Protein Alignment Nepl21 and Nepl18

DIOPT Version :9

• Sequence 1: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_651643.1
• Gene: Nepl18 / 43410
• FlyBaseID: FBgn0039611
• Length: 682
• Species: Drosophila melanogaster
• Alignment Length: 705
• Identity: 250/705 - (35%)
• Similarity: 394/705 - (55%)
• Gaps: 35/705 - (4%)

  Fly    11 QLLCICIAGHVLSAMVAAAPTSE---EDLKQDTPYMKELLRQAKTAEIESFMDQKADPCNDFYAF 72
            ::|.:|:...::.||...:...:   :||..|  |.|:::.|||.||:::.|..:..||:|||..
  Fly     5 RVLWLCLLVAIVPAMAKPSDAGDPFADDLTSD--YAKKIIVQAKVAEMKTMMKPEVSPCDDFYTH 67

  Fly    73 SCGNYKRINSALSMQVVTTGVFETLTKGLNRKILKMLNTPHDSHDTPEDI--KVKHFYESCLQIK 135
            :|||:.|.|.|..:..|.|..|:.::||.:|::.::|.    ::|...::  |::.||.||..:.
  Fly    68 ACGNWHRHNPAQLLGDVMTDNFKLISKGFDRRLQRLLR----ANDLQSELEKKMQRFYMSCNLVH 128

  Fly   136 ELNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDFDWLNTTARMAYRYGITPIFGIEVNKDLASNTR 200
            ..:..|...|:.:|.|:||:|.|.|:.|...||.|..|.|::.::||...|.|:|:..|:.:.:.
  Fly   129 RDDVHYKLALENVIREYGTLPALVGAQWNSSDFSWWRTVAQIQHKYGKQIIIGLEIMHDIRNTSV 193

  Fly   201 NRIYLGQQDFPLEARSMYVDDATAVYRQKYRNNIQRILQRYLGVKMDLAKKTAKELIDFEVDLAQ 265
            ||:|:.|.||..      ::.......::.|.::.  ||:|.|:...:||.||::|.:.|...:.
  Fly   194 NRVYISQPDFKT------INTRLTNLMEEVRTSMD--LQQYFGLSSSVAKHTAEQLTELERTFSS 250

  Fly   266 GLVDESEGLDVGELTQLLTVDEIQRRYSPTLDIDRLLFVSMG-ERISDQIYEYNNRYQQNLVEVI 329
            |   .|....:.|...|.||.::|.:||..|:....|.:.:| |.|...:|.|:..|....:..:
  Fly   251 G---GSGAATLQESLSLYTVADLQEKYSDHLNFTEFLGLILGEENIPKSLYIYDEEYLDKALLTM 312

  Fly   330 KRTPKRTVANYIFFRLIWEFVETPSDSPEKQMKACVDLTKKYFAKNLDNMFYRRYNNEKSSREID 394
            :.||..|.|||:.::|:.:|:  ....|:..:|.|.:.|||||.|..::..|:||.|.....|:.
  Fly   313 RSTPLATQANYVLWKLLEDFL--VDAQPKDMVKWCTESTKKYFGKLAEHAVYKRYRNPDVESEVH 375

  Fly   395 NMWRQLKSTFNETLRSSPALNWIERPTRNLAMAKLQAMTLEVNNYADDNFTEEFAELNLQSDDYV 459
            .:|.|:|..|.:.|... .|:||...||.||:.||:.|.|.:|:|.::||...:.|:.:...:||
  Fly   376 KIWDQIKGIFRQRLLGD-KLDWISNATRTLAIEKLERMHLNINSYDEENFENVYGEVFIDRLNYV 439

  Fly   460 ENVRYTSLLGAKQMR--EMLHKPAKPFEAGSQLSYTPANILIENTIKVPVALLQPFYIWSDVYPN 522
            .||:  .||.||.:|  ..:::||...:|...|.:|||..:.||.|.:|||||||.|.|.|.||.
  Fly   440 SNVQ--QLLIAKGIRFVARINQPADSVDATELLGFTPAYNIQENNITIPVALLQPRYFWGDQYPE 502

  Fly   523 AIMFGTLASLIGHELIHGFDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQYGRYVYDGIQL 587
            |:.:.||..|:.||::|||||.||::|..||...|||.||...|.:||.||..||..|.|.|.:|
  Fly   503 ALKYATLGYLLAHEMLHGFDDDGRQYDASGNLAPWWDLKSRYEFEERRKCFQAQYHEYQYGGSKL 567

  Fly   588 KESTAQSENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWC 652
            .||..|||||||:||::|||.||..|...|     ..:.:.:||:..|.:.::||||:.:||..|
  Fly   568 PESKDQSENIADSGGLKLAYAAYELWLGQQ-----SEEVLQRETMEGLPFNSRQLFFLGYAQLLC 627

  Fly   653 NDAHPSVKALQVSTDQHMPGRFRVIGSLSNFEEFSKEFNCPAGSAMNPSEKCILY 707
            :|.....:.....:|:|.|.::||||.||||:||...|||...:.|:|..||.:|
  Fly   628 DDVQFLFQPWVSQSDRHAPSKYRVIGPLSNFQEFPWVFNCSQSAPMDPEYKCAIY 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl21	NP_651646.2	PepO	57..707	CDD:226118	235/654 (36%)
		M13	63..704	CDD:189000	232/645 (36%)
Nepl18	NP_651643.1	PepO	54..682	CDD:226118	235/652 (36%)
		M13	58..679	CDD:189000	232/645 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451240
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	1	1.000	-	-		FOG0007609
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.950