DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33203 and ADIPOR1

DIOPT Version :9

Sequence 1:	NP_001138119.2	Gene:	CG33203 / 43414	FlyBaseID:	FBgn0053203	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_001277482.1	Gene:	ADIPOR1 / 51094	HGNCID:	24040	Length:	375	Species:	Homo sapiens

Alignment Length:	281	Identity:	86/281 - (30%)
Similarity:	127/281 - (45%)	Gaps:	58/281 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   173 QLLPWQDMPTYLQFNPYVLRGYR-PLQTFKGCLLSLFYWHNESINILTHAI--PIFYILAIVPGL 234
            :::|:..:|.:|:.|.|:|.|:| |:.:|:.|..|:|..|.|:.||.||.:  .:|..|.|:..|
Human    93 RVIPYDVLPDWLKDNDYLLHGHRPPMPSFRACFKSIFRIHTETGNIWTHLLGFVLFLFLGILTML 157

  Fly   235 MPWDSGYKFLSFCH---VFGSV---APWCGSFVYHLFMNIE-KGENVYYTLLKLDMVGI------ 286
            .|   ...|::...   |||..   |..|.||.: ||..:. ..|.|..|..|||..||
Human   158 RP---NMYFMAPLQEKVVFGMFFLGAVLCLSFSW-LFHTVYCHSEKVSRTFSKLDYSGIALLIMG 218

  Fly   287 ----WVSQSFGALPLVTATTLCFP-PVLKWLIIVSYCVLSLWGLYKALTASSPWQRRLCFALPFA 346
                |:..||          .|.| |.|.:|.||  |||.:..:..|     .|.|   ||.|..
Human   219 SFVPWLYYSF----------YCSPQPRLIYLSIV--CVLGISAIIVA-----QWDR---FATPKH 263

  Fly   347 MRS---ILTFLRIRGMVGGSHMALSHVYLQVEVDG----------VSILGGAIGAMRIPEKWFPG 398
            .::   :...|.:.|:|...|..::..:::....|          :.|.|..:.|.||||::|||
Human   264 RQTRAGVFLGLGLSGVVPTMHFTIAEGFVKATTVGQMGWFFLMAVMYITGAGLYAARIPERFFPG 328

  Fly   399 VVDFYLNSHNIMHVLVVVAVY 419
            ..|.:..||.|.|||||.|.:
Human   329 KFDIWFQSHQIFHVLVVAAAF 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33203	NP_001138119.2	HlyIII	208..421	CDD:296067	74/245 (30%)
ADIPOR1	NP_001277482.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..60
ADIPOR1	NP_001277482.1	HlyIII	129..352	CDD:397239	74/245 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53658
OrthoDB	1	1.010	-	-		D1524940at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.930