Protein Alignment Nepl21 and Nepl17

DIOPT Version :10

• Sequence 1: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_651641.1
• Gene: Nepl17 / 43408
• FlyBaseID: FBgn0039609
• Length: 681
• Species: Drosophila melanogaster
• Alignment Length: 670
• Identity: 215/670 - (32%)
• Similarity: 358/670 - (53%)
• Gaps: 22/670 - (3%)

  Fly    40 TPYMKELLRQAKTAEIESFMDQKADPCNDFYAFSCGNYKRINSALSMQVVTTGVFETLTKGLNRK 104
            ||..::::|.||:||:.||||....||:|||.::||||..||:|.|.:  .|.:.:.:.....|:
  Fly    32 TPLGQQIMRIAKSAEMCSFMDTSVSPCDDFYGYACGNYATINAATSQK--DTNIRQLMFANYLRR 94

  Fly   105 ILKMLNTPHDSHDTPEDIKVKHFYESCLQIKELNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDFD 169
            :.::||.|..|.|.|.:::||:||||||....|.:.....|..::.|||.||.:||.||....||
  Fly    95 VRQVLNEPRISTDRPMEVRVKYFYESCLDTAALRTKQRSHLLSVLREFGGMPAVEGKSWDYVGFD 159

  Fly   170 WLNTTARMAYRYGITPIFGIEVNKDLASNTRNRIYLGQQDFPLEARSMYVDDATAVYRQKYRNNI 234
            .:...|::..|||...:.|:.|..|..::...|:.|||:      ..:...|..|...:||.  :
  Fly   160 AIEMMAQLLRRYGKLTLLGVYVVPDHFNSQIKRLQLGQR------LDLAESDEFASLWKKYA--L 216

  Fly   235 QRILQRYLGVKMDLAKKTAKELIDFEVDLAQGLVDESEGLDVGELTQLLTVDEIQRRYSPTLDID 299
            :..|:..||:..:||:|||:|:|:.|::|::...|.....|...:..|..:..:...|.|.|::.
  Fly   217 KMRLRNLLGLSEELARKTAEEIIELELELSRSAFDHRMNRDPRLMRHLTMLSNMSDAYGPILNVT 281

  Fly   300 RLLFVSMGERISDQIYEYNNRYQQNLVEVIKRTPKRTVANYIFFRLIWEFVETPSDSPEKQMKAC 364
            |.:...:|...:..::|....|...:.:::..||...||||:...|:.:|..|.::  |:|...|
  Fly   282 RFVTSWLGSEYNLPVFESVPSYLFQVKKILLSTPNHVVANYMLSSLLTDFEITANE--EQQKVIC 344

  Fly   365 VDLTKKYFAKNLDNMFYR--RYNNEKSSREIDNMWRQLKSTFNETLRSSPALNWIERPTRNLAMA 427
            .:...:.|...:|:|.|.  ...|...:.|:.::|.:|||:|.|.| |||.:.|:|:.||...:.
  Fly   345 HERITELFPDVVDHMVYHSLEQQNPYIANEMRSLWVELKSSFREML-SSPDIEWLEKQTREELLE 408

  Fly   428 KLQAMTLEVNNYADDNFTEEFAELNLQSDDYVENVRYTSLLGAKQMREMLHKPAKPFEAGSQLSY 492
            ||..|:.|:......||.|:|.:|.:.|.||..|::....:.|:.:|..|.:.:........::.
  Fly   409 KLNGMSFEIAGGQAVNFEEQFGDLVVSSADYYGNIQRLLEVKARILRTDLLRESSSVYYYHGVTA 473

  Fly   493 TPANILIENTIKVPVALLQPFYIWSDVYPNAIMFGTLASLIGHELIHGFDDSGRKFDEKGNSKDW 557
            ||......|.:.:||:.:|..|:|.|:||.|:.:|||...:.||:.|||||..|.:|.:||..|.
  Fly   474 TPIYETETNLVVLPVSYMQHRYLWDDIYPAALKYGTLGFTMAHEMAHGFDDLNRLYDSRGNLNDN 538

  Fly   558 WDEKSSSNFLKRRDCFTKQYGRYVYDGIQLKESTAQSENIADNGGMRLAYTAYRKWYENQLTLPN 622
            |..::...|...::|...|:...:|..::|:...:|:|:||||.|:|:|.:||.||.: |:.:..
  Fly   539 WSTQTKVGFELVKNCLADQFSGMLYGNLRLRRLKSQAESIADNVGIRIAQSAYWKWLD-QVEMEE 602

  Fly   623 GAQDMTKETLPNLRYTAKQLFFISFAQSWCNDAHPSVKALQVSTDQHMPGRFRVIGSLSNFEEFS 687
                  .|:||::..:.:||||:|.||..|:|.:|..:|..|..:.|.|...||...:.|...|:
  Fly   603 ------TESLPHMTQSPEQLFFLSAAQFMCSDIYPERRANFVRNNFHPPYEARVFAMMINSPAFA 661

  Fly   688 KEFNCPAGSAMNPSEKCILY 707
            :.|.|...|.|||..||::|
  Fly   662 EAFQCSNSSKMNPPNKCLMY 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl21	NP_651646.2	M13	63..704	CDD:341056	201/642 (31%)
Nepl17	NP_651641.1	M13	55..678	CDD:341056	201/642 (31%)