Protein Alignment Nepl21 and Nepl5

DIOPT Version :9

• Sequence 1: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_609022.1
• Gene: Nepl5 / 33892
• FlyBaseID: FBgn0031808
• Length: 684
• Species: Drosophila melanogaster
• Alignment Length: 747
• Identity: 176/747 - (23%)
• Similarity: 314/747 - (42%)
• Gaps: 176/747 - (23%)

  Fly    43 MKELLRQAKTAEIESFMDQKADPCNDFYAFSCGNYK---------------RINSALSMQVVTTG 92
            ::|:|.:    :::|:||.||.||.:||.::|||::               |.......|::.|.
  Fly    32 VQEMLAE----QLQSYMDTKARPCENFYQYACGNWQIQQQEQHSLRDRDWTRDRQRYQGQMLPTD 92

  Fly    93 VFETLTKGLNRKILKMLNTPHD-SHDTPEDI--KVKHFYESCLQIKELNSTYSEKLKRLIAEFGT 154
            ....:...:|||:..:|...:: |.::...|  :::.:|.||.::|..|  ..:.|:.|.....|
  Fly    93 TLGLIDHSVNRKLELLLRRRNESSFESDSSILEQMRLYYRSCKRLKPYN--LKKYLQLLPPSNST 155

  Fly   155 MPLLEGSSWQEDDFDWLNTTARMAYRYGITPIFGIEVNKDLA---SNTRN-RIYLG----QQDFP 211
            .....|..|:.:.|||:.|..|:.. :|:.   |:.:.:::.   .::|| .||:.    |:..|
  Fly   156 QWPSVGRGWRPERFDWITTLGRLRL-HGLN---GVLLREEVLPRWDDSRNYSIYVNKPSRQETQP 216

  Fly   212 LEARSMYVDDATAVYRQKYRNNIQRILQRYLGVKMDLAKKTAKELIDFEVDL--AQGLVDESEG- 273
            :...:|                |:.:|.  :|.....|...|:::.|||..|  .|.|.|: ||
  Fly   217 MGEGAM----------------IELLLD--IGQTKRTANALARQVDDFERKLHRLQELEDD-EGP 262

  Fly   274 -------LDVGELTQLLTVDEI-QRRYSPTLDIDRLLFVSMGERISDQIYEYNNRYQQNLVEVIK 330
                   || ..|.||..:..: |.|....||:...|.:.            |..|.:.|.::::
  Fly   263 REMQLGYLD-SYLPQLRWLSFMRQVRIDSELDLRSTLIIE------------NIPYLRALSDLME 314

  Fly   331 RTPKRTVANYIFFR-LIWEFVETPSDSPEKQMKACVDLTKKYFAKNLDNMFYRRYNNEKSSREID 394
            .....||.:||..: |.:...:.|:|....:   ||...::........:..:::::.:|...:.
  Fly   315 SESPDTVCSYIMLKWLAFLKQQGPADISRGE---CVAALRRAMPLASSWLVGQQFSDPESESYVS 376

  Fly   395 NMWRQLKSTFNETL-----RSSPALNWIERPTRNLAMAKLQAMTLEVNNYADDNFTEEFAE---- 450
            :::::||..|.:.|     |.||       |..::...||:|:.|::..:.    |||..:
  Fly   377 SLFQRLKVRFGQILAENRMRLSP-------PLVHILQQKLRAVRLQMGFFQ----TEEIEDVEQY 430

  Fly   451 ---LNLQSDDYVENVRYTSLLGAKQMREMLHKPAKPF--EAGSQLSY----------TPANILIE 500
               ::|....:..|.........:...::|:.....|  ..||.|||          :|..:...
  Fly   431 HVRIDLSGHSFYGNQLVLLRQRVEANHDLLYINVTNFANSTGSNLSYLSESWEASNSSPLYVRPR 495

  Fly   501 NTIKVPVALLQPFYIW----SDVYPNAIMFGTLASLIGHELIHGFDDSGRKFDEKGNSKDWWDE- 560
            |.:.||..||| ..||    |.:..:|:|...||    |||.||||..|..:|..||.....:|
  Fly   496 NLVLVPHGLLQ-LPIWHRNISALQQHAVMGFVLA----HELAHGFDMLGMDYDAMGNIMGPVEEI 555

  Fly   561 KSSSNFLKRRDCFTKQY---GRYVYDGIQLKESTAQSENIADNGGMRLAYTAYRKWYENQLTLPN 622
            .:|..|.:...|..:|.   .:::            .|.:||...:||||..:           .
  Fly   556 GASRQFRQGLQCLQQQMATGSKWI------------DEKLADFVALRLAYETF-----------F 597

  Fly   623 GAQDMTKETLPNL-RYTAKQLFFISFAQSWC-----------NDAHPSVKALQVSTDQHMPGRFR 675
            |.:|..:...|.| :::.:|||||:|||.:|           ::||.          :|.....|
  Fly   598 GVRDKREPRDPLLPQFSQRQLFFITFAQFFCGRTPVLSPRSQSEAHL----------KHAADELR 652

  Fly   676 VIGSLSNFEEFSKEFNCPAGSAMNPSEKCILY 707
            |:.:|:||||||:||.|...:.|..|::|.::
  Fly   653 VMQTLANFEEFSREFGCDKKAKMQASQRCRIW 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl21	NP_651646.2	PepO	57..707	CDD:226118	174/731 (24%)
		M13	63..704	CDD:189000	169/722 (23%)
Nepl5	NP_609022.1	PepO	42..684	CDD:226118	174/731 (24%)
		GluZincin	48..682	CDD:301352	169/723 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454898
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950