |.|.:...:                        .|.|||.|             |||..:.|.||
Mouse   126 HCHKRRTRS------------------------CSSASSRS-------------QQSSKRSSRSV 153

  Fly  1637 IFNHSGQQHQPHQQQQNEMSKSALGLHFIETAKPVIQDDADGHLIYHTGDILHHRYKIMATLGEG 1701
                                                :||.:|||:...||.|..||:|:..||||
Mouse   154 ------------------------------------EDDKEGHLVCRIGDWLQERYEIVGNLGEG 182

  Fly  1702 TFGRVVKVKDMERDYC-MALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHG 1765
            |||:||:..|..|... :|||||:||.||||||:||||.|:||.:||.....|||.|.|||::||
Mouse   183 TFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHG 247

  Fly  1766 HMCIVFEMLGLSVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSD 1830
            ||||.||:||.:.|:||:|||::||||..|||||||||::::|||:|:||||||||||||||:|:
Mouse   248 HMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLKPENILFVNSE 312

  Fly  1831 YTSHYNHKINREVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSI 1895
            :.:.||...:.|.:.||||.:|:.||||||||||||:|||:|||||.|||||||||:||||||||
Mouse   313 FETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHTTIVATRHYRPPEVILELGWAQPCDVWSI 377

  Fly  1896 GCILFELYLGITLFQTHDNREHLAMMERILGQIPYRMARNHTLYSKTKTKYFYHGKLDWDEKSSA 1960
            ||||||.|.|.||||||:|||||.|||:|||.||     :|.::...|.||||.|.|.|||.||.
Mouse   378 GCILFEYYRGFTLFQTHENREHLVMMEKILGPIP-----SHMIHRTRKQKYFYKGGLVWDENSSD 437

  Fly  1961 GRYVRDHCKPLFLCQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPFFDRLPPHHR 2020
            ||||:::||||....|.||.:|.:||.|:::|||::|:.||||.|||.||||..|.|..|
Mouse   438 GRYVKENCKPLKSYMLQDSLEHVQLFDLMRRMLEFDPAQRITLAEALLHPFFAGLTPEER 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doa	NP_001014681.2	PKc_CLK	1679..2012	CDD:271036	209/333 (63%)
		S_TKc	1692..2012	CDD:214567	203/320 (63%)
Clk3	XP_036010394.1	PKc_CLK3	159..489	CDD:271116	210/334 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	483	1.000	Domainoid score	I404
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000672
OrthoInspector	1	1.000	-	-		otm42815
orthoMCL	1	0.900	-	-		OOG6_100708
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R660
SonicParanoid	1	1.000	-	-		X440
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.840