Protein Alignment Nepl21 and nep-2

DIOPT Version :9

• Sequence 1: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_494343.2
• Gene: nep-2 / 188090
• WormBaseID: WBGene00020230
• Length: 736
• Species: Caenorhabditis elegans
• Alignment Length: 706
• Identity: 198/706 - (28%)
• Similarity: 328/706 - (46%)
• Gaps: 84/706 - (11%)

  Fly    51 KTAE-IESFMDQKADPCNDFYAFSCGNYKRINSALSMQVVTTGVFETLTKGLNRKILKMLNTPHD 114
            |||. |.|.|:...|||:|||.|:||.:.: ...:.....:...||.|.:.|...:.::|    |
 Worm    60 KTASVILSSMNSSVDPCDDFYEFACGQWIK-GHPIPDDAPSVSNFENLGQDLEFALKELL----D 119

  Fly   115 SHDTPEDI------KVKHFYESCLQIKELNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDFDWLNT 173
            .:|.|.|.      |.|:||..||...|:...:......::..||..|.|......:...:.|
 Worm   120 ENDEPYDYETSAVGKAKYFYNLCLNESEILDNWRTTFDEVVKSFGGWPSLGHQMKPDASIEML-- 182

  Fly   174 TARMAYRYGITPIFGIEVNKDLASNTRNRIYLGQQDFPLEARSMYVDDATAVYRQKYRNNIQRIL 238
            .|.|..::....:|...|..|..::.|:.:.:.|....|.||..|| .|....|..|...|:.:|
 Worm   183 YADMVAKFKADSLFKATVQPDDKNSQRHVLLIDQPQLNLFARDFYV-AAENEERMAYLQLIRDVL 246

  Fly   239 QRYLGVKMDLAKKT--AKELIDFEVDLAQGLVDESEGLDVGELTQLLTVDEIQR---RYSPTLDI 298
               :.:..|..:.|  |||:||||..||...:.:....|:.||...:|:.|::|   .::..|..
 Worm   247 ---ILLDADRTRATLDAKEIIDFETALANITMADEHRHDIAELYTKITLGEMRRSLPHFNWPLFF 308

  Fly   299 DRL---LFVSMGERI----SDQIYEYNNRYQQNLVEVIKRTPKRTVANYI----FFR-------- 344
            :|:   |....|:||    :.::..|...:.:.|..:|.:...|.:.||:    ||:
 Worm   309 NRMFKDLHEKNGKRITFDDNTEVVVYGYEFLRRLDVLIPQYDNRLIVNYLEWCWFFKTMLRDLPD 373

  Fly   345 ----LIWEFVETPSDSPEKQMK--ACVDLTKKYFAKNLDNMFYRRYNNEKSSREIDNMWRQLKST 403
                .|::|.:|.:....::::  .||.............::.:.:.:.::.::::.|...:..:
 Worm   374 PFALTIFKFYKTLNIMNVQKVRWHGCVTRINSLMPMATSAIYVKNHFDHEAKQQVEEMISLIMES 438

  Fly   404 FNETLRSSPALNWIERPTRNLAMAKLQAMTLEVN--NYADD--NFTEEFAELNLQSDDYVENVRY 464
            |.:.|.|.   :|:.:.|:..|..|:..|..::.  :|.:|  ....|:....:....|.:
 Worm   439 FVDLLLSE---DWLTKETKQTAKQKVNEMKRKIGYPDYLNDPAAVNNEYKTFKVYPGHYYQ---- 496

  Fly   465 TSLLGAKQ-MREMLHKPAKPFE-----AGSQL---SYTPANILIENTIKVPVALLQPFYIWSDVY 520
            |.....:| .|::|.:..:..:     ||:.|   .|:|..    |.|..|..:|||.: :|..:
 Worm   497 TKFSFYEQYQRDVLERITEAVDRERWVAGAALVNAFYSPNT----NEIIFPAGILQPVF-YSKDF 556

  Fly   521 PNAIMFGTLASLIGHELIHGFDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQYGRYVYDGI 585
            |:::.||.:..:||||:.|||||.||.:|..||.:.|||..:.|.|..:..|..|||..||.|.|
 Worm   557 PSSMNFGGIGVVIGHEITHGFDDRGRLYDNLGNIRQWWDNATISKFEHKAQCIEKQYSSYVLDQI 621

  Fly   586 --QLKESTAQSENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISFA 648
              |:...:.:.||||||||::.||.||:| ||.:.:.|        ..||.:..|..||||:::|
 Worm   622 NMQINGKSTKGENIADNGGLKQAYRAYKK-YEKRHSRP--------PRLPGVNLTHDQLFFLNYA 677

  Fly   649 QSWCNDAHPSVKALQVSTDQHMPGRFRVIGSLSNFEEFSKEFNCPAGSAMNPSEKC 704
            |.||...:......::.|.:|.||..||.|.|||..:|:|.:||..||.|||.|||
 Worm   678 QIWCGTMNDKEAIRKLRTSEHSPGPIRVKGPLSNSYDFAKAYNCEPGSQMNPREKC 733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl21	NP_651646.2	PepO	57..707	CDD:226118	194/699 (28%)
		M13	63..704	CDD:189000	190/691 (27%)
nep-2	NP_494343.2	PepO	61..736	CDD:226118	197/705 (28%)
		M13	73..734	CDD:189000	192/693 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020