Protein Alignment Doa and dyrk3

DIOPT Version :9

• Sequence 1: NP_001014681.2
• Gene: Doa / 43415
• FlyBaseID: FBgn0265998
• Length: 2045
• Species: Drosophila melanogaster
• Sequence 2: NP_001108400.1
• Gene: dyrk3 / 100141364
• ZFINID: ZDB-GENE-080219-31
• Length: 581
• Species: Danio rerio
• Alignment Length: 481
• Identity: 137/481 - (28%)
• Similarity: 226/481 - (46%)
• Gaps: 83/481 - (17%)

  Fly  1595 DPNTNTQLFYASPASSSSNK--------QPQQPQQQQQQQQSQLQQSNSVIFNHS-----GQQHQ 1646
            |.|::.:      :|.||.|        .|:|..:|.:||.:.|:|..  |.|:|     |...:
Zfish   111 DSNSSVK------SSESSTKVTKLGSPMTPEQALKQHRQQMTTLEQQE--IHNYSEIYFLGPNAK 167

  Fly  1647 PHQQQQNEMSKSALGLHFIETAKPVIQDDADGHLIYHTGDILHHRYKIMATLGEGTFGRVVKVKD 1711
            ..|......:.|.             .||..|..|:...|.|.:||:.:..:|:|:||:|.||.|
Zfish   168 KRQAVAGGTNNSG-------------YDDDQGGYIHVPHDHLAYRYEFLKVIGKGSFGQVAKVYD 219

  Fly  1712 MERDYCMALKIIKNVEKYREAAKLEINALEKIAQKDPHCDHLCVKMIDWFDYHGHMCIVFEMLGL 1776
            .:....:||||::|.:::...|..||..||.:.::|.......|.|::.|.:..|:|:.||:|.:
Zfish   220 HKLQQHVALKIVRNEKRFHRQAAEEIRILEHLKKQDKTGSMNVVHMLENFTFRNHICMTFELLSM 284

  Fly  1777 SVFDFLRENNYEPYPLDQVRHMAYQLCYSVKFLHDNRLTHTDLKPENILFVDSDYTSHYNHKINR 1841
            ::::.::.|.::.:.|..||..|:.:...::.||.:::.|.||||||||
Zfish   285 NLYELIKRNKFQGFSLPLVRKFAHSILQCLEALHRHKIIHCDLKPENIL---------------- 333

  Fly  1842 EVRRVKNTDVRLIDFGSATFDHEHHSTIVSTRHYRAPEVILELGWSQPCDVWSIGCILFELYLGI 1906
             :::...:.:::|||||:.|||:...|.:.:|.||||||||...:..|.|:||.||||.||..|.
Zfish   334 -LKQQGRSGIKVIDFGSSCFDHQRVYTYIQSRFYRAPEVILGSRYGMPIDMWSFGCILAELLTGY 397

  Fly  1907 TLFQTHDNREHLAMMERILGQIPYRM------------ARNHTLYSKTKTKYFYHGKLDWD-EKS 1958
            .||...|..:.||.|..:||..|.::            ::.|..|....|  ..:|.:..: .:|
Zfish   398 PLFPGEDEGDQLACMMELLGMPPSKLLEQAKRAKNFISSKGHPRYCTVST--LSNGTIVLNGSRS 460

  Fly  1959 SAGRYVRDHCKPLFLCQLSDSEDHCELFSLIKKMLEYEPSSRITLGEALHHPF-FDRLPPHHRVG 2022
            ..|:.........:...|...|| ......:||.|:::||:|:|..:||.||: :.|||
Zfish   461 RRGKMRGAPGSKEWGTALKGCED-ATFIDFLKKCLDWDPSTRMTPVQALRHPWLYKRLP------ 518

  Fly  2023 EVSNKQPLSSGSSS----RERSHSLS 2044
                 :|...|..:    |...||.|
Zfish   519 -----KPAPGGEKTVLPKRISEHSTS 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doa	NP_001014681.2	PKc_CLK	1679..2012	CDD:271036	106/346 (31%)
		S_TKc	1692..2012	CDD:214567	102/333 (31%)
dyrk3	NP_001108400.1	PKc_DYRK2_3	134..513	CDD:271126	122/413 (30%)
		S_TKc	200..513	CDD:214567	102/332 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0667
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810