Protein Alignment Nepl21 and mme

DIOPT Version :10

• Sequence 1: NP_651646.2
• Gene: Nepl21 / 43413
• FlyBaseID: FBgn0027578
• Length: 707
• Species: Drosophila melanogaster
• Sequence 2: XP_031758820.1
• Gene: mme / 101734885
• XenbaseID: XB-GENE-1011098
• Length: 746
• Species: Xenopus tropicalis
• Alignment Length: 775
• Identity: 202/775 - (26%)
• Similarity: 337/775 - (43%)
• Gaps: 127/775 - (16%)

  Fly    10 KQLLCICI-AGHVLSAMVAAAPTSEEDLKQDTPYMKELLRQAKTAEIESFMDQKADPCNDFYAFS 73
            |.|:.:|| .|.:..||:.|..||.:.:......:      :..|.|.:.||...|||||||.::
 Frog    22 KGLIILCIFLGIISIAMILAYATSNDGICTSQACI------STAARIIANMDAATDPCNDFYQYA 80

  Fly    74 CGNYKRINSALSMQVVTTGVFETLTKGLNRKILKMLNTPHDSHDTPEDIKVKHFYESCLQ--IKE 136
            ||.:.:.|......:| :..|:.|...: ..:||.......:.|.|...|||.||:||:.  ||.
 Frog    81 CGGWLKKNRIPDNNIV-SNTFDILRTDI-EVVLKDALEKESADDIPAIKKVKTFYKSCIDETIKN 143

  Fly   137 LNSTYSEKLKRLIAEFGTMPLLEGSSWQEDDFDW-----------------LNTTARMAYRYGIT 184
            |     .|...||.   |:|.|         :||                 ..:.|....:||.:
 Frog   144 L-----RKGGPLIK---TLPAL---------YDWPIAVDNWETRYGLVWSAQESIAGFITKYGQS 191

  Fly   185 PIFGIEVNKDLASNTRNRIYLGQQDFPLEARSMY-----VDDATAVYRQKYRNNIQRI-LQRYLG 243
            .:..:.|::||.:::...:::.|....|.::..|     .:.|...|.::..:....| .:|.|.
 Frog   192 GLINVYVSEDLTNSSTYILHIDQPGLGLPSKDYYDCKGTSEIACLAYMEQMVSVAMLIRKERNLT 256

  Fly   244 VKMDLAKKTAKELIDFEVDLAQGLVDESEGLDVGELTQLLTVDEIQRRYSPTLDIDRLLFVSMGE 308
            :..|......:::...|.::|:....|....::.::.:.:|:..|.:.|...::...:.::.:..
 Frog   257 INEDKILSEMEKVFKLEREIAKAEASEEIRENLNDIYKKMTLSGIAKTYPLKMNDQNINWLKLIN 321

  Fly   309 RI----------SDQIYEYNNRYQQNLVEVIKRTPKRTVANYIFFRLIWEFVETPS--------- 354
            .|          ::|:....:.|.:.| ..:.:...|.:.||:.:|.|...:...|
 Frog   322 AIISPGGVSIEENEQVALICSDYLKKL-RFLNKYKARELQNYLGWRYILSAINDLSLEYKNTGIH 385

  Fly   355 -------DSPE-KQMKACVDLTKKYFAKNLDNMFYRRYNNEKSSREIDN---------MWRQLKS 402
                   ::.| ...:.||    .|...|:::...|.|..|..|.:|::         :..:::.
 Frog   386 LKKALYGNAAEGSDWQTCV----TYLNDNMEDAIGRLYLKETLSADIEHVKVKDKVKEIIAEIRR 446

  Fly   403 TFNETLRSSPALNWIERPTRNLAMAKLQAMTLEV---NNYADD-NFTEEFAELNLQSDDYVENVR 463
            .|.|.|..   ::|::..|:..|..|:.::...:   .:..|| ...|.::||..:.|:..||.:
 Frog   447 AFLEMLEE---MDWMDEDTKKRAARKVASINERIAFSEDIMDDFKLNEGYSELEFRVDELFENKQ 508

  Fly   464 YTSLLGAKQMREMLHKPAKPFE--AGSQLSYTPANI-----LIENTIKVPVALLQ-PFYIWSDVY 520
            .......|:|...|.|.....|  .|      ||::     |..|.|..|..:|| ||:  |...
 Frog   509 KYIEFVQKKMTSRLRKQVNKNEWVPG------PAHVNAFYSLTYNEIVFPAGILQTPFF--SSSQ 565

  Fly   521 PNAIMFGTLASLIGHELIHGFDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQYGRYVYD-- 583
            |:|:.:|.:..:||||:.||||:.|..|||.||..:||...|..||.....||..|||.|.:|
 Frog   566 PSALNYGGIGMIIGHEITHGFDNRGCNFDEHGNLVNWWTNASMMNFSNLSQCFVNQYGNYSWDEA 630

  Fly   584 -GIQLKESTAQSENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQLFFISF 647
             |..|...:...|||:||||:|.||.|::.:.::.      .:|   :.||.:...:.|||||||
 Frog   631 GGQYLNGISTLGENISDNGGIRGAYRAFKNYVKSH------KED---DLLPGIDLDSDQLFFISF 686

  Fly   648 AQSWCNDAHPSVKALQVSTDQHMPGRFRVIGSLSNFEEFSKEFNCPAGSAMNPSEKCILY 707
            .|.||....|...|..:.|..|.||.|||||:|.|..||||.|:|...:.|||:.||.|:
 Frog   687 GQIWCGMHRPEYAATLIKTGSHTPGIFRVIGTLQNSPEFSKAFSCCNNAYMNPAVKCKLW 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl21	NP_651646.2	M13	63..704	CDD:341056	185/716 (26%)
mme	XP_031758820.1	M13	71..744	CDD:341056	186/716 (26%)