Protein Alignment Nepl21 and Ece1

DIOPT Version :9

• Sequence 1: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: XP_006239337.1
• Gene: Ece1 / 94204
• RGDID: 620293
• Length: 769
• Species: Rattus norvegicus
• Alignment Length: 712
• Identity: 207/712 - (29%)
• Similarity: 318/712 - (44%)
• Gaps: 111/712 - (15%)

  Fly    52 TAEIESFMDQKADPCNDFYAFSCGNYKRINSALSMQVVTTGVFETLTKGLNRKILKMLNTPHDSH 116
            |:.|.:.||...|||.||::::||.:.:.|...... ...|.|..|.:. |:.|:|.|.....:.
  Rat   107 TSSILNSMDPTVDPCQDFFSYACGGWIKANPVPDGH-SRWGTFSNLWEH-NQAIIKHLLENSTAS 169

  Fly   117 DTPEDIKVKHFYESCLQIKELNSTYSEKLKRLIAEFG----TMPLLEGSSWQEDDFDWLNTTARM 177
            .:..:.|.:.:|.:|:....:....::.|..||.:.|    |.|      |.:|:|.  :|...:
  Rat   170 ASEAEKKAQVYYRACMNETRIEELRAKPLMELIEKLGGWNITGP------WAKDNFQ--DTLQVV 226

  Fly   178 AYRYGITPIFGIEVNKDLASNTRNRIYLGQQDFPLEARSMYVDDATAVYRQKYRNNIQRILQRYL 242
            ...|..:|.|.:.|:.|..::..|.|.:.|....|.:|..|::        |..|  :::|..||
  Rat   227 TAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLN--------KTEN--EKVLTGYL 281

  Fly   243 GVKMDLAK-----------KTAKELIDFEVDLAQGLVDESEGLDVGELTQLLTVDEIQR-----R 291
            ...:.|.|           ...::::|||..||...:.:.:..|...:...:|..|:|.     .
  Rat   282 NYMVQLGKLLGGGDEDSIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAIN 346

  Fly   292 YSPTLDIDRLLFVSMGERISDQIYEYNNRYQQNLVEVIKRTPKRTVANYIFFRLIWEFVETPS-- 354
            :.|.|:   .:|..:....|:.|..|:..|.:.:..:|..|.|..:.||    ::|..|...|
  Rat   347 WLPFLN---AIFYPVEINESEPIVVYDKEYLRQVSTLINSTDKCLLNNY----MMWNLVRKTSSF 404

  Fly   355 ------DSPEKQM--------------KACVDLTKKYFAKNLDNMFYRRYNNEKSSREIDNMWRQ 399
                  |:.||.|              |.||..|:......|..||.:....|.|......:..:
  Rat   405 LDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNIASEIILE 469

  Fly   400 LKSTFNETLRSSPALNWIERPTRNLAMAKLQAMTLEVNNYADDNFTEEFAELNLQSDDYV----- 459
            :|..|.|:|.:   |.|::..||..|..|..|:   .|.....||..:..||:...:||.
  Rat   470 IKKAFEESLST---LKWMDEDTRRSAKEKADAI---YNMIGYPNFIMDPKELDKVFNDYTAVPDL 528

  Fly   460 --ENV----RYTSLLGAKQMREMLHKPAKPFEAGSQLSYTPANI-----LIENTIKVPVALLQ-P 512
              ||.    .::..:.|.|:|:..::        .|.|.||..:     ..:|.|..|..:|| |
  Rat   529 YFENAMRFFNFSWRVTADQLRKAPNR--------DQWSMTPPMVNAYYSPTKNEIVFPAGILQAP 585

  Fly   513 FYIWSDVYPNAIMFGTLASLIGHELIHGFDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQY 577
            ||..|.  |||:.||.:..::||||.|.|||.||::|:.||.:.||...|...|.::.:|..:||
  Rat   586 FYTRSS--PNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTECMVQQY 648

  Fly   578 GRYVYDGIQLKESTAQSENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQL 642
            ..|..:|..:.......||||||||::.||.||:.|.:.     |||:    :.||.|..|:.||
  Rat   649 NNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKK-----NGAE----QILPTLGLTSNQL 704

  Fly   643 FFISFAQSWCNDAHPSVKALQVSTDQHMPGRFRVIGSLSNFEEFSKEFNCPAGSAMNPSEKC 704
            ||:.|||.||:...|......:.||.|.|.||||||||||.:|||:.|.||.||.|||..||
  Rat   705 FFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPLGSPMNPRHKC 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl21	NP_651646.2	PepO	57..707	CDD:226118	205/707 (29%)
		M13	63..704	CDD:189000	201/699 (29%)
Ece1	XP_006239337.1	PepO	105..769	CDD:226118	207/712 (29%)
		M13	118..767	CDD:189000	203/701 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344488
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.950