Protein Alignment Nepl21 and Nepl10

DIOPT Version :9

• Sequence 1: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_610787.1
• Gene: Nepl10 / 36366
• FlyBaseID: FBgn0033742
• Length: 633
• Species: Drosophila melanogaster
• Alignment Length: 769
• Identity: 156/769 - (20%)
• Similarity: 288/769 - (37%)
• Gaps: 228/769 - (29%)

  Fly    12 LLCICIAGHV--LSAMVAAAPTSEEDLKQDTPYMKELLRQAKTAEIESFMDQKADPCNDFYAFSC 74
            |||.|:....  :.|:|.                   :..|.:.:|.:.:::...||.:|:.|:|
  Fly     6 LLCSCLVALFIPIQAIVD-------------------INVATSNDIHNNLNRTTSPCTNFWNFAC 51

  Fly    75 GNYKRINSALSMQVVTTGVFETLTKGLNRKILKMLNTPHDSHDT--PEDIK-VKHFYESCLQIKE 136
            |.:    |:.|..|..   ||.:.......:::.:.:....:||  |..|| ::.:|::|
  Fly    52 GRF----SSASKYVDN---FERVEDQFATAMVEFMESHLGENDTLAPRLIKQMRQYYKAC----- 104

  Fly   137 LNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDFD-WLNTTARMAYRYGITPIFGIEVNKDLASNTR 200
                 .|..::          |.|:...|:..: |:....:... ||:..:| |:...|:|:|..
  Fly   105 -----KEDTRK----------LHGNPRPEELVNQWILHPKKFLV-YGLNGVF-IDERVDVAANDS 152

  Fly   201 NR--IYLGQQDFPLEARSMYVDDATAVYRQKYRNNIQRILQRYLGVKMDLAKKTAKELIDFEVDL 263
            .|  |.|...| |.:                 |.:.:|:||     .|.|.:         |...
  Fly   153 MRWVIQLRMPD-PAD-----------------RYSDRRVLQ-----LMRLYE---------EAWY 185

  Fly   264 AQGLVDESEGLDVGELTQLLTVDEIQRRY-----------SPTLDIDRLLFVS-MGERISDQIYE 316
            :.|:|...|     ::.||  .|:.:..|           ...:.|....|:. :|...::::|.
  Fly   186 SMGVVKLVE-----KMHQL--QDKYRAEYPVVYTWSFSELRQEIPIPHSFFIELLGVNHTEELYH 243

  Fly   317 YNNRYQQNLVEVIKRTPKRTVANYIFFRLIWEFVETPSDS---------------PEKQMKACVD 366
            ..  ::.:.||.::..          ||.:.:|...|.|:               .|:..::|:.
  Fly   244 LT--FEVSDVEYLREC----------FRCLRDFASEPKDTYIRARQYVLVEESEPRERNPRSCIH 296

  Fly   367 LTKKYFAKNLDNMFYRRY---NNEKSSREIDNMWRQLKSTFNETLRSSPALNWIERPTRNLA--M 426
            ..:.|....: |..|.|:   |.|:.:.::..:...||:.|.:.|.:    |.::.....||  .
  Fly   297 HMRAYLPLGM-NYIYDRFIYQNREEDTSKVLEILSTLKAAFGQYLDA----NRLQLTPNQLAYVR 356

  Fly   427 AKLQAMTLEVNNYADDN----FTEEFAELNLQSDDYVENVRYTSLLGAKQMREMLHKP---AKPF 484
            |||:.:.:::.|..::.    :...:...|..:.:::.|     ||.|..:|..|...   |:..
  Fly   357 AKLEGIQIKIGNLPEEKSPEFYNNHYGSANFSATNFLAN-----LLEAFALRTRLQNAGLLARNS 416

  Fly   485 EAGSQLSYTPANIL----------IENTIKVPVALLQ-PFYIWSD--VYPNAIMFGTLASLIGHE 536
            ....:..|...|:.          ..|||.||:..|| |.:...:  ::.:::    |.:::|||
  Fly   417 RVDLRHYYVNDNVRKARTSPFYENERNTITVPMEFLQWPLFDHREHTIFQHSL----LGAVLGHE 477

  Fly   537 LIHGFDDSGRKFDEKGN-SKDWWDEKSSSNFLKRRDCFTKQYGRYVYDGIQLKESTAQSENIADN 600
            :.|.|:..|..||..|| |....:.:.|..|.....|..:|      ..:.||      |.:||.
  Fly   478 MNHAFEQEGILFDAAGNESPVGLEIRESKPFRDAIKCAEEQ------PFVSLK------ERLADL 530

  Fly   601 GGMRLAYTA------------YRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWCN 653
            .|::|||.|            ||.:...|                  .:||.|||.:|:||.:|.
  Fly   531 NGLQLAYDAFFGLAHDSRQFEYRPYAFEQ------------------EFTAPQLFHLSYAQFFCG 577

  Fly   654 DAHPSVKALQVSTDQHMPGRFRVIGSLSNFEEFSKEFNCPAGSAMNPSEKCILY 707
            ...|.:        .|.....||..|:.|..:|:.:|||..    :||..|.::
  Fly   578 SLPPVI--------AHDRDDERVNVSVGNLRQFAYDFNCET----SPSSVCEMW 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl21	NP_651646.2	PepO	57..707	CDD:226118	148/720 (21%)
		M13	63..704	CDD:189000	147/711 (21%)
Nepl10	NP_610787.1	GluZincin	41..608	CDD:301352	143/698 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020