Protein Alignment Nepl21 and Nepl11

DIOPT Version :9

• Sequence 1: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_649449.1
• Gene: Nepl11 / 40540
• FlyBaseID: FBgn0037230
• Length: 592
• Species: Drosophila melanogaster
• Alignment Length: 749
• Identity: 140/749 - (18%)
• Similarity: 255/749 - (34%)
• Gaps: 218/749 - (29%)

  Fly     9 AKQLLCICIAGHVLSAMVAAAPTSEEDLKQDTPYMKELLRQAKTAEIESFMDQKADPCNDFYAFS 73
            :|.|..:.|||        .|...::.|:.:|    |||  :.:..:|.::|....||.|||.:.
  Fly     3 SKALAVLWIAG--------IAYGQDDLLRVET----ELL--SFSHNLEPYLDTSKQPCQDFYGYV 53

  Fly    74 CGNYKRINSALSMQVVTTG--VFETLTKGLNRKILKMLNTPHDSHDTPEDIKVKHFYESCLQIKE 136
            |.:        |..:..||  .|::|.|  ...:.::::.         ::::.:|::||...:.
  Fly    54 CSH--------SANLSETGRQRFQSLLK--ETDVAQLMDM---------ELQLINFFKSCESGRG 99

  Fly   137 LNSTYSEKLKRLIAEFGTMPLLE-----GSSWQEDDFDWLNTTARMAYRYGITPIFGIEVNKDLA 196
            :.:....:|.|   :.|..|.||     .|........||..   :.|.:.:...:..|.:..:.
  Fly   100 VEALKGSQLYR---QSGGWPSLEPNKVNASQRTNQTQRWLGL---LGYFHEVGAPYFFETSVTMQ 158

  Fly   197 SNTRNRIYLGQQDFPLEARSMYVDDATAVYRQKYRNNIQRILQRYLGVKMDLAKKTAKELIDFE- 260
            ||.|..:             :..|.......:|:...:..:||.: |::...|..||.|::..|
  Fly   159 SNKRLVV-------------LQPDGTRRNTLRKFEQRVGEVLQSF-GIEQSRAHVTALEVLSLER 209

  Fly   261 --VDLAQGLVDESEGLDVGELTQLLTVDEIQRRYSP------------TLDID---RLLFVSMGE 308
              .|:.:  .|..|             |::|..|..            .||.|   |.|......
  Fly   210 SRRDIVK--ADHVE-------------DQVQFSYGNFKRIVFGNASLIRLDWDGYFRKLLGGKTP 259

  Fly   309 RISDQIYEYNNRYQQNLVE---VIKRTPKRTVANYIFFRLIWEFVETPSDSPEKQMKACVDLTKK 370
            :.||.|..   :....|||   :::.|....:.|:|:...:.:.|:..          |..|::.
  Fly   260 QASDTIVV---KQLPRLVEYFALLQNTSMVRLLNWIWTDYLMDIVDAD----------CHQLSET 311

  Fly   371 YFAKNLDNMFYRRYNNEKSSREIDNMWRQLKSTFNETLRSSPALNWIERPTRNLAMAKLQAMTLE 435
            |......::..|...|..   |:..|:.:|...:.:.|..|.   ||:                |
  Fly   312 YAGDLYAHVVQRVTANRV---ELAQMYSELGKAYTDQLGGSV---WID----------------E 354

  Fly   436 VNNYADDNFTEEFAELNLQSDDYVENVRYTSLLGAKQMREMLHKPAKPFEAGSQLS--------- 491
            ::..:...|........|..|:.::...::.|||.:.:...|.|..| |:...:|:
  Fly   355 ISRQSSRQFLGNIMHTTLNGDERLDAAYHSILLGRRSLYRNLEKLRK-FQRTRRLASHSAQQVRR 418

  Fly   492 ----YTPANILI-ENTIKVPVALLQPFYIWSDVYPNAIMFGTLASLIGHELIHGFDDSGRKFDEK 551
                :.|.|..: ::.:..|:              |.::.|...|              |.....
  Fly   419 YAQMFAPVNAFLGQHNLSTPL--------------NYLLLGEFFS--------------RSLVAA 455

  Fly   552 GNSK----DWWDEKSSSNFLKRRDCFTKQYGRYVYDGIQLKESTAQSENIADNGGMRLAYTAYRK 612
            |:|.    .|....|...|...:.|..||     .:.|.|..|..         ..|.|.:||.:
  Fly   456 GSSSRTQGAWRSSDSERRFAIFQQCVGKQ-----TNAIDLLLSLL---------AQRQALSAYGQ 506

  Fly   613 WYENQ--------LTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWCNDAHPSVKALQVSTDQH 669
            |...|        ..|..|:..|          :.::|||::   |...|....:.|||....:.
  Fly   507 WLATQAGLVERVDAVLAAGSSKM----------SLQRLFFVT---SLLVDCRSELGALQQDRKRQ 558

  Fly   670 MPGRFRVIGSLSNFEEFSKEFNCPAGSAMNPSEK 703
            :     ...:|.|..||.:.|.|..|..:.|.::
  Fly   559 V-----THATLRNSPEFLEAFRCRPGDVLYPQDQ 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl21	NP_651646.2	PepO	57..707	CDD:226118	128/701 (18%)
		M13	63..704	CDD:189000	127/695 (18%)
Nepl11	NP_649449.1	GluZincin	45..589	CDD:301352	127/693 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010