Protein Alignment Nepl21 and Nepl12

DIOPT Version :9

• Sequence 1: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_649924.1
• Gene: Nepl12 / 41172
• FlyBaseID: FBgn0037727
• Length: 702
• Species: Drosophila melanogaster
• Alignment Length: 735
• Identity: 189/735 - (25%)
• Similarity: 314/735 - (42%)
• Gaps: 140/735 - (19%)

  Fly    32 SEEDLKQDTPYMKELLRQAKTAEIESFMDQKADPCNDFYAFSCGNYKRI-------NSALSMQVV 89
            :|..|::...:||            |:|:|..:||.:||.::||||:.:       .|..::..|
  Fly    49 AEYQLQEYAEFMK------------SYMNQSVEPCENFYEYACGNYRNVKPDRYSPGSRSNLGDV 101

  Fly    90 TTGVFETLTKGLNR-KILKMLNTPHDSHDTPEDIKVKHFYESCL--QIKELNSTYSEKLKRLIAE 151
            |..:.:...:.|.| .:.:.||.      :.|....:.||.:||  .:...|:.....|. ||..
  Fly   102 TYTLIDITEQLLGRMDLAEALNV------SSELAVAQRFYNACLGANLHPFNAADPAYLS-LIRS 159

  Fly   152 FGTMPLLEGSSWQEDDFDWLNTTARMAYRYGITPIFGIEVNKDLASNTRNRIYLGQQDFPLEARS 216
            .|..|.::|.:|:..:|:|:|.:|.:| .||...:    :.:.|           |..:|.|..:
  Fly   160 IGGFPAVDGDAWKASNFNWINMSAHLA-NYGANGL----IRETL-----------QLRYPFEPYT 208

  Fly   217 MYVD---DATAVYRQKYRNNIQRILQ----------RYLGVKMDLAKKTAKELIDFEVDLAQGLV 268
            ...:   |...|:.:....|..|..:          |..|:..|..::....:..|..| |..:.
  Fly   209 KLPELGFDHIIVHEENISRNTTRAFRLNEERMHGYLRAFGLPEDRIREAIAGVFAFWRD-ALEIP 272

  Fly   269 DESEGLDVGELTQLLTVDEIQRRYSPTLDIDRLLFVSMGERISDQIYEYN---------NR---- 320
            .:.|..|...:.::....|                           |.||         |:
  Fly   273 PQCEVFDPYRIKRVFPQSE---------------------------YYYNISWSGLHSTNKLFCD 310

  Fly   321 -YQQNLVEVIKRTPKRTVANYIFFRLIWEFVETPSDSPEKQMKACVDLTKKYFAKNLDNMFYRRY 384
             |...|.:|..| .::.||||:..:|::.| :....:|..|...| .:|.....:.|.|..|...
  Fly   311 FYYVELDKVCAR-HRKAVANYLAMKLLYRF-DPKLKAPRYQRNYC-SVTLYQSMRFLFNKLYMAN 372

  Fly   385 NNEKSSR-EIDNMWRQLKSTFNETLRSSPALNWIERPTRNLAMAKLQAMTLEVNNYADDNFTE-- 446
            |..::.| |:..|.|:|:.:..:.|..:   :|::..:|..|:.|...:...:.::.||..::
  Fly   373 NFSEAKRLEMSEMVRELRKSLRKALEDA---DWLDAESRARALLKESRIQPRIGSFQDDALSDRI 434

  Fly   447 --EFAELNLQSDDYVE-NVRYTSLL------GAKQMREMLH--KPAKPFEAGSQLS---YTPANI 497
              |...|.:..|.|.| |:....|:      .::..:|:.:  ||.| ...|.|:.   |||
  Fly   435 IREINSLKVIEDRYAETNINLQHLVVQINRFSSRHFQELTNDTKPQK-ILTGLQVGAGYYTP--- 495

  Fly   498 LIENTIKVPVALLQPFYIWSDVYPNAIMFGTLASLIGHELIHGFDDSGRKFDEKGNSKDWWDEKS 562
              :|:|.|...:::| .|:....|.::.||||..::|||||||||.:...||..|:.:....|.|
  Fly   496 --DNSINVMAGVVEP-PIYQRHLPISLKFGTLGFIVGHELIHGFDTTSSYFDGNGHMESLLSEIS 557

  Fly   563 SSNFLKRRDCFTKQYGRYVYDGI--QLKESTAQSENIADNGGMRLAYTAYRKWYENQLTLPNGAQ 625
            ......|.:|:...||:|....|  ::...|...||||||.|:|.|.||||.  ..|..|.:..|
  Fly   558 QQALEDRAECYMDYYGKYQVPEISRRVNGKTTLDENIADNSGLRQALTAYRS--HRQQLLEHPGQ 620

  Fly   626 DMTKETLPNLRYTAKQLFFISFAQSWCN--DAHPSVKALQVSTDQHMPGRFRVIGSLSNFEEFSK 688
            :...:.:|.|..|.:||||:.|||.:|:  :.....|.|   :|.|...:|||:|.|||.|:|..
  Fly   621 ERISDAMPGLDLTPEQLFFLGFAQLFCSHYEEEHYWKGL---SDVHTFDQFRVLGVLSNSEDFFH 682

  Fly   689 EFNCPAGSAMNPSEK-CILY 707
            .:||..||.|.|..| |.|:
  Fly   683 AYNCSVGSGMRPGAKTCRLW 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl21	NP_651646.2	PepO	57..707	CDD:226118	184/708 (26%)
		M13	63..704	CDD:189000	180/699 (26%)
Nepl12	NP_649924.1	M13	68..700	CDD:189000	180/700 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451254
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950