Protein Alignment Nepl20 and Ece1

DIOPT Version :9

• Sequence 1: NP_651645.1
• Gene: Nepl20 / 43412
• FlyBaseID: FBgn0039613
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_006239337.1
• Gene: Ece1 / 94204
• RGDID: 620293
• Length: 769
• Species: Rattus norvegicus
• Alignment Length: 713
• Identity: 201/713 - (28%)
• Similarity: 316/713 - (44%)
• Gaps: 115/713 - (16%)

  Fly    46 AEIESFMNQKVDPCKDFYAFSCGNYKRINSALNMRVLTTGVFETLTKGLNRKILKML--NTPHDS 108
            :.|.:.|:..||||:||::::||.:.:.|...:.. ...|.|..|.:. |:.|:|.|  |:...:
  Rat   108 SSILNSMDPTVDPCQDFFSYACGGWIKANPVPDGH-SRWGTFSNLWEH-NQAIIKHLLENSTASA 170

  Fly   109 HDTPEDIQVKHFYESCLQIKELNSTYSEKLKRLIAEFG----TMPLLEGSSWQEDDFDWLNTTAR 169
            .:..:..||  :|.:|:....:....::.|..||.:.|    |.|      |.:|:|.  :|...
  Rat   171 SEAEKKAQV--YYRACMNETRIEELRAKPLMELIEKLGGWNITGP------WAKDNFQ--DTLQV 225

  Fly   170 MAHRYGIMSIIGVGVATDFANNQKNIIYINQQEFPLKTRSMYM---DNETAIYRQNYQNNIQLIL 231
            :...|.......|.|:.|..|:..|:|.::|....|.:|..|:   :||..:  ..|. |..:.|
  Rat   226 VTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEKVL--TGYL-NYMVQL 287

  Fly   232 EKYLGVKDE-LARKAAKEMFEFEVDLAHGLVDNNKHLNLRDLIELLTVAELRE-----RYAPTLD 290
            .|.||..|| ..|...:::.:||..||:..:...|..:...:...:|.|||:.     .:.|.|:
  Rat   288 GKLLGGGDEDSIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLN 352

  Fly   291 TDQLIFVSMGEKISDKVYEYNRRYQQNLVEVIERTPKSTVANYLFLRLIWEFIQKPSGVAE---- 351
            .   ||..:....|:.:..|::.|.:.:..:|..|.|..:.||    ::|..::|.|...:
  Rat   353 A---IFYPVEINESEPIVVYDKEYLRQVSTLINSTDKCLLNNY----MMWNLVRKTSSFLDQRFQ 410

  Fly   352 -------------KPT-----EACVDFTKTYFAKNLDNMIYRRYKNEKSSREIDSMWHQLKSTFK 398
                         |.|     :.||..|:......|..|..:....|.|......:..::|..|:
  Rat   411 DADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNIASEIILEIKKAFE 475

  Fly   399 ETLLSSPALDWIEPSTRSLAIAKLEAM--TLEVNNYVKE--------NFTEEFADLNLQNT---- 449
            |:|   ..|.|::..||..|..|.:|:  .:...|::.:        |......||..:|.
  Rat   476 ESL---STLKWMDEDTRRSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFF 537

  Fly   450 -----DCVENLRQV----QMLQAKQMRQLYHQPAKPLEAGELLSYTPSNILLENSIKVPVALLQ- 504
                 ...:.||:.    |......|...|:.|.|                  |.|..|..:||
  Rat   538 NFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTK------------------NEIVFPAGILQA 584

  Fly   505 PFYIWSDVYPNAVMFGTLAYLIGHELIHGFDDSGRKFDEKGNSKDWWDEKSSSNFLKRRDCFTKQ 569
            |||..|.  |||:.||.:..::||||.|.|||.||::|:.||.:.||...|...|.::.:|..:|
  Rat   585 PFYTRSS--PNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTECMVQQ 647

  Fly   570 YGRYVYDGIQLKESTAQSENIADNGGMRLAYTAYRKWYENQLTLPNGAQDMTKETLPNLRYTAKQ 634
            |..|..:|..:.......||||||||::.||.||:.|.:.     |||:    :.||.|..|:.|
  Rat   648 YNNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKK-----NGAE----QILPTLGLTSNQ 703

  Fly   635 LFFISFAQSWCNDVHPKVKALQVSTDDHMPGKFRVIGTLSNFEEFSKEFNCHAGSAMNPIEKC 697
            |||:.|||.||:...|:.....:.||.|.|.:|||||:|||.:|||:.|.|..||.|||..||
  Rat   704 LFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPLGSPMNPRHKC 766

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nepl20	NP_651645.1	PepO	50..691	CDD:226118	195/701 (28%)
		M13	56..697	CDD:189000	197/701 (28%)
Ece1	XP_006239337.1	PepO	105..769	CDD:226118	201/713 (28%)
		M13	118..767	CDD:189000	199/703 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344489
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282463at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11733
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.850