Protein Alignment Nepl21 and nep-3

DIOPT Version :9

• Sequence 1: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: NP_494679.2
• Gene: nep-3 / 173730
• WormBaseID: WBGene00016778
• Length: 634
• Species: Caenorhabditis elegans
• Alignment Length: 704
• Identity: 155/704 - (22%)
• Similarity: 270/704 - (38%)
• Gaps: 169/704 - (24%)

  Fly    40 TPYMKELLRQAKTAEIESFMDQKADPCNDFYAFSCGNYKRIN------SALSMQVVTTGVFETLT 98
            ||....|:.|     :.:|.|...|||.:||..:||.|...|      :|...|:|
 Worm    64 TPECITLVHQ-----LLNFQDPSVDPCENFYQAACGKYNEHNVIDGSRTAQKQQIV--------- 114

  Fly    99 KGLNRKILKMLNTPHDSHDTPEDIKVKHFYESCLQIKEL----NSTYSEKLKRLIAEFGTMPLLE 159
                :::::.....:.|..:..:..:|..||.|.:.|.:    |....:::...|.:.|:.|:|:
 Worm   115 ----KRLIRDFLHKNQSSTSKSENSMKLLYEKCKEAKTIKVLGNQNLLQEIFMNIQKIGSWPVLD 175

  Fly   160 GSSWQEDDFDWLNTTARMAYRYGIT--PIFGIEVNKDLASNTRNRIYLGQQDFPLEARSMYVDDA 222
             .:|....|: ||.......|.|::  ..|.|.::.|.....:     ..::||.
 Worm   176 -ENWDGKKFN-LNEMLLSLIRLGVSNFGFFEIIISSDAFVEIK-----PARNFPT---------- 223

  Fly   223 TAVYRQKYRNNIQRILQRYLGVKMDLAKKTAKELIDFEVDLAQGLVDESEGLDVGELTQLLTVDE 287
                    |.|:..|:.:                    |.|..|
 Worm   224 --------RENLSDIISK--------------------VFLGNG--------------------- 239

  Fly   288 IQRRYSPTLDIDRLLFVSMGERISDQIYEYNN--RYQQNLVEVIKRTPKRTVANYIFFRLIWEFV 350
                :.|.:           ..|.:.:.||.|  |..::|..:|:.||.|::.||:.|..:...:
 Worm   240 ----FQPNI-----------TAIENDLREYENLQRELKSLERLIQTTPNRSLVNYLIFNYLKSVM 289

  Fly   351 ETPSDSPEKQMKACVDLTKKYFAKNLDNMFYRRYNNEKSSREIDNMWRQLKSTFNETLRSSPALN 415
            ......||:|   |..:...:..:....:|.:.:.::::.:.:..|...:|..|.:.::.|   .
 Worm   290 LEYKRLPEEQ---CEGVVIDFLPRASTRVFVQNFLDKENRKYVAGMIEDVKMGFIDMIQES---T 348

  Fly   416 WIERPTRNLAMAKLQAMTLEVNNYAD-----DNFTEEFAELNL-QSDDYVENVRYTSLLGAKQMR 474
            |:...::.:|:.|::.:...: .|.|     ......|.:||: |:|.|...||.......:|..
 Worm   349 WLNEESKKVAVQKVKNIKSMI-GYPDFFEPPGTLDRSFKDLNIEQTDSYHTIVRKIQKFTNEQCM 412

  Fly   475 EMLHKPAKPFEAGSQLSYTP------ANILIENT----IKVPVALLQPFYIWSDVYPNAIMFGTL 529
            |.:         .|::...|      ||...:||    |..|| |..|  |:...:|..:....:
 Worm   413 EFV---------ASEIPLDPRQPILHANAFYQNTNFLAILAPV-LDDP--IFDTTFPRYVNLAVI 465

  Fly   530 ASLIGHELIHGFDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQYGRYVYD----GIQLKES 590
            .:::.||:.|.||.:|..:|:.|..:.|...:.|..:.||..|..:|:..  ||    |..|..|
 Worm   466 GNVLAHEIGHAFDHTGINYDDAGQQRIWLTPEDSEEYGKRLRCLLRQHDE--YDDPDFGRNLNGS 528

  Fly   591 TAQSENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISFAQSWC--N 653
            ....|..||..|:..|:..::|     |.|.|     ..|.:....:...||:|.:.|..||  .
 Worm   529 KTLHEISADRFGVEAAWRTFKK-----LDLSN-----ESEIVGFQNFNIDQLYFRTAALIWCRQR 583

  Fly   654 DAHPSVKALQVSTDQHMPGRFRVIGSLSNFEEFSKEFNCPAGSAMNPSEKCILY 707
            |......|||   .:|....|||.|..:|..:|::.||||.||.|||.:||.|:
 Worm   584 DTTDLQYALQ---REHPTNNFRVNGIYANMPQFAETFNCPLGSPMNPKKKCDLF 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl21	NP_651646.2	PepO	57..707	CDD:226118	150/685 (22%)
		M13	63..704	CDD:189000	146/676 (22%)
nep-3	NP_494679.2	M13	82..631	CDD:189000	146/676 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020