Protein Alignment Nepl21 and Kel

DIOPT Version :9

• Sequence 1: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_001178540.1
• Gene: Kel / 297025
• RGDID: 1565470
• Length: 713
• Species: Rattus norvegicus
• Alignment Length: 699
• Identity: 175/699 - (25%)
• Similarity: 290/699 - (41%)
• Gaps: 111/699 - (15%)

  Fly    60 DQKADPCNDFYAFSCGNYKRINSALSMQVVTTGVFETLTKGLNRKILKMLNTPHDSHDTPEDIKV 124
            ::.|.||.||::|:|   ::.|.       |:..|:.|.:....::.|:|..|...|....:.|.
  Rat    75 NRSAAPCTDFFSFAC---EKANG-------TSNSFQALAEENKSRLWKLLEAPGSWHLESGEEKA 129

  Fly   125 KHFYESCLQIKELNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDFDWLNTTARMAY-RYGITPIFG 188
            ..||.||:....:.::.:..|.::|.|.|...:  ..:|...||   |...|:.. :||..|.|.
  Rat   130 FQFYNSCMDTDAIEASGTGPLVQIIKELGGWNI--SGNWTFFDF---NQNLRLLMSQYGHFPFFR 189

  Fly   189 IEVNKDLASNTRNRIYLGQQDFPLEARSMYVDDATAVYRQKYRNNIQRI--LQRYLGVKMDLAKK 251
            ..::...|......|.:.|.:|.:   .:..|....||.|..|..:..:  |...||.....|::
  Rat   190 AYLHPHPAPPHTPIIQIDQPEFDI---LLQQDQEQKVYAQILREYVTYLNRLGTLLGSNPQEAQQ 251

  Fly   252 TAKELIDFEVDLAQGLVDESEGLDVGELTQLLTVDEIQRRYSPTLD---IDRLLFVSMGERISDQ 313
            .|...|.|...|.|.|..:.:.....:|..::|:|.:| ..:|.:|   ..:.:|..|....|..
  Rat   252 HASWSIVFTSRLFQFLRPQQQQQAQDKLFHVVTIDALQ-EMAPAIDWLSCLQAIFTPMSLSPSQT 315

  Fly   314 IYEYNNRYQQNLVEVIKR---TPKRTVANYIFFRLI--------WEFVETPSDSPEKQMK----- 362
            :..::..|.:|:.::::.   .....:.:|:...|:        .:|.|...:..:|..|
  Rat   316 LQVHDLDYLRNMSQLVEEGLLNHSEIIQSYMILGLVDTLSPALATKFQEARRELTQKLRKLKERP 380

  Fly   363 ---------ACVDLTKKYFAKNLDNMFYRRYNNEKSSREIDNMWRQLKSTFNETLRSSPALNWIE 418
                     .||:.|..:|...|..:|...............::.::|......|:.   |:||.
  Rat   381 PLPAYPRWMKCVEQTGSFFEPTLAALFVHEAFGPSIRSAAMELFAEIKDAVIVRLKK---LSWIS 442

  Fly   419 RPTRNLAMAKLQAMTLEV-------------NNYADDNFTEEFAELNLQSDDYVENVRYTSLLGA 470
            ..||..|:.||..:.:|:             ..|:|......|    |||  ::..||  ||.|.
  Rat   443 EETRKEALNKLTQLQVEMGAPKRALKTEMAKQEYSDIQLGPSF----LQS--FLSCVR--SLQGR 499

  Fly   471 KQMREML-----HKPAK-PFEAGSQLSYTPANILIENTIKVPVALLQPFYIWSDVYPNAIMFGTL 529
            | :|..|     |:..| |:...:..| .|.::::     .|..||||.: :...||.|:.||.:
  Rat   500 K-VRSFLQPFPYHRWQKSPWSVSAYYS-VPDHVVV-----FPAGLLQPPF-FHPGYPRAVNFGAV 556

  Fly   530 ASLIGHELIHGFDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQYGRYVYDGI-QLKESTAQ 593
            .|::.|:|:|.|    .:|...|.... .|.::....|.   |...:|..:....: ....|...
  Rat   557 GSIMAHKLLHIF----FQFLLPGGCPA-CDTRALQEALL---CLEHRYAAFPLPSMSSFNGSHTL 613

  Fly   594 SENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWCNDAHPS 658
            .||.||.||:.:|:.||||    ::|...|     :.||||...:..||||.|:||..|.:.
  Rat   614 LENAADIGGVAIAFQAYRK----RITERTG-----ELTLPNQELSPYQLFFRSYAQVMCREL--- 666

  Fly   659 VKALQVSTDQHMPGRFRVIGSLSNFEEFSKEFNCPAGSAMNPSEKCILY 707
              ..|...|.|.|.|.||.|.|||..:|:|.|.||:||.:|||.:|.|:
  Rat   667 --ISQDPQDTHSPPRLRVHGPLSNSPDFAKHFLCPSGSLLNPSTRCKLW 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl21	NP_651646.2	PepO	57..707	CDD:226118	174/697 (25%)
		M13	63..704	CDD:189000	173/691 (25%)
Kel	NP_001178540.1	PepO	75..713	CDD:226118	174/697 (25%)
		M13	78..711	CDD:189000	173/692 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344528
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950