Protein Alignment Nepl21 and nep-24

DIOPT Version :9

• Sequence 1: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_503005.3
• Gene: nep-24 / 190993
• WormBaseID: WBGene00013786
• Length: 567
• Species: Caenorhabditis elegans
• Alignment Length: 581
• Identity: 120/581 - (20%)
• Similarity: 226/581 - (38%)
• Gaps: 132/581 - (22%)

  Fly    55 IESFMDQKADPCNDFYAFSCGNYKRINSALSMQVVTTGVFETLTKGLNRKILKMLNTPHDSHDTP 119
            :.::.|...|||::|:.|:||.        ..:..|..::...||.:|..:.:.|.....|....
 Worm    50 LHNYHDPSVDPCDNFHQFACGR--------EHEHETEDIYTKKTKTINNIMKRFLKKNETSRSKS 106

  Fly   120 EDIKVKHFYESCLQIKELNSTYSEKLKRL------IAEFGTMPLLEGSSWQEDDFDWLNTTARMA 178
            |: .::..|::|..: |.|||.|.. |.|      |...|..|::: ..|.|..||
 Worm   107 EN-AMRTLYKACKTL-EKNSTASRN-KALQDIFQDIQSIGAWPVVD-DKWDESKFD--------- 158

  Fly   179 YRYGITPIFGIEVNKDLASNTRNRIYLGQQDFPLEARSMYVDDATAVY--RQKYRNNIQRILQRY 241
                        :|..|.    |.:.||:::|.|...:.||:......  ...:|:|:.
 Worm   159 ------------LNDFLV----NLVRLGRKNFGLFQMARYVNVRNFAIGPEAAWRHNVD------ 201

  Fly   242 LG------VKMDLAKKTAKELIDFEVDLAQGLVDESEGLDVGELTQLLTVDEIQRR--YSPTLDI 298
            ||      :|.:..:...|:|:|   |||: .|:..:.|...:...:........|  :..:::.
 Worm   202 LGKTISEILKANSVQTNNKKLLD---DLAE-YVNLEKALSQHKFNTVQPGYIFSERSDFVSSVNF 262

  Fly   299 DRLLFVSMG---ERISDQIYEY------------NNRYQQNLVEVIKRTPKRTVANYIFFRLI-W 347
            .||:...|.   ..:..::|:.            ||    ||..:|:.|.||.:|||:.|:.| .
 Worm   263 SRLVLEMMSPDKRTLFPEVYQIMYLTNTSLFFGKNN----NLETIIRNTSKRALANYLIFKFIDT 323

  Fly   348 EFVETPSDSPEKQMKACVDLTKKYFAKNLDNMFYRRYNNEKSSREIDNMWRQLKSTFNETLRSSP 412
            ...:....||.   ..|......:..:.....|||.:.::::.::|..:   .::|..:.|:...
 Worm   324 SIADLTYGSPS---AFCEQKVINFLPRAALRAFYRNFISKENRKKITKL---TEATQVQLLKIIG 382

  Fly   413 ALNWIERPTRNLAMAKLQAMTLEVN--NYAD-----DNFTEEFAELNLQSDDYVENVRYTSLLGA 470
            |.:|:...::.:||.::.:|.:.:.  :|.|     |..   |..|||.|.|    ..||.:
 Worm   383 ATDWMSIKSKKIAMDRVSSMNMVIGYPDYFDPPGKLDGL---FEHLNLSSSD----TYYTVV--- 437

  Fly   471 KQMREMLHKPAKPFEAGSQLSYTP------------ANILIENTIKVPVALLQPFY---IWSDVY 520
            :::...:.:....:..| ::.|.|            ||   :|.:.:    ..||:   .:...:
 Worm   438 RKINRFMREQEMDYYTG-EVPYYPLFPGLMTNAMYNAN---DNNLMI----FAPFFDDPFFDSSF 494

  Fly   521 PNAIMFGTLASLIGHELIHGFDDSGRKFD-EKGNSKDWWDEKSSSNFLKRRDCFTKQYGRY 580
            |:.......::.:.||:.|.|  |....| ..|.::.|...|.:..:.||..|...||..|
 Worm   495 PDYANIAFTSNTLAHEMGHTF--SPHLMDIMTGTTEVWLTPKETEEYEKRVKCLEDQYTEY 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl21	NP_651646.2	PepO	57..707	CDD:226118	120/579 (21%)
		M13	63..704	CDD:189000	119/573 (21%)
nep-24	NP_503005.3	GluZincin	58..561	CDD:301352	119/573 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020